Abstract
Production of radioactive scandium by irradiating natural titanium metal in Pakistan Research Reactor-1 was evaluated. The production rate of 47Sc and other radioactive scandium was estimated. High specific activity 47Sc can be produced by irradiating enriched 47Ti in sufficient quantities needed for therapeutic applications. A new separation technique based on column chromatography was developed. Neutron irradiated titanium was dissolved in hydrofluoric acid, which was evaporated and taken in distilled water. The resulting solution was loaded on silica gel column. The radioactive scandium comes out first and the inactive titanium is removed with 2 M HCl. More than 95% radioactive scandium was recovered, while chemical impurity of titanium determined by optical emission spectroscopy was less than 0.01 μg/mL in final product.
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Rosoff B, Spenser H, Cohn SH, Gusmano EA (1965) Int J Appl Radiat Isot 16:479
Khandaker MU, Kim K, Lee MW, Kim KS, Kim GN, Cho YS, Lee YO (2009) Appl Radiat Isot 67:1348
Greene MW (1967) Int J Appl Radiat Isot 18:540
Grignon C, Barbet J, Bardie’s M, Carlier T, Chatal JF, Couturier O, Cussonneau JP, Faivre A, Ferrer L, Girault S, Haruyama T, LeRay P, Luquin L, Lupone S, Metivier V, Morteau E, Servagent N, Thers D (2007) Nucl Instrum Methods Phys Res A 571:142
Erdtmann G (1976) Neutron activation tables. Verlag Chemie, Weinheim, New York
Baer RW, Payne BD, Verrier ED, Vlahakes GJ, Molodowitch D, Uhlig PN, Hoffman JI (1984) Am J Physiol Heart Circ Physiol 246(3):H418
Wehner AP, Wilerson CL, Stevens DL (1984) Environ Res 35(1):211
Yagi M, Kondo K (1977) Int JAppl Radiat Isot 28:463
Kolsky KL, Joshi V, Mausner LF, Srivastava SC (1998) Appl Radiat Isot 49:1541
Petrelli L, Mausner LF, Kolsky KL (1992) J Radioanal Nucl Chem 157:335
Alimarin IP, Ivanov NA, Gibalo IM (1969) Zh Anal Khim 24:1521
Das NR, Banergee S, Lahiri S (1995) Radiochim Acta 69:61
Lahiri S, Banerjee S, Das NR (1996) Appl Radiat Isot 47:1
Aly HF, El-Haggan MA (1971) Microchim Acta 59:4
Das MK, Sarkar BR, Ramamoorthy N (1990) Radiochim Acta 50:135
Abdel-Rassoul AA, Mohammed S (1964) Z Anorg Chem 330:96
Walter RI (1958) J Inorg Nucl Chem 6:63
Gile JD, Garrison WM, Hamilton JG (1950) J Chem Phys 18:1685
Calamand A (1973) Cross sections for fission neutron induced reactions INDC (NDS)-55/L, IAEA, Vienna, September 1973
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Bokhari, T.H., Mushtaq, A. & Khan, I.U. Separation of no-carrier-added radioactive scandium from neutron irradiated titanium. J Radioanal Nucl Chem 283, 389–393 (2010). https://doi.org/10.1007/s10967-009-0370-6
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DOI: https://doi.org/10.1007/s10967-009-0370-6