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Two New Furo[3,2-c]Quinolines from the Stems of Nicotiana tabacum and Their Anti-Tobacco Mosaic Virus Activity

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Chemistry of Natural Compounds Aims and scope

Two new (1 and 2), together with two known (3 and 4), quinoline alkaloids were isolated from the stems of Nicotiana tabacum. Their structures were elucidated using spectroscopic methods, including extensive 1H, 13C, and 2D NMR techniques. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 exhibited potential anti-TMV activity with inhibition rates of 28.2 and 25.8% respectively.

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Acknowledgment

This work was supported financially by the Foundation of Yunnan basic research program (2019FD086), the National Natural Science Foundation of China (No. 21967021).

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Authors and Affiliations

  1. School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, 650500, Kunming, P. R. China

    Hua-Yin Liu, Meng-Jie Liang, Ya-Dong Guo & Liang Deng

  2. Key Laboratory of Tobacco Chemistry of Yunnan Province, China Tobacco Yunnan Industrial Co., Ltd., 650231, Kunming, P. R. China

    Hua-Yin Liu, Feng-Xian Yang, Hai-Tao Huang, Xin Liu, Xue-Mei Li, Wei-Song Kong, Qi-Li Mi, Guang-Yu Yang & Jian-Duo Zhang

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  1. Hua-Yin Liu
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  5. Xin Liu
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Correspondence to Liang Deng or Jian-Duo Zhang.

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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2022, pp. 600–602.

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Liu, HY., Yang, FX., Liang, MJ. et al. Two New Furo[3,2-c]Quinolines from the Stems of Nicotiana tabacum and Their Anti-Tobacco Mosaic Virus Activity. Chem Nat Compd 58, 708–711 (2022). https://doi.org/10.1007/s10600-022-03773-z

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  • DOI: https://doi.org/10.1007/s10600-022-03773-z

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