Abstract
In recent years, nanofibrous mats derived from biopolymers have attracted more interest and attention for biomedical applications, such as wound dressing, tissue engineering, and drug delivery. In this study, carboxymethyl cellulose/Ag nanoparticles (CMC/Ag NPs) nanofibrous membranes were prepared via a simple and green method in which electrospun CMC/poly(ethylene oxide) membranes were immersed in AgNO3 solution, followed by reduction of Ag+–Ag NPs upon ultraviolet (UV) irradiation. Notably, as evidenced by Fourier-transform infrared (FTIR), X-ray diffraction (XRD), and thermogravimetric (TG) analyses, poly(ethylene oxide) was eliminated during the immersion process and CMC nanofibrous mats containing Ag NPs were obtained. The effects of UV wavelength, AgNO3 solution concentration, and irradiation time on the morphology of the CMC/Ag NPs membranes were investigated, revealing optimal parameters (254 nm wavelength, 0.1 mol/L AgNO3 solution, and 10 min irradiation time) under which Ag NPs with average diameter of 20 nm were uniformly distributed on the surface of fibers. Antibacterial tests indicated that the antibacterial efficiency against Escherichia coli and Staphylococcus aureus of the obtained CMC/Ag NPs membranes reached up to 100 %, suggesting great potential for use as antimicrobial dressings.
Similar content being viewed by others
References
Abdel-Halim ES, Al-Deyab SS (2011) Utilization of hydroxypropyl cellulose for green and efficient synthesis of silver nanoparticles. Carbohydr Polym 86:1615–1622
Abdelrahman AM, Hudson SM, Rojas OJ (2014) Antimicrobial wound dressing nanofiber mats from multicomponent (chitosan/silver-NPs/polyvinyl alcohol) systems. Carbohydr Polym 100:166–178
Akbarian M, Olya ME, Ataeefard M, Mahdavian M (2012) The influence of nanosilver on thermal and antibacterial properties of a 2 K waterborne polyurethane coating. Prog Org Coat 75:344–348
Arvand M, Mirzaei E, Derakhshan MA, Kharrazi S, Sadroddiny E, Babapour M, Mahidi RF (2015) Fabrication of antibacterial silver nanoparticle-modified chitosan fibers using Eucalyptus extract as a reducing agent. J Appl Polym Sci. doi:10.1002/app.42133
Beele H, Meuleneire F, Nahuys M, Percival SL (2010) A prospective randomised open label study to evaluate the potential of a new silver alginate/carboxymethylcellulose antimicrobial wound dressing to promote wound healing. Int Wound J 7:262–270
Bizarria MTM, Avila MAD, Mei LHI (2014) Non-woven nanofiber chitosan/PEO membrane obtained by electrispinning. Braz J Chem Eng 31:57–68
Bogle KA, Dhole SD, Bhoraskar VN (2006) Silver nanoparticles: synthesis and size control by electron irradiation. Nanotechnology 17:3204–3208
Chen J, Wang J, Zhang X, Jin YL (2008) Microwave-assisted green synthesis of silver nanoparticles by carboxymethyl cellulose sodium and silver nitrate. Mater Chem Phys 108:421–424
Chen M, Wang LY, Han JT, Zhang JY, Li ZY, Qian DJ (2006) Preparation and study of polyacrylamide-stabilized silver nanoparticles through a one-pot process. J Phys Chem B 110:11224–11231
Demirsoy N, Ucar N, Onen A, Karacan I, Eren O, Borazan I (2015) The effect of dispersion technique, silver particle loading, and reduction method on the properties of polyacrylonitrile-silver composite nanofiber. J Ind Text doi:10.1177/1528083714553690
El-Sheikh MA, El-Rafie SM, Abdel-Halim ES, El-Rafie MH (2013) Green synthesis of hydroxyethyl cellulose-stabilized silver nanoparticles. J Polym. doi:10.1155/2013/650837
Frenot A, Henriksson MW, Walkenstrom P (2007) Electrospinning of cellulose-based nanofibers. J Appl Polym Sci 103:1473–1482
Frey MW (2008) Electrospinning cellulose and cellulose derivatives. Polym Rev 48:378–391
Fukami J, Yonemochi E, Yoshihashi Y, Terada K (2006) Evaluation of rapidly disintegrating tablets containing glycine and carboxymethylcellulose. Int J Pharm 9:101–109
Gaddy GA, McLain JL, Steigerwalt ES, Broughton R, Slaten BL, Mills G (2001) Photogeneration of silver particles in PVA fibers and films. J Cluster Sci 12:457–471
Hebeish AA, El-Rafie MH, Abdel-Mohdy FA, Abdel-Halim ES, Emam HE (2010) Carboxymethyl cellulose for green synthesis and stabilization of silver nanoparticles. Carbohydr Polym 82:933–941
Hong KH (2007) Preparation and properties of electrospun poly(vinyl alcohol)/silver fiber web as wound dressings. Polym Eng Sci 47:43–49
Ibrahim AA, Adel A, Wahab ZAE, Kamar M (2011) Utilization of carboxymethyl cellulose based on bean hulls as chelating agent. Synthesis, characterization and biological activity. Carbohydr Polym 83:94–115
