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Laccase from prokaryotes: a new source for an old enzyme

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Abstract

Laccases (benzenediol: oxygen oxidoreductase, EC 1.10.3.2) are multi-copper-containing enzymes capable of catalyzing the oxidation of a wide range of phenolic and non phenolic aromatic compounds. The available data indicates that laccases from prokaryotes are promising biological tools for green chemistry based applications, especially in decolorization of industrial textile dye effluents which constitute a major threat to soil and ground water reservoirs worldwide. Another appropriate application of prokaryotic laccases is bio-bleaching of different kind of pulps where there is indiscriminate use of hazardous chlorine based chemicals for brightness of the paper. In recent years, researchers have shown interest in the identification and characterization of laccases from prokaryotic sources. This catalyst is not commonly reported from this kingdom, although prokaryotes have immense environmental adaptability and biochemical versatility. Moreover, true laccases or laccase-like enzymes exist in many gram-negative, gram-positive bacteria and actinomycetes. Corresponding genes have been identified and functionally expressed in genetically developed hosts. This review summarizes the research efforts to characterize laccases and their properties from different prokaryotic sources, including bacteria and actinomycetes.

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  1. Gursharan Singh

    Present address: Dairy and Swine Research and Development Center, Agriculture and Agri-Food Canada, 2000, College Street, Sherbrooke, QC, J1M 0C8, Canada

Authors and Affiliations

  1. Department of Microbiology, Panjab University, Chandigarh, 160014, India

    Gursharan Singh & Prince Sharma

  2. Department of Chemical and Biological Engineering, South Dakota School of Mines and Technology, Rapid City, SD, USA

    Aditya Bhalla

  3. Department of Veterinary Parasitology, College of Veterinary Science (GADVASU), Ludhiana, India

    Paramjit Kaur

  4. Department of Biotechnology, Panjab University, Chandigarh, 160014, India

    Neena Capalash

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Singh, G., Bhalla, A., Kaur, P. et al. Laccase from prokaryotes: a new source for an old enzyme. Rev Environ Sci Biotechnol 10, 309–326 (2011). https://doi.org/10.1007/s11157-011-9257-4

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