Zusammenfassung
Das vaskuläre Management bei anatomischen Leberresektionen ist entscheidend für die Erhaltung von ausreichend funktionellem Restlebervolumen. D. h. ein Leberlappen oder mehrere Lebersegmente brauchen einen suffizienten arteriellen und portal venösen Inflow und eine ausreichende venöse Drainage. Um dies zu erreichen, bedarf es einer ausgezeichneten präoperativen Bildgebung, entsprechende chirurgische Expertise mit Kenntnis der Anatomie, Physiologie, der Hämodynamik und ein bedachtes, vorsichtiges Vorgehen. Ebenso empfiehlt es sich, moderne Hilfsmittel der intraoperativen Diagnostik (i. e. intraoperative Sonographie mit Kontrastmittelverstärkung) und Parenchymdurchtrennung zu nutzen.
Abstract
The vascular management in anatomical liver resection plays a pivotal role in maintaining an adequately functional residual liver volume. In this respect it is essential to guarantee an adequate portal and arterial inflow as well venous outflow for the whole residual liver (lobe or segments). To achieve this, the liver surgeon should have excellent perioperative imaging, surgical expertise based on knowledge of vascular anatomy, physiology and hemodynamics of the liver and a well-designed and cautious operative strategy. The use of intraoperative ultrasonography (with or without contrast enhancement) and modern parenchymal dissectors (e.g. ultrasound or water jet dissectors) are strongly recommended.
Literatur
Abdel-Misih SR, Bloomston M (2010) Liver anatomy. Surg Clin North Am 90(4):643–653. doi:10.1016/j.suc.2010.04.017. S0039-6109(10)00052-6 [pii]
Azoulay D, Maggi U, Lim C et al (2014) Liver resection using total vascular exclusion of the liver preserving the caval flow, in situ hypothermic portal perfusion and temporary porta-caval shunt: a new technique for central tumors. Hepatobiliary Surg Nutr 3(3):149–153. doi:10.3978/j.issn.2304-3881.2014.05.02. hbsn-03-03-149 [pii]
Bismuth H (2013) Revisiting liver anatomy and terminology of hepatectomies. Ann Surg 257(3):383–386. doi:10.1097/SLA.0b013e31827f171f. 00000658-201303000-00002 [pii]
Bockhorn M, Benko T, Opitz B et al (2008) Impact of hepatic vein deprivation on liver regeneration and function after major hepatectomy. Langenbecks Arch Surg 393(4):527–533. doi:10.1007/s00423-007-0219-9
Couinaud C, Peres C (1957) Is resection of the last small intestinal loop a hazardous intervention? Is it necessary to set aside the benefit of right hemicolectomy? Reflections on 5 cases. J Chir (Paris) 73(5):461–469
Donadon M, Torzilli G (2013) Intraoperative ultrasound in patients with hepatocellular carcinoma: from daily practice to future trends. Liver Cancer 2(1):16–24. doi:10.1159/000346421. lic-0002-0016 [pii]
Eipel C, Abshagen K, Vollmar B (2012) Small-for-size: experimental findings for liver surgery. Chirurg 83(3):238–246. doi:10.1007/s00104-011-2179-4
Furchtgott LA, Chow CC, Periwal V (2009) A model of liver regeneration. Biophys J 96(10):3926–3935. doi:10.1016/j.bpj.2009.01.061. S0006-3495(09)00611-0 [pii]
Furrer K, Tian Y, Pfammatter T et al (2008) Selective portal vein embolization and ligation trigger different regenerative responses in the rat liver. Hepatology 47(5):1615–1623. doi:10.1002/hep.22164
Gurusamy KS, Sheth H, Kumar Y et al (2009) Methods of vascular occlusion for elective liver resections. Cochrane Database Syst Rev 1:CD007632. doi:10.1002/14651858.CD007632
Hashimoto T, Kokudo N, Orii R et al (2007) Intraoperative blood salvage during liver resection: a randomized controlled trial. Ann Surg 245(5):686–691. doi:10.1097/01.sla.0000255562.60215.3b
Hohenberger W, Ott R (2001) The anterior approach to hemihepatectomy. Chirurg 72(2):125–130
Katagiri S, Yamamoto M (2014) Multidisciplinary treatments for hepatocellular carcinoma with major portal vein tumor thrombus. Surg Today 44(2):219–226. doi:10.1007/s00595-013-0585-6
Koch M, Kienle P, Hinz U et al (2005) Detection of hematogenous tumor cell dissemination predicts tumor relapse in patients undergoing surgical resection of colorectal liver metastases. Ann Surg 241(2):199–205. doi:00000658-200502000-00001 [pii]
Kogure K, Ishizaki M, Nemoto M et al (2007) Close relation between the inferior vena cava ligament and the caudate lobe in the human liver. J Hepatobiliary Pancreat Surg 14(3):297–301. doi:10.1007/s00534-006-1148-7
Königsrainer I, Nadalin S, Königsrainer A (2010) Right hemihepatectomy by suprahilar intrahepatic transection of the right hemipedicle using a vascular stapler. J Vis Exp 35. doi:10.3791/1750. 1750 [pii]
