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PET/CT Colonography for the Preoperative Evaluation of the Colon Proximal to the Obstructive Colorectal Cancer

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Diseases of the Colon & Rectum

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Abstract

Purpose

This study was designed to evaluate the usefulness of 18-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) colonography in preoperative diagnosis of the tumors proximal to obstructive colorectal cancers, which were defined as cancers that cannot be traversed colonoscopically.

Methods

A whole-body PET/CT protocol for tumor staging and a protocol for CT colonography were integrated into one examination. No cathartic bowel preparation was used before this examination. Thirteen prospective patients with obstructive cancer were examined. We compared the detection rates for obstructive colorectal cancers and tumors proximal to the obstruction using air-inflated PET/CT colonography to intraoperative examinations, histopathologic outcome, and follow-up colonoscopy.

Results

PET/CT colonography correctly identified all 13 primary obstructive colorectal cancers and all 2 synchronous colon cancers proximal to the obstruction. The two synchronous colon cancers detected at PET/CT colonography were confirmed and removed at single-stage surgical procedures. PET/CT colonography was able to localize all colorectal cancers precisely. There were no false-negative or false-positive proximal colorectal cancers by PET/CT colonography. Other preoperative examinations missed the synchronous colon cancers.

Conclusions

In patients with obstructive colorectal cancers, preoperative PET/CT colonography provided valuable anatomic and functional information of the entire colon to properly address surgery of colorectal cancer.

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Acknowledgments

The authors thank Tsukasa Ichinose, R.T. and Ms. Masako Kitatani for assistance.

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Authors and Affiliations

  1. Digestive Disease Center, Showa University Northern Yokohama Hospital, 35-1 Chigasaki-chuo, Tsuzuki-ku, Yokohama, 224-8503, Japan

    Koichi Nagata M.D., Shungo Endo M.D. & Shin-ei Kudo M.D.

  2. Department of Radiology, Tokyo-west Tokushukai Hospital, Tokyo, Japan

    Yoshiko Ota M.D. & Tomohiko Okawa M.D.

Authors
  1. Koichi Nagata M.D.
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  2. Yoshiko Ota M.D.
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  3. Tomohiko Okawa M.D.
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  4. Shungo Endo M.D.
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  5. Shin-ei Kudo M.D.
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Correspondence to Koichi Nagata M.D..

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Nagata, K., Ota, Y., Okawa, T. et al. PET/CT Colonography for the Preoperative Evaluation of the Colon Proximal to the Obstructive Colorectal Cancer. Dis Colon Rectum 51, 882–890 (2008). https://doi.org/10.1007/s10350-008-9236-1

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  • DOI: https://doi.org/10.1007/s10350-008-9236-1

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