Skip to main content
Log in

Die rheumatisch bedingte Instabilität der oberen Halswirbelsäule

Instability of the upper cervical spine due to rheumatism

  • Leitthema
  • Published:
Der Orthopäde Aims and scope Submit manuscript

Zusammenfassung

Mit einem Befall der Halswirbelsäule (HWS) beim Rheumatiker ist im Langzeitverlauf in >50% der Fälle zu rechnen. Primär kommt es zu einer Manifestation des rheumatischen Geschehens an der oberen HWS. Der initiale Befall des Segments C1/C2 führt zu einer horizontalen Instabilität, bei fortschreitender Destruktion kann es zu einer sog. vertikalen Instabilität kommen. Diese ist durch ein relatives Höhertreten des Dens gekennzeichnet. Daraus resultiert die Gefahr einer Myelonkompression mit der Ausbildung der prognostisch ungünstigsten Komplikation der rheumatischen Arthritis an der HWS, der zervikalen Myelopathie.

Ziel der Therapie des Rheumatikers muss es sein, diese Veränderungen in der Frühphase zu erfassen, zu kontrollieren und zu therapieren. Bei progredienter Instabilität, bei therapieresistenten Beschwerden und bei neurologischen Defiziten machen sich operative stabilisierende Maßnahmen erforderlich. Diese sind in der Lage, das Fortschreiten der Destruktionen aufzuhalten und verbessern die Prognose des Rheumatikers hinsichtlich der Schmerzen, der neurologischen Defizite und nicht zuletzt der Lebenserwartung.

Abstract

Rheumatic manifestation at the cervical spine occurs in more than 50% of all cases in the natural course of this disease. The first cervical manifestation takes place in the upper cervical spine. The initial involvement of the C1/C2 segment leads to atlantodental subluxation. Progressive destruction can result in vertical instability, which is characterized by cranial subluxation of the odontoid process with the danger of resulting stenosis and cervical myelopathy.

The goal of diagnosis has to be the early recognition of these changes to establish an effective treatment protocol. Persistent pain, neurological deficits, and progressive radiological signs for instability are indications for operative stabilizing procedures. These procedures avoid progressive destruction and improve the prognosis regarding pain decrease, regression of neurological deficits, and life expectancy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5
Abb. 6
Abb. 7
Abb. 8
Abb. 9
Abb. 10
Abb. 11

Literatur

  1. Abumi K, Shono Y, Taneichi H, Ito M, Kaneda K (1999) Correction of cervical kyphosis using pedicle srew fixation systems. Spine 24: 2389–2396

    Article  PubMed  Google Scholar 

  2. Abumi K, Takada T, Shono Y, Kaneda K, Fujiya M (1999) Posterior occipitocervical reconstruction using cervical pedicle screws and plate-rod systems. Spine 24: 1425–1434

    Article  PubMed  Google Scholar 

  3. Abumi K, Shono Y, Ito M, Taneichi H, Kotani Y, Kaneda K (2000) Complications of pedicle screw fixation in reconstructive surgery of the cervical spine. Spine 25: 962–969

    Article  PubMed  Google Scholar 

  4. Arlt AC, Steinmetz J (2004) Die zervikale Myelopathie als Komplikation der rheumatoiden Arthritis. Z Rheumatol 63: 281–295

    Article  PubMed  Google Scholar 

  5. Babí-Naglic D, Potocki K, Curkovic B (1999) Clinical and radiological features of atlantoaxial joints in rheumatoid arthritis. Z Rheumatol 58: 196–200

    Article  PubMed  Google Scholar 

  6. Blauth M, Richter M, Lange U (1999) Transartikuläre Verschraubung C1/2 bei atlanto-axialer Instabilität. Orthopäde 28: 651–661

    Google Scholar 

  7. Boden S, Dodge L, Bohlmann H, Rechtine G (1993) Rheumatoid arthritis of the cervical spine. J Bone Joint Surg Am 75: 1282–1297

