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A comparative study in young male animals of 10 species of the distribution of alkaline phosphatase activity in small arteries

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Summary

The distribution of alkaline phosphatase activity in the walls of small arteries measuring 100–200 μ in internal diameter in the collapsed state was investigated in nine organs in male animals of each of ten species employing the Gomori and azo-coupling techniques. Alkaline phosphatase activity was high in relation to the arterial endothelium of the chick, hen, turkey, rabbit, frog and man but was related to the arterial adventitia and not to the endothelium in the rat. In the guinea pig and hamster arterial alkaline phosphatase activity was uniformly low or absent. Within nine of these ten species the pattern of organ distribution of arterial alkaline phosphatase activity in vessels of comparable size was uniform. In the cat however, enzyme activity was confined to the adventitia of small cerebral arteries and to the media of the smallest arteries (arterioles) in all organs except the testis from which arterial activity was absent.

The distribution of alkaline phosphatase activity in 100–200 μ, arteries in the species investigated was not directly related to the presence of capillary endothelial activity which was detected in all the organs examined. The activity in the walls of the smallest arteries (arterioles) was located in different sites in different species.

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Authors and Affiliations

  1. Division of Experimental Pathology, Kennedy Institute, London, UK

    Mohamed Aref H. A. El-Maghraby & Dugald Lindsay Gardner

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  1. Mohamed Aref H. A. El-Maghraby
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  2. Dugald Lindsay Gardner
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United Arab Republic Research Fellow.

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El-Maghraby, M.A.H.A., Gardner, D.L. A comparative study in young male animals of 10 species of the distribution of alkaline phosphatase activity in small arteries. Histochemie 16, 227–235 (1968). https://doi.org/10.1007/BF00307851

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  • DOI: https://doi.org/10.1007/BF00307851

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