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Scale-Up Production of Bioactive Compounds Using Bioreactors

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Nutraceuticals Production from Plant Cell Factory

Abstract

The increased demand for plant secondary metabolites by the pharmaceutical, food, flavor, beverage, and cosmetic industries has necessitated the rapid and mass production of these metabolites using in vitro plant culture systems. Bioreactors provided a suitable alternative to conventional plant culture by facilitating large-scale propagation of plants and production of secondary metabolites. Bioreactors proved to be effective plant culture systems which are genetically stable, low cost, easy to operate, and fully automated. Bioreactors play a very important role in medicinal plant industry and have evolved over time. At present, a variety of bioreactor configurations are available each customized for specific plant cell/tissue so that a stable optimum yield of bioactives is obtained. The chapter discusses briefly about the use of bioreactors in scaling up the production of secondary metabolites, different categories and designs of bioreactors available, factors on which bioreactor function depends, and the different crops in which bioreactor scaling up is attempted.

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Authors and Affiliations

  1. Indian Institute of Horticultural Research, Bengaluru, India

    M. R. Rohini & P. E. Rajasekharan

Authors
  1. M. R. Rohini
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  2. P. E. Rajasekharan
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Editors and Affiliations

  1. Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China

    Tarun Belwal

  2. Institute of Microbiology, Bulgarian Academy of Sciences, Plovdiv, Bulgaria

    Milen I. Georgiev

  3. Agricultural Biotechnology, King Faisal University, Al-Hassa, Saudi Arabia

    Jameel M Al-Khayri

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Rohini, M.R., Rajasekharan, P.E. (2022). Scale-Up Production of Bioactive Compounds Using Bioreactors. In: Belwal, T., Georgiev, M.I., Al-Khayri, J.M. (eds) Nutraceuticals Production from Plant Cell Factory. Springer, Singapore. https://doi.org/10.1007/978-981-16-8858-4_3

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