Summary
Octanoylglucose was synthesized from insoluble glucose and octanoic acid in acetonitrile, using lipase fromCandida antarctica as catalyst. The initial concentration of octanoic acid was optimized to give complete conversion of glucose to monoester and avoid diester formation. The acylation occurred exclusively at the primary hydroxyl group on the glucose ring.
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Ljunger, G., Adlercreutz, P. & Mattiasson, B. Lipase catalyzed acylation of glucose. Biotechnol Lett 16, 1167–1172 (1994). https://doi.org/10.1007/BF01020845
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DOI: https://doi.org/10.1007/BF01020845