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Nonenzymatic sensing of glucose at neutral pH values and low working potential using a glassy carbon electrode modified with platinum-iron alloy nanoparticles on a carbon support

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Abstract

Alloy nanoparticles of the type PtxFe (where x is 1, 2 or 3) were synthesized by coreduction with sodium borohydride in the presence of carbon acting as a chemical support. The resulting nanocomposites were characterized by scanning electron microscopy and X-ray diffraction. The nanocomposite was placed on a glassy carbon electrode, and electrochemical measurements indicated an excellent catalytic activity for the oxidation of glucose even a near-neutral pH values and at a working voltage as low as 50 mV (vs. SCE). Under optimized conditions, the sensor responds to glucose in the 10.0 μM to 18.9 mM concentration range and with a 3.0 μM detection limit (at an S/N ratio of 3). Interferences by ascorbic acid, uric acid, fructose, acetamidophenol and chloride ions are negligible.

Nonenzymatic sensing of glucose is demonstrated at neutral pH values and low working potential using a glassy carbon electrode modified with platinum-iron alloy nanoparticles on a carbon support.

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Acknowledgments

We acknowledge financial support from the National Natural Science Foundation of China through a project entitled “The synthesis of Pt-M/C nanoparticles and construction of non-enzymatic electrochemical biosensor” (Grant No. 21205030), and by the Science and Technology Department of Hubei province through a project entitled “The development of electrochemical biosensor based on non-noble metal nanocomposites”(2014CFB548), and by State Key Laboratory of Advanced Technology for Materials Synthesis and Processing (Wuhan University of Technology,2015-KF-13), and from the Natural Science Fund for Creative Research Groups of Hubei Province of China through a project entitled “Controllable Synthesis and Application of Nano-/microsized Functional Materials”(2014CFA015).

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Authors and Affiliations

  1. Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials & Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Ministry of Education & College of Chemistry & Chemical Engineering, Hubei University, Wuhan, 430062, China

    He Mei, Qu Sheng, Huimin Wu, Xiuhua Zhang, Shengfu Wang & Qinghua Xia

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  1. He Mei
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  2. Qu Sheng
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  3. Huimin Wu
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  4. Xiuhua Zhang
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  5. Shengfu Wang
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  6. Qinghua Xia
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Correspondence to Huimin Wu.

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Mei, H., Sheng, Q., Wu, H. et al. Nonenzymatic sensing of glucose at neutral pH values and low working potential using a glassy carbon electrode modified with platinum-iron alloy nanoparticles on a carbon support. Microchim Acta 182, 2395–2401 (2015). https://doi.org/10.1007/s00604-015-1580-y

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  • DOI: https://doi.org/10.1007/s00604-015-1580-y

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