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Follow-up in colorectal cancer patients: A cost-benefit analysis

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Abstract

Background: No conclusive evidence exists concerning the effectiveness of follow-up programs after curative surgery for colorectal cancer, and presently cost-benefit analyses have not indicated that follow-up strategies increase survival or quality of life.

Methods: Five hundred five patients who survived curvative surgery for stage I–III colorectal adenocarcinoma were closely followed for at least 4 years.

Results: One hundred forty-one (28%) patients had recurrence. Of these, 32 underwent one or more surgical procedures for cure, whereas 109 could only benefit from palliation. Eighteen were cured. The mean survival of all recurrent cases was 44.4 months. Of those operated on with curative intent, the mean survival was 69.3 months compared with 37.1 months in those operated on with palliative intent. Of those 18 patients who were cured by reoperative surgery, the average survival was 81.4 months. The overall follow-up cost was $1,914,900 (U.S.) for the 505 patients; $13,580 (U.S.) for each recurrence, $59,841 (U.S.) for each case treated for cure, and $136,779 (U.S.) for those effectively cured.

Conclusions: Careful postoperative monitoring is expensive yet effective when one considers that one-quarter of the detected recurrences were suitable for potentially curative second surgery; however, only 3.6% of the original group were effectively cured. Follow-up programs should be tailored according to the stage and site of the primary to reduce costs.

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Authors and Affiliations

  1. From the Istituto di Chirurgia d'Urgenza, Università di Milano, Milan, Italy

    Paolo Setti-Carraro MD, Marco Segala MD & Giorgio Tiberio MD

  2. General Surgery 2, EIO-European Institute of Oncology, Milan, Italy

    Riccardo A. Audisio MD, Deborah Capko MD & Bruno Andreoni MD

Authors
  1. Riccardo A. Audisio MD
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  2. Paolo Setti-Carraro MD
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  3. Marco Segala MD
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  4. Deborah Capko MD
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  5. Bruno Andreoni MD
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  6. Giorgio Tiberio MD
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Audisio, R.A., Setti-Carraro, P., Segala, M. et al. Follow-up in colorectal cancer patients: A cost-benefit analysis. Annals of Surgical Oncology 3, 349–357 (1996). https://doi.org/10.1007/BF02305664

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  • DOI: https://doi.org/10.1007/BF02305664

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