Skip to main content

Advertisement

Log in

A 16-year-old male with gynecomastia and ductal carcinoma in situ

  • Case Report
  • Published:
Pediatric Surgery International Aims and scope Submit manuscript

Abstract

While gynecomastia is common in adolescents, male breast cancer in the pediatric population is exceedingly rare. Occasional reports describe malignant and pre-malignant lesions in mastectomy specimens for gynecomastia in young adults. We present a 16-year-old male with unilateral gynecomastia discovered to have ductal carcinoma in situ (DCIS), treated by mastectomy with 4 year follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Fodor PB (1989) Breast cancer in a patient with gynecomastia. Plast Reconstr Surg 84:976–979

    Article  PubMed  CAS  Google Scholar 

  2. Wadie GM, Banever GT, Moriarty KP, Courtney RA, Boyd T (2005) Ductal carcinoma in situ in a 16-year-old adolescent boy with gynecomastia: a case report. J Pediatr Surg 40:1349–1353. doi:10.1016/j.jpedsurg.2005.05.026

    Article  PubMed  Google Scholar 

  3. Cakan N, Kamat D (2007) Gynecomastia: evaluation and treatment recommendations for primary care providers. Clin Pediatr 46:487–490. doi:10.1177/0009922806294800

    Article  Google Scholar 

  4. Wiesman IM, Lehman JA, Parker MG et al (2004) Gynecomastia: an outcome analysis. Ann Plast Surg 53:97–101. doi:10.1097/01.sap.0000116256.01831.17

    Article  PubMed  Google Scholar 

  5. Al-Qattan M, Hassanain J, Mahmoud S et al (2005) On the neglected entity of unilateral gynecomastia. Ann Plast Surg 55:255–257. doi:10.1097/01.sap.0000171681.92825.21

    Article  PubMed  CAS  Google Scholar 

  6. Diamantopoulos S, Bao Y (2007) Gynecomastia and premature thelarche: a guide for practitioners. Pediatr Rev 28:e57–e68. doi:10.1542/pir.28-9-e57

    Article  PubMed  Google Scholar 

  7. Olsson H, Bladstrom A, Alm P (2002) Male gynecomastia and risk for malignant tumors—a cohort study. BMC Cancer 2:26. doi:10.1186/1471-2407-2-26

    Article  PubMed  CAS  Google Scholar 

  8. Cutuli B, Dilhuydy JM, De Lafontan B et al (1997) Ductal carcinoma in situ of the male breast analysis of 31 cases. Eur J Cancer 33:35–38. doi:10.1016/S0959-8049(96)00436-4

    Article  PubMed  CAS  Google Scholar 

  9. Staerkle RF, Lenzlinger PM, Suter SL, Varga Z, Melcher GA, Melcher A (2006) Synchronous bilateral ductal carcinoma in situ of the male breast associated with gynecomastia in a 30-year-old patient following repeated injections of stanozolol. Breast Cancer Res Treat 97:173–176. doi:10.1007/s10549-005-9107-6

    Article  PubMed  Google Scholar 

  10. Liao EC, Kish JB, Hertl MC (2007) Incidental discovery of bilateral breast cancer in a 24-year-old man presenting with gynecomastia. Ann Plast Surg 58:673–676. doi:10.1097/01.sap.0000245118.98550.cf

    Article  PubMed  CAS  Google Scholar 

  11. Hartman AW, Magrish P (1955) Carcinoma of breast in children; case report: six-year-old boy with adenocarcinomas. Ann Surg 141:792–798

    PubMed  CAS  Google Scholar 

  12. Simpson JS, Barson AJ (1969) Breast tumours in infants and children: a 40-year review of cases at a children’s hospital. Can Med Assoc J 101:100–102

    PubMed  CAS  Google Scholar 

  13. Hittmair AP, Lininger RA, Tavassoli FA (1998) Ductal carcinoma in situ (DCIS) in the male breast: a morphologic study of 84 cases of pure DCIS and 30 cases of DCIS associated with invasive carcinoma—a preliminary report. Cancer 83:2139–2149. doi:10.1002/(SICI)1097-0142(19981115)83:10>2139::AID-CNCR12<3.0.CO;2-F

    Article  PubMed  CAS  Google Scholar 

  14. Golshan M, Rusby J, Dominguez F, Smith BL (2007) Breast conservation for male breast carcinoma. Breast 16:653–656. doi:10.1016/j.breast.2007.05.012

    Article  PubMed  Google Scholar 

  15. Pappo I, Wasserman I, Halevy A (2005) Ductal carcinoma in situ of the breast in men: a review. Clin Breast Cancer 6:310–314

    Article  PubMed  CAS  Google Scholar 

  16. Hado HS, Helmy SW, Klemm K, Miller P, Elhadd TA (2003) XX male: a rare cause of short stature, infertility, gynaecomastia and carcinoma of the breast. Int J Clin Pract 57:844–845

    PubMed  CAS  Google Scholar 

  17. Bernard-Gallon DJ, Dechelotte PJ, Le Corre L, Vissac-Sabatier C, Favy DA, Cravello L et al (2003) Expression of BRCA1 and BRCA2 in male breast cancers and gynecomastias. Anticancer Res 23:661–667

    PubMed  CAS  Google Scholar 

  18. Bernard-Gallon DJ, Dechelotte PJ, Le Corre L, Chalabi N, Vissac-Sabatier C, Bignon YJ (2004) Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia. Anticancer Res 24:321–324

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Allan M. Goldstein.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chang, H.L., Kish, J.B., Smith, B.L. et al. A 16-year-old male with gynecomastia and ductal carcinoma in situ. Pediatr Surg Int 24, 1251–1253 (2008). https://doi.org/10.1007/s00383-008-2246-1

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00383-008-2246-1

Keywords

Navigation