    PubMed  Google Scholar 

  8. Börm W, König RW, Albrecht A, Richter HP, Kast E (2004) Percutaneous transarticular atlantoaxial screw fixation using a cannulated screw system and image guidance. Minim Invas Neurosurg 47: 111–114

    Article  Google Scholar 

  9. Brooks AL, Jenkins EG (1978) Atlanto-axial arthrodesis by the wedge compression method. J Bone Joint Surg Am 60: 279–284

    PubMed  Google Scholar 

  10. Bouchard-Chabot A, Frédéric L (2002) Cervical spine involvement in rheumatoid arthritis. A review. Joint Bone Spine 69: 141–154

    Article  PubMed  Google Scholar 

  11. Castro HM, Jerosch J (Hrsg) (1996) Orthopädisch-traumatologische Wirbelsäulen-und Beckendiagnostik. Enke, Stuttgart

  12. Cornefjord M, Henriques T, Alemany M, Olerud C (2003) Posterior atlanto-axial fusion with the Olerud cervical fixation system for odontoid fractures and C1-C2 instability in rheumatoid arthritis. Eur Spine J 12: 91–96

    PubMed  Google Scholar 

  13. Christensson D, Saveland H, Zygmunt S, Jonsson K, Rydholm U (1999) Cervical laminectomy without fusion in patients with rheumatoid arthritis. J Neurosurg 90 [Suppl 2]: 186–190

    PubMed  Google Scholar 

  14. Christensson D, Saveland H, Rydholm U (2000) Cervical spine surgery in rheumatoid arthritis: a Swedish nation-wide registration of 83 patients. Scand J Rheumatol 29: 314–319

    Article  PubMed  Google Scholar 

  15. Coyne TJ, Fehlings MG, Wallace MC, Bernstein M, Tator C (1995) C1-C2 posterior cervical fusion: long-term evaluation of results and efficacy. Neurosurgery 37: 688–693

    PubMed  Google Scholar 

  16. Crockard HA, Pozo JL, Ransford AO, Stevens JM, Kendall BE, Essigman WK (1986) Transoral decompression and posterior fusion for rheumatoid atlanto-axial subluxation. J Bone Joint Surg Br 68: 350–356

    PubMed  Google Scholar 

  17. Dickmann CA, Foley KT, Sonntag VK, Smith MM (1959) Cannulated screws for odontoid screw fixation and atlantoaxial transarticular screw fixation. Technical note. J Neurosurg 83: 1095–1100

    Google Scholar 

  18. Dvorak J, Grob D, Baumgartner H, Gschwend N, Grau EW, Larsson S (1989) Functional evaluation of the spinal cord by magnetic resonance imaging in patients with rheumatoid arthritis and instability of the upper cervical spine. Spine 14: 1057–1064

    PubMed  Google Scholar 

  19. Ebraheim NA, Klausner T, Xu R, Yeasting RA (1998) Safe lateral-mass screw lengths in the Roy-Camille and Magerl techniques: an anatomic study. Spine 23: 1739–1742

    Article  PubMed  Google Scholar 

  20. El Shagir H, Böhm H, Greiner-Perth R (2005) Mini-open approach combined with percutaneous transarticular screw fixation for C1-C2 fusion. Neurosurg Rev 28: 59–63

    PubMed  Google Scholar 

  21. Falope ZF, Griffiths ID, Platt PN, Todd NV (2002) Cervical myelopathy and rheumatoid arthritis: a retrospective analysis of management. Clin Rehabil 16: 625–629

    Article  PubMed  Google Scholar 

  22. Farey ID, Nadkarni S, Smith N (1999) Modified Gallie technique versus transarticular screw fixation in C1–C2 fusion. Clin Orthop 359: 126–135

