Abstract
Genetic variation in the Indian pygmy field miceMus booduga and theMus terricolor complex and in the house mouseMus musculus tytleri was analysed electro phoretically at 20 enzymatic and nonenzymatic protein loci. The results show an unusually high genetic variation in the field mice in terms of per cent polymorphism (P = 75 to 90 at 0-95 level), observed heterozygosity (Ho = 0.215[ ± 0.213] to 0.314 [±0.236]) and average number of alleles(A = 2.0[± 0.858] to 2.38 [±0.868]). Very high values of P,Ho andA were also observed for the house mouse. Genetic distance (D) determined by using Nei’s (1978) formula in theM. terricolor complex ranged from the lowest,D = 0.082, betweenM. terricolor I and II to the highest,D = 0.155, betweenM. terricolor II and III. Genetic distance betweenM. booduga and theM. terricolor complex was 0-259 and that between the house mouseM. m. tytleri and theM. booduga-terricolor lineage was 0.285. TheseD values corroborate that the pygmy field and house mice are closely allied.
Similar content being viewed by others
References
Avise J. C, Smith M. H. and Selander R. K. 1979 Biochemical polymorphism and systematics in the genusPeromyscus. VII. Geographic differentiation in members of thetruei andmaniculatus species groups.J. Mammal. 60: 177–192
Bahadur M. and Sharma T. 1996 Rapid evolution of post-zygotic reproductive isolation in theMus terricolor complex in the light of mitochondrial DNA restriction profiles. Sixth All-India Conference on Cytology and Genetics, Rohtak, India. Abstracts, p. 1
Benado M., Aguilera M., Reig O. A. and Ayala F. J. 1979 Biochemical genetics of chromosomal forms of Venezuelan spiny rats of theProechimys guairae andProechimys trinitatus superspecies.Genetica 50: 89–97
Berry R. I. and Peters J. 1977 Heterogeneous heterozygosities inMus musculus populations.Proc. R. Soc. London B197: 485–503
Bonhomme F., Catalan J., Britton-Davidian J., Chapman V. M, Moriwaki K., Nevo E. and Thaler L. 1984 Biochemical diversity and evolution of genusMus.Biochem. Genet. 22: 275–303
Britton-Davidian J. 1990 Genie differentiation inM. m. domesticus populations from Europe, the Middle East and North Africa: Geographic patterns and colonization events.Biol. J. Linn. Soc. 41: 27–45
Britton-Davidian J., Nadeau J. H., Croset H. and Thaler L. 1989 Genie differentiation and origin of Robertsonian populations of the house mouse (Mus musculus domesticus Rutty).Genet. Res. 53: 29–44
Carraway L. N. and Kennedy P. K. 1993 Genetic variation inThomomys bulbivorus, an endemic to the Willamette Valley, Oregon.J. Mammal. 74: 952–962
Chatterjee B., Bahadur M. and Sharma T. 1994 Mitochondrial DNA restriction maps ofMus booduga, Mus terricolor andMus musculus tytleri.J. Genet. 73: 57–64
Cheong N. 1986 Evolutionary divergence in Indian pygmy mice: Cytogenetics, habitat and behaviour studies. Ph. D. thesis, Banaras Hindu University, Varanasi, India
Cohen B. L. 1960 Genetics of plasma transferrins in the mouse.Genet. Res. 1: 431–438
Din W., Anand R., Boursot P., Darviche D., Jouvin-Marche E., Dod B., Orth A., Talwar G. P., Cazenave P.-A. and Bonhomme F. 1996 Origin and radiation of the house mouse: Clues from nuclear genes.J. Evol. Biol. 9: 519–539
Ellerman J. R. 1961 InFauna of India—Vol. III. Pt. II Mammalia, Rodentia. (ed.) M. L. Roonwal (Delhi: Zoological Survey of India) pp. 483–873
Gillespie J. H. and Guess H. A. 1978 A general model to account for enzyme variation in natural populations.Genetics 76: 837–848
Haldane J. B. S. 1922 Sex ratio and unisexual sterility in hybrid animals. J.Genetics 12: 101–109
Harris H. and Hopkinson D. A. 1976Handbook of enzyme electrophoresis in human genetics (Amsterdam: North-Holland)
Hartl D. L. 1980Principles of population genetics (Sunderland, Mass., USA: Sinauer)
Hedrick P. W. 1986 Genetic polymorphism in heterogeneous environments: A decade later.Annu. Rev. Ecol. Syst. 17: 535–566
Johnson W. E. and Selander R. K. 1971 Protein variation and systematics in kangaroo rats (GenusDipodomys).Syst. Zool. 20: 377–405
Johnson W. E., Selander R. K., Smith M. H. and Kim Y. J. 1972 Biochemical genetics of sibling species of cotton rat (Sigmodon). Studies in Genetics VII, University of Texas (Austin) Publications 213: 297–305
Kilpatrick C. W. and Zimmerman E. G. 1976 Genetic variation and systematics of four species of thePeromyscus boylii species group.Syst. Zool. 24: 143–162
Lewontin R. C, Ginzburg L. R. and Tuljapurkar S. D. 1978 Heterosis as an explanation for large amount of genie polymorphism.Genetics 88: 149–169
Lowry O. H., Rosebrough N. J., Farr A. L. and Randall R. J. 1951 Protein measurement with the Folin Phenol Reagent.J. Biol. Chem. 193: 265–275
