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Intracytoplasmic hyaline inclusion bodies in the nerve cells of the hypoglossal nucleus in human autopsy material

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Summary

Intracytoplasmic hyaline inclusion bodies were found in the nerve cells of the hypoglossal nucleus in 150 cases out of 518 consecutive autopsy cases. These inclusion bodies are histomorphologically, histochemically and topographically distinct from any others previously described. Their incidence was found to increase with age. A high incidence among young patients with chronic alcoholism was also observed.

Zusammenfassung

Intracytoplasmische hyaline Einschlußkörperchen wurden in Nervenzellen des Nucleus hypoglossus in 150 von 518 laufenden Sektionsfällen gefunden. Diese Einschlußkörperchen lassen sich histomorphologisch, histochemisch und topographisch von allen früher beschriebenen unterscheiden. Sie traten vermehrt mit steigendem Alter auf und werden auch vermehrt bei jungen Patienten mit chronischem Alkoholismus beobachtet.

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Author notes

  1. Yoshio Takei

    Present address: Department of Pathology (Neuropathology), Yale University School of Medicine, New Haven, Conn

  2. Suzanne Samuels Mirra

    Present address: Department of Neuropathology, Montefiore Hospital and Medical Center, Bronx, N.Y.

Authors and Affiliations

  1. Neuropathology Laboratory, Institute of Pathology, State University-Kings County Hospital Center, Brooklyn, New York

    Yoshio Takei & Suzanne Samuels Mirra

Authors
  1. Yoshio Takei
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  2. Suzanne Samuels Mirra
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Takei, Y., Mirra, S.S. Intracytoplasmic hyaline inclusion bodies in the nerve cells of the hypoglossal nucleus in human autopsy material. Acta Neuropathol 17, 14–23 (1971). https://doi.org/10.1007/BF00684737

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  • DOI: https://doi.org/10.1007/BF00684737

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