    Article  PubMed  Google Scholar 

  23. Fielding JW, Cochran GVB, Lawsing JF III, Hohl M (1974) Tears of the transverse ligament of the atlas: a clinical and biomechanical study. J Bone Joint Surg Am 56: 1683–1691

    PubMed  Google Scholar 

  24. Fujiwara K, Fujimoto M, Owaki H, Kono J, Nakase T (1998) Cervical lesion related to the systemic progression in rheumatoid arthritis. Spine 23: 2052–2056

    Article  PubMed  Google Scholar 

  25. Galli WE (1939) Fractures and dislocations of the cervical spine. Am J Surg 46: 495–499

    Article  Google Scholar 

  26. Goffin J, Brussel KV, Martens K, Sloten JV, Audekercke RV, Smet MH (2001) Three-dimensional computed tomography-based personalized drill guide for posterior cervical stabilization at C1–C2. Spine 26: 1343–1347

    Article  PubMed  Google Scholar 

  27. Göttsche T, Kothe R, Adam G, Rüther W (2004) Radiologische Diagnostik der zervikalen rheumatoiden Arthritis. Z Rheumatol 63: 296–302

    PubMed  Google Scholar 

  28. Greenspan A (1993) Skelettradiologie: Orthopädie, Traumatologie, Rheumatologie, Onkologie. VCH Verlagsgesellschaft, Weinheim

  29. Grob D, Magerl F (1987) Dorsale Spondylodese der Halswirbelsäule mit der Hakenplatte. Orthopäde 16: 55–61

  30. Grob D, Crisco JJ, Panjabi MM, Wang P, Dvorak J (1991) Biomechanical evaluation of four different posterior atlantoaxial fixations techniques. Spine 17: 480–490

    Google Scholar 

  31. Grob D (1993) Principles of surgical treatment of the cervical spine in rheumatoid arthritis. Eur Spine J 2: 180–190

    Article  Google Scholar 

  32. Grob D, Würsch R, Grauer W, Sturzenegger J, Dvorak J (1997) Atlantoaxial fusion and retrodental pannus in rheumatoid arthritis. Spine 22: 1580–1584

    Article  PubMed  Google Scholar 

  33. Grob D (1998) Chirurgische Eingriffe an der Halswirbelsäule bei Polyarthritis: Indikation und Operationsstrategie. Orthopäde 27: 177–181

  34. Grob D (2000) Atlantoaxial immobilization in rheumatoid arthritis: a prophylactic procedure? Eur Spine J 9: 404–409

    Article  PubMed  Google Scholar 

  35. Grob D (2000) Posterior occipitocervical fusion in rheumatoid arthritis and other instabilities. J Orthop Sci 5: 82–87

    Article  PubMed  Google Scholar 

  36. Grob D (2004) Chirurgische Aspekte der rheumatischen Halswirbelsäule. Orthopäde 33: 1201–1212

    Google Scholar 

  37. Halla J, Hardin J (1990) The spectrum of atlantoaxial facet joint involvement in rheumatoid arthritis. Arthritis Rheum 33: 325–329

    PubMed  Google Scholar 

  38. Hanson PB, Montesano PX, Sharkey NA, Rauschning W (1990) Anatomic and biomechanic assessment of transarticular screw fixation for atlantoaxial instability. Spine 16: 173–177

    Google Scholar 

  39. Harms J, Schmelzle R, Stoltze D (1987) Osteosynthesen im occipito-cervicalem Übergang vom transoralen Zugang aus. IN: XVII SICOT World Congress Abstract book. Demeter, München

  40. Harms J, Melcher RP (2001) Posterior C1-C2 fusion with polyaxial screw and rod fixation. Spine 26: 2467–2471

    Article  PubMed  Google Scholar 

  41. Herrmann KG, Bollow M (2004) Magnetic resonance imaging of the axial skeleton in rheumatoid disease. Best Pract Res Clin Rheumatol 18: 881–907