Markvong A., Marshall J. T., Pathak S. and Hsu T. C. 1975 Chromosomes and DNA ofMus: The karyotype ofMus flavidiventris andMus dunni. Cytogenet. Cell Genet. 14: 116–125
Matthey R. and Petter F. 1968 Existence de deux especes distinctes, l’une chromosomiquement polymorphe chezdesMus indiens du groupebooduga. Etude cytogenetique et taxonomique.Rev. Suisse Zool. 75: 461–498
Misonne X. 1969 African and Indo-Australian muridiae, evolutionary trends.Ann. Mus. R. Afr. Centr. Tervuren Zool. 172: 1–219
Morton J. R. 1966 The multiple electrophoretic bands of mouse hemoglobins.Genet. Res. 7: 76–85
Musser G. G. and Carleton M. D. 1993 Family Muridae. InMammal species of the world: A taxonomic and geographic reference, 2nd edition (eds.) D. E. Wilson and D. M. Reeder (Washington, DC: Smithsonian Institution), pp. 501–756
Navarro M. N. Y. and Britton-Davidian J. 1989 Genetic structure of insular Mediterranean populations of the house mouse.Biol. J. Linn. Soc. 36: 377–390
Nei M. 1978 Estimation of average heterozygosity and genetic distance from a small number of individuals.Genetics 89: 583–590
Nevo E. 1983 Population genetics and ecology: The interface. InEvolution from molecules to man (ed.) D. S.Bendall (Cambridge: Cambridge University Press) pp. 287–321
Nevo E. 1988 Genetic diversity in nature, Patterns and theory. InEvolutionary biology (eds.) M. K. Hecht and B. Wallace (New York: Plenum) vol. 23, pp. 217–246
Nevo E. and Shaw C. R. 1972 Genetic variation in a subterranean mammal,Spalax ehrenbergi. Biochem. Genet. 7: 235–241
Nevo E., Kim Y. J., Shaw C. R. and Thaler C. S. Jr 1974 Genetic variation, selection and speciation inThomomys talpoides, pocket gophers.Evolution 28: 1–23
Nevo E., Ben-Shlomo R., Beiles A., Jarvis J. U. M. and Hickman G. C. 1987 Allozyme differentiation and systematics of the endemic subterraean mole rats of South Africa.Biochem. Syst. Ecol. 15: 489–502
Patnaik R., Jaeger J.-J., Affray J.-C. and Sahni A. 1996 House mouse ancestor from late Pliocene Siwalik sediments of India.C. R. Acad. Set, Paris 319: 431–434
Patton J. L. and Yang S. Y. 1977 Genetic variation inThomomys bottae pocket gophers: Macrogeographic patterns.Evolution 31: 697–720
Pemberton J. M., Albon S. D., Guinness F. E., Clutton-Brock T. H. and Berry R. J. 1988 Genetic variation and juvenile survival in red deer.Evolution 42: 921–934
Peters J. and Nash H. R. 1978 Esterases ofMus musculus: substrate and inhibition characteristics, new isozymes and homologies with man.Biochem. Genet. 16: 553–569
Petras M. L. and Biddle F. G. 1967 Serum esterases in the house mouse,Mus musculus. Can. J. Genet. Cytol. 9: 704–710
Sage R. D. 1981 Wild mice. InThe mouse in biomedical research (eds.) L. Foster, D. Small and G. Fox (New York: Academic Press) vol. 4, pp. 39–90
Said K. and Britton-Davidian J. 1991 Genetic differentiation and habitat partition of Robertsonian house mouse populations(Mus musculus domesticus) of Tunisia.J. Evol. Biol. 3: 409–427
Selander R. K. and Yang S. Y. 1969 Protein polymorphism and genie heterozygosity in a wild population of the house mouse (Mus musculus).Genetics 63: 653–667
Selander R. K., Smith M. H., Yang S. Y., Johnson W. E. and Centry J. B. 1971 Biochemical polymorphism and systematics in the genusPeromyscus. I. Variation in the old field mouse (Peromyscus polionotus). Studies in Genetics, VI, University of Texas (Austin) Publications 7103: 49–90
Sen S. and Sharma T. 1983 Role of constitutive heterochromatin in evolutionary divergence: Results of chromosome banding and condensation inhibition studies inMus musculus, Mus booduga andMus dunni. Evolution 37: 628–636
Sharma T. and Garg G. S. 1975 Constitutive heterochromatin and karyotype variation in Indian pygmy mouse,Mus dunni. Genet. Res. 25: 189–191
Sharma T., Cheong N., Sen P. and Sen S. 1986 Constitutive heterochromatin and evolutionary divergence ofMus dunni, Mus booduga andMus musculus. Curr. Top. Microbiol. Immunol. 127: 35–44
Singh S. and Sharma T. 1996 Biochemical genetics of Indian pygmy field mice: Superoxide dismutase (Sod-1) as diagnostic marker inMus booduga.Biochem. Genet. 34: 437–441
Teska W. R., Smith M. H. and Novak J. M. 1990 Food quality, heterozygosity and fitness correlates inPeromyscus polionotus.Evolution 44: 1318–1325
ValdiyaK. S. 1993 Uplift and geomorphic rejuvenation of the Himalaya in the Quaternary period.Curr. Sci. 64: 873–885
Wadia D. N. 1966Geology of India, 3rd edition (revised) (London: Macmillan)
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Singh, S., Sharma, T. High levels of genetic variation in Indian field and house mice. J. Genet. 76, 189–200 (1997). https://doi.org/10.1007/BF02932217
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02932217