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Neuroanatomical study of afferent projections to the supramammillary nucleus of the rat

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Abstract

We examined the regions projecting to the supramammillary nucleus of the rat with retrograde transport of WGA-HRP and WGA, and anterograde transport of Phaseolus vulgaris leucoagglutinin. The supramammillary nucleus receives major descending afferents from the infralimbic cortex, the dorsal peduncular cortex, the nucleus of the diagonal band of Broca, the medial and lateral preoptic nuclei, bilaterally. The major ascending afferents come from the pars compacta of the nucleus centralis superior, the ventral tegmental nucleus, and the laterodorsal tegmental nucleus. The supramammillary nucleus also receives a few (but distinct) fibers from the anterior and lateral hypothalamic nuclei, the ventral premammillary nucleus, the interpeduncular nucleus, the cuneiform nucleus, the dorsal raphe nucleus, the incertus nucleus, and the C3 region including the prepositus hypoglossi nucleus. All descending fibers run through the medial forebrain bundle. Almost all ascending fibers from the pars compacta of the nucleus centralis superior and the laterodorsal tegmental nucleus run through the mammillary peduncle, and terminate throughout the supramammillary nucleus. A few fibers from the laterodorsal tegmental nucleus and the C3 region run through the fasciculus longitudinalis dorsalis and terminate in the dorsal part of the supramammillary nucleus including the supramammillary decussation.

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Abbreviations

a:

anterior commissure

AC:

accumbens nucleus

AR:

arcuate nucleus

BS:

bed nucleus of the stria terminalis

C3:

C3 adrenergic region

CA:

interstitial nucleus of Cajal

CC:

pars compacta of the nucleus centralis superior

CS:

nucleus centralis superior

CU:

cuneiform nucleus

CX:

cingulate cortex

DB:

nucleus of the diagonal band of Broca

DH:

dorsomedial hypothalamic nucleus

ds:

decussation of the superior cerebellar peduncle

DX:

dorsal peduncular cortex

f:

fornix

fld:

fasciculus longitudinalis dorsalis

flm:

fasciculus longitudinalis medialis

IN:

incertus nucleus

IX:

infralimbic cortex

LC:

nucleus of the locus ceruleus

le:

lemniscus medialis

LH:

lateral hypothalamic nucleus

LM:

lateral mammillary nucleus

LO:

lateral preoptic nucleus

LS:

lateral septal nucleus

LT:

laterodorsal tegmental nucleus

mfb:

medial forebrain bundle

MM:

medial mammillary nucleus

MO:

medial preoptic nucleus

mp:

mammillary peduncle

mt:

mammillothalamic tract

MV:

medial vestibular nucleus

PD:

dorsal premammillary nucleus

PH:

prepositus hypoglossi nucleus

PV:

ventral premammillary nucleus

RD:

dorsal raphe nucleus

rf:

fasciculus retroflexus

SUM:

supramammillary nucleus

sx:

supramammillary decussation

T:

tenia tecta

TD:

dorsal tegmental nucleus

TM:

tuberomammillary nucleus

TV:

ventral tegmental nucleus

VT:

ventral tegmental area of Tsai

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Authors and Affiliations

  1. Department of Anatomy, Hyogo College of Medicine, Mukogawa-cho, Nishinomiya, 663, Hyogo, Japan

    Tetsu Hayakawa, Hisao Ito & Katuya Zyo

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  1. Tetsu Hayakawa
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  2. Hisao Ito
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  3. Katuya Zyo
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Hayakawa, T., Ito, H. & Zyo, K. Neuroanatomical study of afferent projections to the supramammillary nucleus of the rat. Anat Embryol 188, 139–148 (1993). https://doi.org/10.1007/BF00186247

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  • DOI: https://doi.org/10.1007/BF00186247

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