Skip to main content
Log in

Left main coronary thrombosis with essential thrombocythemia

  • Published:
Journal of Thrombosis and Thrombolysis Aims and scope Submit manuscript

Abstract

Essential thrombocythemia is a disorder that causes persistent increase in the platelet count. The disease is associated with an elevated risk of thrombosis. A 71-year-old woman was diagnosed with left main coronary thrombosis after an angiogram due to stable angina. One week before the angiogram was taken the patient had also been diagnosed with essential thrombocythemia. After appropriate medical treatment for 5 days the patient underwent an excimer laser treatment, which failed in dissolving the thrombus. Before the patient underwent coronary surgery, thrombopheresis was performed in order to reduce the platelet count. After a successful coronary operation the patient improved completely.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Passamonti F, Rumi E, Pungolino E, Malabarba L, Bertazzoni P, Valentini M, et al (2004) Life expectancy and prognostic factors for survival in patients with polycythemia vera and essential thrombocythemia. Am J Med 117:755–761

    Article  PubMed  Google Scholar 

  2. Cortelazzo S, Viero P, Finazzi G, D’Emilio A, Rodeghiero F, Barbui T (1990) Incidence and risk factors for thrombotic complications in a historical cohort of 100 patients with essential thrombocythemia. J Clin Oncol 8:556–562

    CAS  PubMed  Google Scholar 

  3. Harrison CN, Gale RE, Machin SJ, Linch DC (1999) A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications. Blood 93:417–424

    CAS  PubMed  Google Scholar 

  4. van Genderen PJ, Lucas IS, van Strik R, Vuzevski VD, Prins FJ, van Vliet HH, et al (1996) Erythromelalgia in essential thrombocythemia is characterized by platelet activation and endothelial cell damage but not by thrombin generation. Thromb Haemost 76:333–338

    PubMed  Google Scholar 

  5. Michaels AD, Whisenant B, MacGregor JS (1998) Multivessel coronary thrombosis treated with abciximab (ReoPro) in a patient with essential thrombocythemia. Clin Cardiol 21:134–138

    Article  CAS  PubMed  Google Scholar 

  6. Rocca B, Ciabattoni G, Tartaglione R, Cortelazzo S, Barbui T, Patrono C, et al (1995) Increased thromboxane biosynthesis in essential thrombocythemia. Thromb Haemost 74:1225–1230

    CAS  PubMed  Google Scholar 

  7. Harrison CN, Donohoe S, Carr P, Dave M, Mackie I, Machin SJ (2002) Patients with essential thrombocythaemia have an increased prevalence of antiphospholipid antibodies which may be associated with thrombosis. Thromb Haemost 87:802–807

    CAS  PubMed  Google Scholar 

  8. Daya SK, Gowda RM, Landis WA, Khan IA (2004) Essential thrombocythemia-related acute ST-segment elevation myocardial infarction. A case report and literature review. Angiology 55:319–323

    Article  PubMed  Google Scholar 

  9. Topaz O, Ebersole D, Das T, Alderman EL, Madyoon H, Vora K, et al (2004) (the CARMEL multicenter trial). Excimer laser angioplasty in acute myocardial infarction. Am J Cardiol 93:694–701

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zekeriya Nurkalem.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nurkalem, Z., Uslu, N., Gorgulu, S. et al. Left main coronary thrombosis with essential thrombocythemia. J Thromb Thrombolysis 22, 165–167 (2006). https://doi.org/10.1007/s11239-006-9016-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11239-006-9016-5

Keywords

Navigation