Kim CW, Kim DS, Kang SY, Marquez M, Joo YL (2006) Structural studies of electrospun cellulose nanofibers. Polymer 47:5097–5107
Klemm D, Heublein B, Fink HP, Bohn A (2005) Cellulose: fascinating biopolymer and sustainable raw material. Angew Chem Int Ed 44:3358–3393
Koosha M, Mirzadeh H (2015) Electrospinning, mechanical properties, and cell behavior study of chitosan/PVA nanofibers. J Biomed Mater Res Part A 103A:3081–3093
Kuo PL, Chen WF (2003) Formation of silver nanoparticles under structured amino groups in pseudo dendritic poly (allylamine) derivatives. J Phys Chem B 107:11267–11272
Li H, Xu Y, Xu H, Chang J (2014) Electrospun membranes: control of the structure and structure related applications in tissue regeneration and drug delivery. J Mater Chem B 2:5492–5510
Maneerung T, Tokura S, Rujiravanit R (2008) Impregnation of silver nanoparticles into bacterial cellulose for antimicrobial wound dressing. Carbohydr Polym 72:43–51
Mi HY, Jing X, Salick MR, Cordie TM, Peng XF, Turng LS (2015) Properties and fibroblast cellulast cellular response of soft and hard thermoplastic polyurethane electrospun nanofibrous scaffolds. J Biomed Mater Res B 103:960–970
Miyamal T, Yonezawa Y (2004) Photoinduced formation and aggregation of silver nanoparticles at the surface of carboxymethylcellulose films. J Nanopart Res 6:457–465
Mondal MIH, Yeasmin S, Rahman S (2015) Preparation of food grade carboxymethyl cellulose from corn husk agrowaste. Int J Biol Macromol 79:144–150
Ohkawa K, Cha D, Kim H, Nishida A, Yamamoto H (2004) Electrospinning of chitosan. Macromol Rapid Commun 25:1600–1605
Oun AA, Rhim JW (2015) Preparation and characterization of sodium carboxymethyl cellulose/cotton linter cellulose nanofibril composite films. Carbohydr Polym 127:101–109
Pakravan M, Heuzey MC, Ajji A (2011) A fundamental study of chitosan/PEO electrospinning. Polymer 52:4813–4824
Parikh DV, Fink T, Rajasekharan K, Sachivala ND, Sawhney APS, Calanari TA (2005) Antimicrobial silver/sodium carboxymethyl cotton dressings for burn wounds. Text Res J 75:134–138
Pastroiza-Santos I, Liz-Marzan LM (2002) Formation of PVP-protected metal nanoparticles in DMF. Langmuir 18:2888–2894
Popa M, Pradell T, Crespo D, Calderón-Moreno JM (2007) Stable silver colloidal dispersions using short chain polyethylene glycol. Colloid Surface A 303:184–190
Quan SL, Kang SG, Chin IJ (2010) Characterization of cellulose fibers electrospun using ionic liquid. Cellulose 17:223–230
Rangari VK, Mohammad GM, Jeelani S, Hundley A, Vig K, Singh SR, Pillai S (2010) Synthesis of Ag/CNT hybrid nanoparticles and fabrication of their Nylon-6 polymer nanocomposite for antimicrobial applications. Nanotechnology 21:1–11
Sakai HK (2009) Preparation of highly dispersed core/shell-type titania nanocapsules containing a single Ag nanoparticle. J Am Chem Soc 128:4944–4945
Samatham R, Kim KJ (2006) Electric current as a control variable in the electrospinning process. Polym Eng Sci 46:954–959
Schiffman JD, Schauer CL (2007) Cross-linking chitosan nanofibers. Biomacromolecules 8:594–601
Shameli K, Ahmad MB, Yunus WMZW, Rustaiyan A, Ibrahim NA, Zargar M, Abdollahi Y (2010) Green synthesis of silver/montmorillonite/chitosan bionanocomposites using the UV irradiation method and evaluation of antibacterial activity. Int J Nanomed 5:875–887
Song JL, Birbach NL, Hinestroza JP (2012) Deposition of silver nanoparticles on cellulose fibers via stabilization of carboxymethyl groups. Cellulose 19:411–412
Vasimalai N, John SA (2013) Biopolymer capped silver nanoparticles as fluorophore for ultrasensitive and selective determination of malathion. Talanta 115:24–31
Walker M, Hobot J, Newman GR, Bowler P (2003) Scanning electron microscopic examination of bacterial immobilisation in a carboxymethyl cellulose (AQUACEL®) and alginate dressings. Biomaterials 24:883–890
Zou XQ, Bao HF, Guo HW, Zhang L, Qi L, Jiang JG, Niu L, Dong SJ (2006) Mercaptoethane sulfonate protected, water-soluble gold and silver nanoparticles: syntheses, characterization and their building multilayer films with polyaniline via ion-dipole interactions. J Colloid Interf Sci 295:401–408
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
SHI, D., WANG, F., LAN, T. et al. Convenient fabrication of carboxymethyl cellulose electrospun nanofibers functionalized with silver nanoparticles. Cellulose 23, 1899–1909 (2016). https://doi.org/10.1007/s10570-016-0918-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10570-016-0918-x