    Article  PubMed  Google Scholar 

  42. Herz T, Franz A, Giaccomuzzi SM, Bale R, Krismer M (2003) Accuracy of spinal navigation for Magerl screws. Clin Orthop 409: 124–130

    PubMed  Google Scholar 

  43. Jun BY (1998) Anatomic study for ideal and safe posterior C1-C2 transarticular screw fixation. Spine 23: 1703–1707

    Article  PubMed  Google Scholar 

  44. Kandziora F, Mittlmeier T, Kerschbaumer F (1999) Stage-related surgery for cervical spine instability in rheumatoid arthritis. Eur Spine J 8: 371–381

    Article  PubMed  Google Scholar 

  45. Kandziora F, Kerschbaumer F, Starker M, Mittlmeier T (2000) Biomechanical assessment of transoral plate fixation for atlantoaxial instability. Spine 25:1555–1561

    Article  PubMed  Google Scholar 

  46. Kauppi M, Neva MH (1998) Sensitivity of lateral view cervical spine radiographs taken in the neutral position in atlantoaxial subluxation in rheumatic diseases. Clin Rheumatol 17: 511–514

    Article  PubMed  Google Scholar 

  47. Kerschbaumer K, Kandziora F, Klein C, Mittlmeier T, Starker M (2000) Transoral decompression, anterior plate fixation, and posterior wire fusion for irreducible atlantoaxial kyphosis in rheumatoid arthritis. Spine 25: 2708–2715

    Article  PubMed  Google Scholar 

  48. Kerschbaumer F, Rittmeister M, Ewald W, Kandziora F (2001) Die atlantoaxiale Kyphose. Orthopäde 30: 919–924

    Google Scholar 

  49. Khanna AJ, Carbone JJ, Kebaish KM, Cohen DB, Riley LH, Wassermann BA, Kostuik JP (2002) Magnetic resonance imaging of the cervical spine: current techniques and spectrum of disease. J Bone Joint Surg Am 84: 70–80

    Article  PubMed  Google Scholar 

  50. Klekamp JW, Ugbo JL, Heller JG, Hutton WC (2000) Cervical transfacet versus lateral mass screws: a biomechanical comparison. J Spinal Disord 13:515–518

    Article  PubMed  Google Scholar 

  51. Kolen ER, Schmidt MH (2002) Rheumatoid arthritis of the cervical spine. Sem Neurol 22: 179–186

    Article  Google Scholar 

  52. Kotani Y, Abumi K, Ito M, Minami A (2003) Improved accuracy of computer-assisted cervical pedicle screw insertion. J Neurosurg (Spine 3) 99: 257–263

  53. Kothe R, Wiesner L, Rüther W (2002) Die rheumatische Halswirbelsäule. Orthopäde 31: 1114–1122

  54. Kothe R, Wiesner L, Rüther W (2004) Therapie der zervikalen rheumatoiden Arthritis. Z Rheumatol 63: 303–311

    Article  PubMed  Google Scholar 

  55. Kraus DR, Peppelmann WC, Agarwal AK, DeLeeuw HW, Donaldson WF (1991) Incidence of subaxial subluxation in patients with generalized rheumatoid arthritis who have had previous occipital cervical fusions. Spine 16: 486–489

    Google Scholar 

  56. Larsen A, Dahle K, Eek M (1977) Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films. Acta Radiol 18: 481–491

    Google Scholar 

  57. Lipson S (1985) Cervical myelopathy and posterior atlanto-axial subluxations in patients with rheumatoid arthritis. J Bone Joint Surg Am 67: 593–597

    PubMed  Google Scholar 

  58. Madawi A, Solanki G, Casey A, Crockard H (1997) Variations of the groove in the axis vertebra for the vertebral artery. J Bone Joint Surg Br 79: 820–823

    Article  PubMed  Google Scholar 

  59. Maeda T, Saito T, Harimaya K, Shuto T, Iwamoto Y (2004) Atlantoaxial instability in neck retraction and protrusion positions in patients with rheumatoid arthritis. Spine 29: 757–762

