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The Synthesis and Cytotoxic Properties of Selenopheno[3,2-c]- and Selenopheno-[2,3-c]quinolones*

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Chemistry of Heterocyclic Compounds Aims and scope

We have developed a method for the synthesis of novel selenophene-containing polycyclic heterocycles, derivatives of selenopheno[3,2-c]- and selenopheno[2,3-c]quinolones. The cytotoxic activity of these compounds was studied in vitro. The molecular structure of 3-bromo-5-methyl-2-(piperidin-2-ylmethyl)selenopheno[3,2-c]quinolin-4(5H)-one was confirmed by X-ray analysis.

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Authors and Affiliations

  1. Latvian Institute of Organic Synthesis, 21 Aizkraukles St., Riga, LV-1006, Latvia

    P. Arsenyan, J. Vasiljeva, I. Shestakova, I. Domracheva & S. Belyakov

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  1. P. Arsenyan
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  2. J. Vasiljeva
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  3. I. Shestakova
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  4. I. Domracheva
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  5. S. Belyakov
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Correspondence to P. Arsenyan.

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*Dedicated to Academician J. Stradiņš on the occasion of his 80th birthday.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1804-1811, November, 2013.

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Arsenyan, P., Vasiljeva, J., Shestakova, I. et al. The Synthesis and Cytotoxic Properties of Selenopheno[3,2-c]- and Selenopheno-[2,3-c]quinolones*. Chem Heterocycl Comp 49, 1674–1680 (2014). https://doi.org/10.1007/s10593-014-1419-1

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  • DOI: https://doi.org/10.1007/s10593-014-1419-1

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