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Some notes on differential chromosome activity inDrosophila

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Abstract

In the lethal mutantltl ofDrosophila melanogaster, a characteristic pattern of puffs on the right arm of the third chromosome is described. This pattern includes anaerobiosis puffs in some of the lethal larvae. Puffing, and incorporation of radioactive uridine was observed even at advanced stages of disintegration. From the behaviour of the chromosomes it may be concluded that the internal milieu ofltl larvae differs from that of artificially (by ligating) over-aged wild type larvae as well as from that of the imago.

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References

  • Ashburner, M. (1967). Patterns of puffing activity in the salivary gland chromosomes ofDrosophila. I. Autosomal puffing patterns in a laboratory stock ofDrosophila melanogaster.Chromosoma (Berl.)21 398–428.

    Google Scholar 

  • Baudisch, W. &R. Panitz (1968). Kontrolle eines biochemisches Merkmals in den Speicheldrüsen vonAcricotopus lucidus durch einen Balbianiring.Exp. Cell Res. 49:470–476.

    PubMed  Google Scholar 

  • Becker, H. J. (1959). Die Puffs der Speicheldrüsenchromosomen vonDrosophila melanogaster. I. Mitt. Beobachtungen zum Verhalten des Puffmusters im Normalstamm und bei zwei Mutanten,gian undlethal-giant larvae.Chromosoma (Berl.) 10:645–678.

    Google Scholar 

  • Becker, H. J. (1962). II. Mitt. Die Auslösung der Puffbildung, ihre Spezifität und ihre Beziehung zur Funktion der Ringdrüse.Chromosoma (Berl.) 13:341–384.

    Google Scholar 

  • Beermann, W. (1952). Chromomerenkonstanz und spezifische Modifikationen der Chromosomenstruktur in der Entwicklung und Organdifferenzierung vonChironomus tentans.Chromosoma (Berl.) 5:139–198.

    Google Scholar 

  • Beermann, W. (1961). Ein Balbianiring als locus einer Speicheldrüsenmutation.Chromosoma (Berl.) 12:1–25.

    Google Scholar 

  • Berendes, H. D. (1963). The salivary gland chromosomes ofDrosophila hydei Sturtevant.Chromosoma (Berl.) 14: 195–206.

    Google Scholar 

  • Berendes, H. D. (1965). Salivary gland function and chromosomal puffing patterns inDrosophila hydei.Chromosoma (Berl.).17: 35–77.

    Google Scholar 

  • Berendes, H. D. (1967). The hormone ecdysone as effector of specific changes in the pattern of gene activities ofDrosophila hydei.Chromosoma (Berl.) 22: 274–293.

    Google Scholar 

  • Berendes, H. D., F. M. A. van Breugel &Th. K. H. Holt (1965). Experimental puffs inDrosophila hydei salivary gland chromosomes.Chromosoma (Berl.) 16: 35–47.

    Google Scholar 

  • Berendes, H. D. &Th. K. H. Holt (1965). Differentiation of transplanted larval salivary glands ofDrosophila hydei in adults of the same species.J. Exp. Zool. 160: 299–317.

    PubMed  Google Scholar 

  • Bodenstein, D. (1943). Factors influencing growth and metamorphosis of the salivary gland inDrosophila.Biol. Bull. 84: 13–33.

    Google Scholar 

  • Breuer, M. &C. Pavan (1955). Behavior of polytene chromosomes ofRhynchosciara angelae at different stages of larval development.Chromosoma Berl. 7: 371–386.

    Google Scholar 

  • Breugel, F. M. A. van (1966). Puff induction in larval salivary gland chromosomes ofDrosophila hydei Sturtevant.Genetica 37: 17–28.

    PubMed  Google Scholar 

  • Breugel, F. M. A. van, A. Ray &H. Gloor (1968). A comparison of banding patterns in salivary gland chromosomes of two species ofDrosophila.Genetica 39: 165–192.

    PubMed  Google Scholar 

  • Bridges, C. B. (1935). Salivary chromosome maps with a key to the banding of the chromosomes ofDrosophila melanogaster.J. Heredity 26: 60–64.

