Zusammenfassung
Aufgrund der gestiegenen Anzahl an Wirbelsäuleneingriffen und insbesondere Spondylodesen, zunehmend auch bei alten oder immunsupprimierten Patienten, werden Wirbelsäulenchirurgen immer häufiger mit dem Problem tiefer Wundinfektionen und/oder Spondylodiszitis bei einliegendem Instrumentarium konfrontiert. Diese teils lebensbedrohlichen Komplikationen stellen den behandelnden Arzt oftmals vor erhebliche Schwierigkeiten, nicht nur in der Diagnostik sondern auch in der operativen Strategiefindung, denn nicht selten ist eine Vielzahl von Eingriffen notwendig, bevor der Infektionsherd saniert ist. Das Ziel dieser Arbeit ist, einen möglichen Algorithmus bzgl. Diagnostik und Therapie zur Beherrschung solcher teils hartnäckiger Infektionen darzustellen.
Abstract
Due to a significant increase in spinal interventions and in particular spinal fusion procedures, also in elderly and immunocompromised patients, spinal surgeons are increasingly confronted with deep wound infections and/or spondylodiscitis with in situ instrumentation. This occasionally life-threatening complication can be a challenge for even the most experienced physician, not only in the initial diagnosis but also when determining the operative treatment strategy. It is not uncommon that patients must undergo several operations before a deep infection is finally under control. The aim of this article is to suggest an algorithm for the diagnostics and management of this very troubling complication.
Literatur
Bassewitz H, Herkowitz H (2001) Lumbar stenosis with spondylolisthesis: current concepts of surgical treatment. Clin Orthop Relat Res 384:54–60
Boos N (2008) Infections of the spine. In: Boos N, Aebi M (eds) Spinal disorders. Springer, Berlin Heidelberg New York, pp 1021–1037
Chaudhary SB, Vives MJ, Basra SK, Reiter MF (2007) Postoperative spinal wound infections and postprocedural diskitis. J Spinal Cord Med 30:441–451
Curry WT, Ghogawala Z, Gollogly S, Brodke D (2005) Postoperative Imaging. In: Benzel EC (ed) Spine surgery – techniques, complication avoidance, and management. Churchill Livingstone, New York, pp 1768–1777
Dagirmanjian A, Schils J, McHenry M, Modic MT (1996) MR Imaging of vertebral osteomyelitis revisited. Am J Roentgenol 167:1539–1543
Eysel P, Peters K (1995) Spondylodiscitis. In: Peters K, Klosterhafen B (Hrsg) Bakterielle Infektionen der Knochen und Gelenke. Enke, Stuttgart
Frangen TM, Kälicke T, Gottwald M et al (2006) Surgical management of spondylodiscitis. An analysis of 78 cases. Unfallchirurg 109:743–753
Gemmel F, Dumarey N, Palestro CJ (2006) Radionuclide imaging of spinal infections. Eur J Nucl Med Mol Imaging 33:1226–1237
Glassman SD, Dimar JR, Puno RM, Johnson JR (1996) Salvage of instrumented lumbar fusions complicated by surgical wound infection. Spine 21:2163–2169
Hsieh MK, Chen LH, Niu CC et al (2011) Postoperative anterior spondylodiscitis after posterior pedicle screw instrumentation. Spine J 11:24–29
Isenberg J, Jubel A, Hahn U et al (2005) Multistep surgery treatment concept of destructive spondylodiscitis in patients with reduced general condition. Orthopade 34:159–166
Kraft CN, Krüger T, Westhoff J et al (2011) CRP and leukocyte-count after lumbar spine surgery: fusion vs. nucleotomy. Acta Orthop 82:489–493
Levi AD, Dickman CA, Sonntag VK (1997) Management of postoperative infections after spinal instrumentation. J Neurosurg 86:975–980
Mehbod AA, Ogilvie JW, Pinto MR et al (2005) Postoperative deep wound infections in adults after spinal fusion – management with vacuum-assisted wound closure. J Spinal Disord Tech 28:14–17
Mirovsky Y, Floman Y, Smorgick Y et al (2007) Management of deep wound infection after posterior lumbar interbody fusion with cages. J Spinal Disord Tech 20:127–131
Mückley T, Kirschner M, Hierholzer C, Hofmann GO (2003) Spondylitis – Spondylodiszitis. Neue Therapiekonzepte. Trauma Berufskrankh 5:S296–S304
Picada R, Winter RB, Lonstein JE (2000) Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation: incidence and management. J Spinal Disord 13:42–45
Rieneck K, Hansen SE, Karle A, Gutschik E (1996) Microbiologically verified diagnosis of infectious spondylitis using CT-guided fine needle biopsy. APMIS 104:755–762
Robinson Y, Tschoeke SK, Kayser R et al (2009) Reconstruction of large defects in vertebral osteomyelitis with expandable titanium cages. Int Orthop 33:745–749
Rohmiller MT, Akbarnia BA, Raiszadeh K et al (2010) Closed suction irrigation for the treatment of postoperative wound infections following posterior spinal fusion and instrumentation. Spine [Epub ahead of print]
Schmitz A, Risse JH, Grunwald F et al (2001) Fluorine-18-fluorodeoxyglucose positron emission tomography findings in spondylodiscitis: preliminary results. Eur Spine J 10:534–539
Sehn JK, Gilula LA (2011) Percutaneous needle biopsy in diagnosis and identification of causative organisms in cases of suspected vertebral osteomyelitis. Eur J Radiol [Epub ahead of print]
Shibayama M, Nagahara M, Kawase G et al (2010) New needle biopsy technique for lumbar pyogenic spondylodiscitis. Spine 35:E1347–E1349
Sobottke R, Eysel P (2008) Spondylitis and spondylodiscitis. In: Käfer W, Cakir B, Mattes T, Reichel H (eds) Orthopaedic spine surgery. Steinkopff, Heidelberg, pp 169–185
Thalgott JS, Cotler HB, Sasso RC et al (1991) Postoperative infections in spinal implants. Classification and analysis – a multicenter study. Spine 16:981–984
Tokuhashi Y, Ajiro Y, Umezawa N (2008) Conservative follow-up after epidural abscess and discitis complicating instrumented metal interbody cage. Orthopedics 31:611
Tyrrell PN, Cassar-Pullicino VN, McCall IW (1999) Spinal infection. Eur Radiol 9:1066–1077
Walter J, Kuhn SA, Reichart R et al (2010) PEEK cages as a potential alternative in the treatment of cervical spondylodiscitis: a preliminary report on a patient series. Eur Spine J 19:1004–1009
Weinstein MA, McCabe JP, Cammissa FP Jr (2000) Postoperative spinal wound infection: a review of 2391 consecutive index procedures. J Spinal Disord 13:422–426
Yang SC, Fu TS, Chen LH et al (2008) Identifying pathogens of spondylodiscitis: percutaneous endoscopy or CT-guided biopsy. Clin Orthop Relat Res 466:3086–3092
Young PM, Berquist TH, Bancroft LW, Peterson JJ (2007) Complications of spinal instrumentation. RadioGraphics 27:775–789
Interessenkonflikt
Keine Angabe.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kraft, C., Fell, M. Algorithmus zur Behandlung tiefer Wirbelsäuleninfektionen und der Spondylodiszitis bei einliegender Instrumentierung. Orthopäde 41, 51–57 (2012). https://doi.org/10.1007/s00132-011-1841-3
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00132-011-1841-3