Summary
The mean bursting membrane tension, elastic area compressibility modulus, and cell diameter of PQX1/2 murine hybridomas, NS1 myelomas and SF9 insect cells were measured during batch cultures. The fragilities of the cells were characterised by these mechanical properties. In general, the bursting membrane tension and elastic area compressibility modulus rose during rapid growth phase and fell during the death phase. Among the three cell lines, NS1 myelomas seemed to be weakest, but all were weaker than TB/C3 murine hybridomas studied previously.
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Zhang, Z., Al-Rubeai & Thomas, C.R. Comparison of the fragilities of several animal cell lines. Biotechnol Tech 7, 177–182 (1993). https://doi.org/10.1007/BF02566144
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DOI: https://doi.org/10.1007/BF02566144