    Google Scholar 

  • Brito da Cunha, A., J. S. Morgante, C. Pavan &M. C. Garrido (1968). Studies on cytology and differentiation inSciaridae. I. Chromosome changes induced by a Gregarine inTrichosia sp. (Diptera, Sciaridae).Carylogia 21: 271–282.

    Google Scholar 

  • Burdette, W. J. &R. Anderson (1965). Conditioned response of chromosomes ofDrosophila melanogaster to ecdysones.Genetics 51: 625–633.

    PubMed  Google Scholar 

  • Chen, P. S. (1951). A comparative study of the oxygen consumption in the three lethal mutants “ltr”, “lgl” and “lme” ofDrosophila melanogaster.Z. Indukt. Abstamm. u. Vererb. Lehre 84: 38–70.

    Google Scholar 

  • Clever, U. &P. Karlson (1960). Induktion von Puff-Veränderungen vonChironomus tentans durch Ecdyson.Exp. Cell Res. 20: 623–626.

    PubMed  Google Scholar 

  • Clever, U. (1961). Genaktivitäten in den Riesenchromosomen vonChironomus tentans und ihre Beziehungen zur Entwicklung. Mitt. I. Genaktivierungen durch Ecdyson.Chromosoma (Berl.) 12: 607–675.

    Google Scholar 

  • Clever, U. (1963). Von der Ecdysonkonzentration abhängige Genaktivitätsmuster in den Speicheldrüsenchromosomen vonChironomus tentans.Devel. Biol. 6: 73–98.

    Google Scholar 

  • Clever, U. (1966). Induction and repression of a puff inChironomus tentans.Devel. Biol. 14: 421–438.

    Google Scholar 

  • Desai, L. &R. Tencer (1968). Effects of histones and polylysine on the synthetic activity of the giant chromosomes of salivary glands of Dipteran larvae.Exp. Cell Res. 52: 185–197.

    PubMed  Google Scholar 

  • Diaz, M. &C. Pavan (1965). Changes in chromosomes induced by microorganism infection.P. N. A. S. (U. S. A.) 54: 1321–1327.

    Google Scholar 

  • Fedoroff, N. &R. Milkman (1964). Specific puff induction by tryptophan inDrosophila salivary chromosomes.Biol. Bull. 127: 369.

    Google Scholar 

  • Garcia-Bellido, A. (1965). Larvalentwicklung transplantierter Organe vonDrosophila melanogaster im Adultmilieu.J. Insect Physiol. 11: 1071–1078.

    Google Scholar 

  • Hadorn, E. &J. V. Neel (1938). Der hormonale Einfluss der Ringdrüse (corpus allatum) auf die Pupariumbildung bei Fliegen.Roux' Arch. 138: 281–304.

    Google Scholar 

  • Hadorn, E., W. Gehring &M. Staub (1963). Extensives Grössenwachstum larvaler Speicheldrüsenchromosomen vonDrosophila melanogaster im Adultmilieu.Experientia 19: 530–531.

    PubMed  Google Scholar 

  • Keyl, H. G. (1960). Erhöhung der chromosomalen Replikationsrate durch Mikrosporidieninfektion in Speicheldrüsenzellen vonChironomus.Naturwissenschaften 47: 212–213.

    Google Scholar 

  • Kobel, H. R. &F. M. A. van Breugel (1968). Observations onltl (lethal tumorous larvae) ofDrosophila melanogaster.Genetica 38: 305–327.

    PubMed  Google Scholar 

  • Kroeger, H. (1960). The induction of a new puffing pattern by transplantation of a new puffing pattern by transplantation of salivary gland nuclei into egg cytoplasm ofDrosophila.Chromosoma (Berl.) 11: 129–145.

    Google Scholar 

  • Kroeger, H. (1964). Zellphysiologische Mechanismen bei den Regulation von Genaktivitäten in den Riesenchromosomen vonChironomus thummi.Chromosoma (Berl.) 15: 36–70.

    Google Scholar 

  • Mechelke, F. (1953). Reversible Strukturmodifikationen der Speicheldrüsenchromosomen vonAcricotopus lucidus.Chromosoma (Berl.) 5: 511–543.