    Article  PubMed  Google Scholar 

  60. Magerl F, Seemann P (1986) Stable posterior fusion of the atlas and the axis by transarticular screw fixation. In: Kehr P, Weidner A (eds) Cervical spine. Springer, Wien New York, pp 322–327

  61. Matsumoto M, Chiba K, Nakamura M, Ogawa Y, Toyama Y, Ogawa J (2005) Impact of interlaminar graft materials on the fusion status in atlantoaxial transarticular screw fixation. J Neurosurg Spine 2: 23–26

    PubMed  Google Scholar 

  62. Matsunaga S, Onishi T, Sakou T (2001) Significance of occipitoaxial angle in subaxial lesion after occipitocervical fusion. Spine 26: 161–165

    Article  PubMed  Google Scholar 

  63. Matsunaga S, Sakou T (2003) Prognosis of patients with upper cervical lesions caused by rheumatoid arthritis: comparison of occipitocervical fusion between C1 laminectomy and nonsurgical management. Spine 28: 1581–1587

    Article  PubMed  Google Scholar 

  64. McGuire RAJ, Harkey HL (1995) Modification of technique and results of atlantoaxial transfacet stabilization. Orthopedics 18: 1029–1032

    PubMed  Google Scholar 

  65. McRorie GR, McLoughlin P, Russel T, Beggs I, Nuki G, Hurst NP (1996) Cervical surgery in patients with rheumatoid arthritis: an appraisal. Ann Rheum Dis 55: 99–104

    PubMed  Google Scholar 

  66. Mizutani J, Tsubouchi S, Fukuoka M, Otsuka T, Matsui N (2002) Surgical treatment of the rheumatoid cervical spine in patients aged 70 years or older. Rheumatology (Oxford) 41: 910–916

    Google Scholar 

  67. Monsey RD (1997) Rheumatoid arthritis of the cervical spine. J Am Acad Orthop Surg 5: 240–248

    PubMed  Google Scholar 

  68. Morizono Y, Sakou T, Kawaida H (1987) Upper cervical involvement in rheumatoid arthritis. Spine 12: 721–725

    PubMed  Google Scholar 

  69. Moskovich R, Crockard HA (1992) Atlantoaxial arthrodesis using interlaminar clamps: an improved technique. Spine 17: 261–267

    PubMed  Google Scholar 

  70. Narváez JA, Narváez J, Roca Y, Aguilera C (2002) MR imaging assessment of clinical problems in rheumatoid arthritis. Eur Radiol 12: 1819–1828

    Article  PubMed  Google Scholar 

  71. Neva MH, Kaarela K, Kauppi M (2000) Prevalence of radiological changes in the cervical spine-a cross sectional study after 20 years from presentation of rheumatoid arthritis. J Rheumatol 27: 90–93

    PubMed  Google Scholar 

  72. Neva MH, Kauppi M, Kautiainen H, Luukainen R, Hannonen P, Leirisalo-Repo M (2000) Combination drug therapy retards the development of rheumatoid atlantoaxial subluxations. Arthritis Rheum 43: 2397–2401

    Article  PubMed  Google Scholar 

  73. Neva MH, Isomäki P, Hannonnen P, Kauppi M, Krishnan E, Sokka T (2003) Early and extensive erosiveness in peripheral joints predicts atlantoaxial subluxations in patients with rheumatoid arthritis. Arthritis Rheum 48: 1808–1813

    Article  PubMed  Google Scholar 

  74. Neva MH, Kotaniemi A, Kaarela K, Lehtinen JT, Belt EA, Kauppi M (2003) Atlantoaxial disorders in rheumatoid arthritis associate with the destruction of peripheral and shoulder joints, and decreased bone mineral density. Clin Exp Rheumatol 21: 179–184

