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Amperometric nonenzymatic glucose sensor based on a glassy carbon electrode modified with a nanocomposite made from nickel(II) hydroxide nanoplates and carbon nanofibers

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Abstract

We report on a highly sensitive and selective nonenzymatic glucose sensor based on a glassy carbon electrode modified with a composite prepared from nickel(II) hydroxide nanoplates and carbon nanofibers. The nanocomposite was characterized by scanning electron microscopy and powder X-ray diffraction. Electrodes modified with pure Ni(OH)2 and with the nanocomposite were characterized by electrochemical impedance spectroscopy. Cyclic voltammetric and amperometric methods were used to investigate the catalytic properties of the modified electrodes for glucose electrooxidation in strongly alkaline solution. The sensor exhibits a wide linear range (from 0.001 to 1.2 mM), a low detection limit (0.76 μM), fast response time (< 5 s), high sensitivity (1038.6 μA · mM−1 · cm−2), good reproducibility, and long operational stability. Application of the nonenzymatic sensor for monitoring glucose in real samples was also demonstrated.

We report on a highly sensitive and selective nonenzymatic glucose sensor based on a glassy carbon electrode modified with a nanocomposite prepared from nickel (II) hydroxide nanoplates and carbon nanofibers. The facile preparation, high electrocatalytic activity, relatively fast response, favorable reproducibility and long-term performance stability demonstrate the potential applications of the sensor.

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Acknowledgement

The authors thank the National Natural Science Foundation of China (21001004) and Innovation experiment program for Anhui Normal University students (cxsy10022, cxsy11085) for the financial supports.

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Authors and Affiliations

  1. College of Chemistry and Materials Science, Anhui Key Laboratory of Functional Molecular Solids, Anhui Normal University, Wuhu, 241000, People’s Republic of China

    Li Zhang, Sheng-mei Yuan & Xiao-jing Lu

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  1. Li Zhang
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  2. Sheng-mei Yuan
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  3. Xiao-jing Lu
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Correspondence to Li Zhang.

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Zhang, L., Yuan, Sm. & Lu, Xj. Amperometric nonenzymatic glucose sensor based on a glassy carbon electrode modified with a nanocomposite made from nickel(II) hydroxide nanoplates and carbon nanofibers. Microchim Acta 181, 365–372 (2014). https://doi.org/10.1007/s00604-013-1123-3

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  • DOI: https://doi.org/10.1007/s00604-013-1123-3

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