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Streptococcus suis biofilm: regulation, drug-resistance mechanisms, and disinfection strategies

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Abstract

Streptococcus suis (S. suis) is a major swine pathogen and an important zoonotic agent. Like most pathogens, the ability of S. suis to form biofilms plays a significant role in its virulence and drug resistance. A better understanding of the mechanisms involved in biofilm formation by S. suis as well as of the methods to efficiently remove and kill biofilm-embedded bacteria can be of high interest for the prevention and treatment of S. suis infections. The aim of this literature review is to update our current knowledge of S. suis biofilm formation, regulatory mechanisms, drug-resistance mechanisms, and disinfection strategies.

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Funding

This study was funded by the National Key Research and Development Program of China (2018YFD0500100), the National Natural Science Foundation of China (31772761, 31540095), the Science and Technology Development Project of Henan Province (182300410047, 162300410067), and the China Scholarship Council (CSC).

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Correspondence to Yang Wang or Li Yi.

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The authors declare that they have no conflict of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Wang, Y., Wang, Y., Sun, L. et al. Streptococcus suis biofilm: regulation, drug-resistance mechanisms, and disinfection strategies. Appl Microbiol Biotechnol 102, 9121–9129 (2018). https://doi.org/10.1007/s00253-018-9356-z

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  • DOI: https://doi.org/10.1007/s00253-018-9356-z

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