Kruger T, Mustafi M, Nadalin S, Aebert H (2010) Vena cava sarcoma with tumor embolus in the pulmonary artery: surgical treatment. Ann Thorac Surg 90(2):642–644. doi:10.1016/j.athoracsur.2010.02.023
Ladurner R, Königsrainer A (2007) Liver surgery: what is feasible? Zentralbl Chir 132(4):274–280. doi:10.1055/s-2007-981233
Lang H (2007) Liver resection: part I. Anatomy and operative planning. Chirurg 78(8):761–773 (quiz 774). doi:10.1007/s00104-007-1392-7
Lang H, Radtke A, Hindennach M et al (2005) Impact of virtual tumor resection and computer-assisted risk analysis on operation planning and intraoperative strategy in major hepatic resection. Arch Surg 140(7):629–638 (discussion 638). doi:140/7/629 [pii]. 10.1001/archsurg.140.7.629
Majno P, Mentha G, Toso C et al (2014) Anatomy of the liver: an outline with three levels of complexity – a further step towards tailored territorial liver resections. J Hepatol 60(3):654–662. doi:10.1016/j.jhep.2013.10.026. S0168-8278(13)00752-6 [pii]
Miyaoka Y, Miyajima A (2013) To divide or not to divide: revisiting liver regeneration. Cell Div 8(1):8. doi:10.1186/1747-1028-8-8. 1747-1028-8-8 [pii]
Oldhafer KJ, Donati M, Lipp M et al (2012) Anterior approach liver resection with the liver hanging maneuver. Technique and indications. Chirurg 83(1):65–70. doi:10.1007/s00104-011-2169-6
Oldhafer KJ, Stavrou GA, Donati M et al (2013) Extracorporeal tumor cell filtration during extended liver surgery: first clinical use of leukocyte depletion filters – case series. World J Surg Oncol 11:159. doi:10.1186/1477-7819-11-159. 1477-7819-11-159 [pii]
Orimo T, Kamiyama T, Yokoo H et al (2014) Usefulness of artificial vascular graft for venous reconstruction in liver surgery. World J Surg Oncol 12:113. doi:10.1186/1477-7819-12-113. 1477-7819-12-113 [pii]
Otsubo T (2012) Control of the inflow and outflow system during liver resection. J Hepatobiliary Pancreat Sci 19(1):15–18. doi:10.1007/s00534-011-0451-0
Radtke A, Nadalin S, Sotiropoulos GC et al (2006) Parenchyma transection in adult live donor liver transplantation: the virtual dilemma of „where to cut“. Experience based on virtual 3-dimensional computed tomography imaging reconstructions. Hepatogastroenterology 53(72):811–815
Rau HG, Schauer R, Pickelmann S et al (2001) Dissection techniques in liver surgery. Chirurg 72(2):105–112
Richardson AJ, Laurence JM, Lam VW (2012) Portal triad clamping versus other methods of vascular control in liver resection: a systematic review and meta-analysis. HPB (Oxford) 14(6):355–364. doi:10.1111/j.1477-2574.2012.00466.x
Settmacher U, Thelen A, Jonas S et al (2005) Resection and reconstruction of the retrohepatic vena cava in combination with liver resections. Zentralbl Chir 130(2):104–108. doi:10.1055/s-2005-836389
Simillis C, Li T, Vaughan J et al (2014) Methods to decrease blood loss during liver resection: a network meta-analysis. Cochrane Database Syst Rev 4:CD010683. doi:10.1002/14651858.CD010683.pub2
Strasberg SM (2005) Nomenclature of hepatic anatomy and resections: a review of the Brisbane 2000 system. J Hepatobiliary Pancreat Surg 12(5):351–355. doi:10.1007/s00534-005-0999-7
Strasberg SM, Helton WS (2011) An analytical review of vasculobiliary injury in laparoscopic and open cholecystectomy. HPB (Oxford) 13(1):1–14. doi:10.1111/j.1477-2574.2010.00225.x
Takayama T, Makuuchi M, Kubota K et al (2001) Randomized comparison of ultrasonic vs clamp transection of the liver. Arch Surg 136(8):922–928. doi:soa0263 [pii]
Torzilli G, Makuuchi M (2003) Intraoperative ultrasonography in liver cancer. Surg Oncol Clin N Am 12(1):91–103
Yamamoto Y (2013) Ante-situm hepatic resection for tumors involving the confluence of hepatic veins and IVC. J Hepatobiliary Pancreat Sci 20(3):313–323. doi:10.1007/s00534-012-0525-7
Yokoyama S, Yokoyama Y, Kawai T et al (2006) Biphasic activation of liver regeneration-associated signals in an early stage after portal vein branch ligation. Biochem Biophys Res Commun 349(2):732–739. doi:S0006-291X(06)01897-3 [pii]. 10.1016/j.bbrc.2006.08.083
Einhaltung ethischer Richtlinien
Interessenkonflikt. S. Nadalin, I. Capobianco und A. Königsrainer geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nadalin, S., Capobianco, I. & Königsrainer, A. Vaskuläres Management bei anatomischen Leberresektionen. Chirurg 86, 121–124 (2015). https://doi.org/10.1007/s00104-014-2882-z
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00104-014-2882-z