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Steroids from an Endophytic Eurotium rubrum Strain

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Chemistry of Natural Compounds Aims and scope

A new steroid, 3β,5α-dihydroxy-10α-methyl-6β-acetoxy-ergosta-7,22-diene (1), and ten known steroids (2–11), were isolated from the cultures of Eurotium rubrum, an endophytic fungus isolated from the marine green alga Codium fragile. Structures of these compounds were unambiguously established by spectroscopic techniques and by comparison with literature values. These steroids exhibited low activity to inhibit acetylcholinesterase and no activity against plant pathogenic fungi Colletotrichum lagenarium and Fusarium oxysporium.

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References

  1. T. S. Bugni and C. M. Ireland, Nat. Prod. Rep., 21, 143 (2004).

    Article  CAS  PubMed  Google Scholar 

  2. H. Lu, W. X. Zou, J. C. Meng, J. Hu, and R. X. Tan, Plant Sci., 151, 67 (2000).

    Article  CAS  Google Scholar 

  3. H. Kawagishi, R. Katsumi, T. Sazawa, T. Mizuno, T. Hagiwara, and T. Nakamura, Phytochemistry, 27, 2777 (1988).

    Article  CAS  Google Scholar 

  4. V. Piccialli and D. Sica, J. Nat. Prod., 50, 915 (1987).

    Article  CAS  Google Scholar 

  5. R. Y. Chen, Y. W. Wang, and D. Q. Yu, Acta Bot. Sin., 33, 65 (1991).

    CAS  Google Scholar 

  6. Y. Takaishi, M. Uda, T. Ohashi, K. Nakano, K. Murakami, and T. Tomimatsu, Phytochemistry, 30, 4117 (1991).

    Article  CAS  Google Scholar 

  7. T. Ishizuka, Y. Yaoita, and M. Kikuchi, Chem. Pharm. Bull., 45, 1756 (1997).

    Article  CAS  Google Scholar 

  8. J. M. Yue, S. N. Chen, Z. W. Lin, and H. D. Sun, Phytochemistry, 56, 801 (2001).

    Article  CAS  PubMed  Google Scholar 

  9. A. Smania, E. F. A. Smania, F. D. Monache, M. G. Pizzolatti, and G. D. Monache, Z. Naturforsch., 61C, 31 (2006).

    Google Scholar 

  10. A. C. Keller, M. P. Maillard, and K. Hostettmann, Phytochemistry, 41, 1041 (1996).

    Article  CAS  PubMed  Google Scholar 

  11. K. E. Schulte, G. Rucker, and H. Fachmann, Tetrahedron Lett., 9, 4763 (1968).

    Article  Google Scholar 

  12. S. Lopez, J. Bastida, F. Viladomat, and C. Codina, Life Sci., 71, 2521 (2002).

    Article  CAS  PubMed  Google Scholar 

  13. B. Schulz, J. Sucker, H. J. Aust, K. Krohn, K. Ludewig, P. G. Jones, and D. Doring, Mycol. Res., 99, 1007 (1995).

    Article  CAS  Google Scholar 

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Acknowledgment

This work was financially supported by the Chinese Academy of Sciences for Key Topics in Innovation Engineering (KZCX2-YW-QN209, KSCX2-YW-G-073).

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Correspondence to Ming-Feng Qiao.

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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2017, pp. 578–580.

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Qiao, MF., Yi, YW. & Deng, J. Steroids from an Endophytic Eurotium rubrum Strain. Chem Nat Compd 53, 678–681 (2017). https://doi.org/10.1007/s10600-017-2089-x

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  • DOI: https://doi.org/10.1007/s10600-017-2089-x

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