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Essential trace metals and specific organ weights in diet-restricted and ad lib-fed rats

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Abstract

Manganese, copper, iron, zinc, and specific organ weights (relative to body weight) of the heart, liver, and kidney were compared between a 65% diet-restricted group and an ad lib-fed control group of young male Sprague-Dawley rats. Elevated concentrations of Cu (12%) in the liver, and of Mn (12–26%) and Fe (17–69%) in all three organs, occurred in the diet-restricted group. Specific heart weight was unchanged despite the 40% difference in group body weights. Specific liver weight decreased 13% and specific kidney weight increased 13%.

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Authors and Affiliations

  1. Department of Environmental Health, University of Cincinnati College of Medicine, 3223 Eden Ave., 45267-0056, Cincinnati, OH

    Brian C. Lee, Klaus L. Stemmer & Harold G. Petering

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  1. Brian C. Lee
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  2. Klaus L. Stemmer
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  3. Harold G. Petering
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Lee, B.C., Stemmer, K.L. & Petering, H.G. Essential trace metals and specific organ weights in diet-restricted and ad lib-fed rats. Biol Trace Elem Res 8, 1–9 (1985). https://doi.org/10.1007/BF02917598

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  • DOI: https://doi.org/10.1007/BF02917598

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