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Antitumor triterpenes from medicinal plants

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Abstract

Thirteen kinds of naturally occurring or derivatised triterpenes, reported to have an antitumoral property, were reinvestigated on the basis of their direct cytotoxicity or the inhibitory activity on cell growth against five kinds of cultured human tumor cells,i. e., A-549, SK-OV-3, SK-MEL-2, XF498 and HCT15,in vitro. Ursonic acidIII, betulinic acidVIII, betulonic acidX and glycyrrhetinic acidXI were exhibited a marked inhibition on cell growth.

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Ryu, S.Y., Choi, S.U., Lee, S.H. et al. Antitumor triterpenes from medicinal plants. Arch. Pharm. Res. 17, 375–377 (1994). https://doi.org/10.1007/BF02974180

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