    PubMed  Google Scholar 

  75. Paimela L, Laasonen L, Kankaanpaa E, Lerisalo-Repo M (1997) Progression of cervical spine changes in patients with early rheumatoid arthritis. J Rheumatol 24: 1280–1284

    PubMed  Google Scholar 

  76. Pellicci PM, Ranawat CS, Tsairis P, Bryan WJ (1981) A prospective study of the progression of rheumatoid arthritis of the cervical spine. J Bone Joint Surg Am 63: 342–350

    PubMed  Google Scholar 

  77. Peppelmann W, Kraus D, Donaldson W, Agarwal A (1993) Cervical spine surgery in rheumatoid arthritis: improvement of neurologic deficit after cervical spine fusion. Spine 18: 2375–2379

    PubMed  Google Scholar 

  78. Rana NA, Hancock DO, Taylor AR, Hill AG (1973) Atlantoaxial subluxation in rheumatoid arthritis. J Bone Joint Surg Br 55: 195–198

    Google Scholar 

  79. Ransford AO, Crockard HA, Pozo JL, Thomas NP, Nelson IW (1986) Craniocervical instability treated by contoured loop fixation. J Bone Joint Surg Br 68: 173–177

    PubMed  Google Scholar 

  80. Redlund-Johnell I, Petterson H (1984) Radiographic measurements of the cranio-vertebral region. Designed for evaluation of abnormalities in rheumatoid arthritis. Acta Radiol Diagn 25: 23–28

    Google Scholar 

  81. Reichel H, Liebhaber A, Babinsky K, Keysser G (2002) Röntgenologische Veränderungen der Halswirbelsäule bei der rheumatoiden Arthritis: prognostische Faktoren an Hand einer Querschnittuntersuchung. Z Rheumatol 61: 710–717

    Article  PubMed  Google Scholar 

  82. Reijnierse M, Bloem J, Dijkmans B, Kroon H, Holscher H, Hansen H, Breedveld FC (1996) The cervical spine in rheumatoid arthritis: relationship between neurological signs and morphology on MR imaging and radiographs. Skeletal Radiol 25: 431–439

    Article  PubMed  Google Scholar 

  83. Reijnierse M, Breedveld F, Kroon HM, Hansen B, Pope TL, Bloem JL (2000) Are magnetic resonance flexion views useful in evaluating the cervical spine patients with rheumatoid arthritis? Skeletal Radiol 29: 85–89

    Article  PubMed  Google Scholar 

  84. Reijnierse M, Dijkmans BAC, Hansen B et al. (2001) Neurological dysfunction in patients with rheumatoid arthritis of the cervical spine. Predictive value of clinical, radiographic and MR imaging parameters. Eur Radiol 11: 467–473

    Article  PubMed  Google Scholar 

  85. Reindl R, Sen M, Aebi M (2003) Anterior instrumentation for traumatic C1-C2 instability. Spine 28: 329–333

    Article  Google Scholar 

  86. Roy-Camille R, Saillant G (1984) Spinal injuries without neurological complications. Int Orthop 8: 155–162

    Article  PubMed  Google Scholar 

  87. Sasso RC, Jeanneret B, Fischer K, Magerl F (1994) Occipitocervical fusion with posterior plate and screw instrumentation. A long-term follow-up study. Spine 15: 2364–2368

    Google Scholar 

  88. Sen MK, Steffen T, Beckman L, Tsantrizos A, Reindl R, Aebi M (2005) Atlantoaxial fusion using anterior transarticular screw fixation of C1-C2: technical innovation and biomechanical study. Eur Spine J 14(5): 512–518

    Article  PubMed  Google Scholar 

  89. Shad A, Sharif SS, Teddy PJ, Cadoux-Hudson TAD (2002) Craniocervical fusion for rheumatoid arthritis: comparison of sublaminar wires and the lateral mass screw craniocervical fusion. Br J Neurosurg 16: 483–486

