Abstract
The culture medium composition for cellulolytic bacteria growing on sugar cane wastes was optimized. A modified method of Rosenbrock was employed for shaker culture medium and a factorial plan design for fermentor culture medium optimization. A much more economical and productive medium was obtained for the production of single cell protein (SCP). A biomass concentration of 4.3 g/L was obtained in the optimized medium in batch fermentation, in comparison with 2.8 g/L previously obtained in the traditional medium under similar conditions.
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Rodriguez, H., Enriquez, A. & Volfová, O. Optimization of culture medium composition for cellulolytic bacteria by mathematical methods. Folia Microbiol 28, 163–171 (1983). https://doi.org/10.1007/BF02884079
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DOI: https://doi.org/10.1007/BF02884079