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Bench to batch: advances in plant cell culture for producing useful products

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Abstract

Despite significant efforts over nearly 30 years, only a few products produced by in vitro plant cultures have been commercialized. Some new advances in culture methods and metabolic biochemistry have improved the useful potential of plant cell cultures. This review will provide references to recent relevant reviews along with a critical analysis of the latest improvements in plant cell culture, co-cultures, and disposable reactors for production of small secondary product molecules, transgenic proteins, and other products. Some case studies for specific products or production systems are used to illustrate principles.

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Acknowledgments

Support was provided in part by the Arkansas Biosciences Institute, the major research component of the Arkansas Tobacco Settlement Proceeds Act of 2000.

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Authors and Affiliations

  1. Department of Biology and Biotechnology at Gateway, Worcester Polytechnic Institute, 100 Institute Rd, Worcester, MA, 01609, USA

    Pamela J. Weathers & Melissa J. Towler

  2. Arkansas Bioscience Institute, also College of Agriculture, Arkansas State University, Jonesboro, AR, 72467, USA

    Jianfeng Xu

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  1. Pamela J. Weathers
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  2. Melissa J. Towler
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  3. Jianfeng Xu
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Correspondence to Pamela J. Weathers.

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Weathers, P.J., Towler, M.J. & Xu, J. Bench to batch: advances in plant cell culture for producing useful products. Appl Microbiol Biotechnol 85, 1339–1351 (2010). https://doi.org/10.1007/s00253-009-2354-4

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