    Article  PubMed  Google Scholar 

  90. Shen FH, Samartzis D, Jenis LG, An HS (2004) Rheumatoid arthritis: evaluation and surgical management of the cervical spine. Spine J 4: 689–700

    Article  PubMed  Google Scholar 

  91. Seybold EA, Baker JA, Criscitiello AA, Ordway NR, Park CKP, Conolly PJ (1999) Characteristics of unicortical and bicortical lateral mass screws in the cervical spine. Spine 24: 2397–2403

    Article  PubMed  Google Scholar 

  92. Shimizu T, Shimada H, Shirakura K (1993) Scapulohumeral reflex (Shimizu). Its clinical significance and testing maneuver. Spine 18: 2182–2190

    PubMed  Google Scholar 

  93. Stiskal MA, Neuhold A, Szolar DH, Saeed M, Czerny C, Leeb B, Smolen J, Czembirek H (1995) Rheumatoid arthritis of the craniocervical region by MR imaging: detection and characterization. Am J Roentgenol 165: 485–592

    Google Scholar 

  94. Sunahara M, Matsunaga S, Mori T, Ijiri K, Sakou T (1997) Clinical course of conservatively managed rheumatoid arthritis patients with myelopathy. Spine 22: 2603–2608

    Article  PubMed  Google Scholar 

  95. Thabe H (1981) Atlanto-dentale Dislokation bei chronischer Polyarthritis. Korrelation klinischer, bildgebender, neurologischer und elektrophysiologischer Befunde. Z Rheumatol 40: 6–11

    PubMed  Google Scholar 

  96. Thabe H (1997) Praktische Rheumaorthopädie. Chapman & Hall, Weinheim, S 93–108

  97. Torklus von D, Gehle W (1987) Die obere Halswirbelsäule. Thieme, Stuttgart New York

  98. Vaccaro AR, Lehmann AP, Ahlgren BD, Garfin SR. (1999) Anterior C1-C2 screw fixation and bony fusion trough an anterior retropharyngeal approach. Orthopedics 22: 1165–1170

    PubMed  Google Scholar 

  99. van Asselt KM, Lems WF, Bongartz EB, Hamburger HL, Drossaers-Bakker KW, Dijkmans BAC, van Soesbergen RM (2001) Outcome of cervical spine surgery in patients with rheumatoid arthritis. Ann Rheum Dis 60: 448–452

    Article  PubMed  Google Scholar 

  100. Vesela M, Stetkarova I, Lisy J (2005) Prevalence of C1/C2 involvement in Czech rheumatoid arthritis patients, correlation of pain intensity, and distance of ventral subluxation. Rheumatol Int (e-pub)

  101. Weidner A, Wähler M, Chiu ST, Ulrich CG (2000) Modification of C1-C2 transarticular screw fixation by image- guided surgery. Spine 25: 2668–2674

    Article  PubMed  Google Scholar 

  102. White A, Panjabi MM (1990) Clinical biomechanics of the spine. Lippincott, Philadelphia

  103. Zeidman SM, Ducker TB (1994) Rheumatoid arthritis. Neuroanatomy, compression, and grading of deficits. Spine 19: 2259–2266

    PubMed  Google Scholar 

Download references

Interessenkonflikt:

Es besteht kein Interessenkonflikt. Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen. Die Präsentation des Themas ist unabhängig und die Darstellung der Inhalte produktneutral.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. E. Heyde.

Additional information

Herrn OMR Dr. med. D. Jungmichel, Chefarzt i. R., zum 75. Geburtstag gewidmet.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Heyde, C.E., Weber, U. & Kayser, R. Die rheumatisch bedingte Instabilität der oberen Halswirbelsäule. Orthopäde 35, 270–287 (2006). https://doi.org/10.1007/s00132-005-0918-2

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00132-005-0918-2

Schlüsselwörter

Keywords

Navigation