    Google Scholar 

  • Pavan, C. &R. Basile (1966). Chromosome changes induced bij infections in tissues of Rhynchosciara angelae. Science151: 1556–1558.

    Google Scholar 

  • Petersen, G. V. &E. J. Gardner (1965). Development of melanotic tumors in association with failure of pupation inDrosophila melanogaster.Genetics 52: 465. (Abstract).

    Google Scholar 

  • Ritossa, F. M. (1962). A new puffing pattern induced by temperature shock and DNP inDrosophila.Experientia 18: 571–572.

    Google Scholar 

  • Ritossa, F. M. (1963). New puffs induced by temperature shock, DNP and salicilate in salivary gland chromosomes ofD.melanogaster. D.I.S. 37: 122–123.

    Google Scholar 

  • Ritossa, F. M. (1964). Experimental activation of specific loci in polytene chromosomes ofDrosophila.Exp. Cell Res. 35: 601–607.

    PubMed  Google Scholar 

  • Ritossa, F. M. &R. C. von Borstel (1964). Chromosome puffs inDrosophila induced by ribonuclease.Science 145: 513–514.

    PubMed  Google Scholar 

  • Ritossa, F. M., J. F. Pulitzer, H. Swift &R. C. von Borstel (1965). On the action of ribonuclease on salivary gland cells ofDrosophila.Chromosoma (Berl.) 16: 144–151.

    Google Scholar 

  • Roberts, P., A. Kimball &C. Pavan (1967). Response ofRhynchosciara chromosomes to microsporidian infection. Increased polyteny and generalized puffing.Genetics 54: 357 (abstracts).

    Google Scholar 

  • Rodman, T. C. (1964). The larval characteristics and salivary gland chromosomes of a tumorigenic strain ofDrosophila melanogaster.J. Morph. 115: 419–446.

    PubMed  Google Scholar 

  • Rodman, T. C. (1965). Feulgen photometry of polytene nuclei. 5th. Ann. Meeting Am. Soc. Cell. Biol. (Abstracts). 87A.

  • Rodman, T. C. (1967). D.N.A. replication in salivary gland nuclei ofDrosophila melanogaster at successive larval and prepupal stages.Genetics 55: 375–386.

    PubMed  Google Scholar 

  • Rodman, T. C. (1968). Developmental stage and initiation of replication in polytene nuclei.Chromosoma (Berl.) 23: 271–287.

    Google Scholar 

  • Shaaya, E. &P. Karlson (1965). Der Ecdysontiter während der Insektenentwicklung. II. Die postembryonale Entwicklung der SchmeissfliegeCalliphora erythrocephala Meig.J. Ins. Physiol. 11: 65–69.

    Google Scholar 

  • Slizynski, B. M. (1964). Functional changes in polytene chromosomes ofDrosophila melanogaster. Cytologia29: 230–236.

    Google Scholar 

  • Staal, G. B. (1967). Plants as a source of insect hormones.Proc. Kon. Ned. Akad. Wetensch. (Amsterdam) Series C,70: 409–418

    Google Scholar 

  • Staub, M. (1969). Veränderungen im Puffmuster und das Wachstum der Riesenchromosomen in Speicheldrüsen vonDrosophila melanogaster aus spätlarvalen und embryonalen Spendern nack Kultur in vivo.Chromosoma (Berl.) 26: 76–104.

    Google Scholar 

  • Thomsen, E. (1952). Functional significance of the neuro-secretory brain cells and the corpus cardiacum in the female blow-fly,Calliphora erythrocephala Meig.J. Exp. Biol. 29: 137–172.

    Google Scholar 

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Authors and Affiliations

  1. Genetisch Laboratorium, Rijksuniversiteit Leiden, The Netherlands

    F. M. A. van Breugel & H. J. Bos

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  1. F. M. A. van Breugel
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  2. H. J. Bos
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van Breugel, F.M.A., Bos, H.J. Some notes on differential chromosome activity inDrosophila . Genetica 40, 359–378 (1969). https://doi.org/10.1007/BF01787362

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  • DOI: https://doi.org/10.1007/BF01787362

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