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Nucleus Tractus Solitarius

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Neuroanatomy and Neurophysiology of the Larynx

Abstract

The nucleus tractus solitarius (NTS) is subdivided into nine subnuclei based on their cellular morphology. The NTS receives afferent input from the vagus, glossopharyngeal, and facial nerves. The NTS neurons mainly project to the medulla oblongata, pons, and thalamus and are involved in the regulation of respiration, heart and blood vessels, taste, and neurohypophysial hormone secretion. A variety of neurotransmitters have been identified in the somata and axons of the NTS neurons. Sensory nerve fibers in the larynx project through the internal branch of the superior laryngeal nerve to the interstitial subnucleus on the central side, and their somata are located in the nodose ganglion. We showed that sensory nerve fibers in the rat inferior laryngeal nerve project to the interstitial subnucleus, using wheat germ agglutinin-horseradish peroxidase (WGA-HRP) as a transganglionic tracer.

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References

  1. Törk I, McRitchie DA, Rikard-Bell GC, Paxinos G. Autonomic regulatory centers in the medulla oblongata. In: Paxinos G, editor. The human nervous system. New York: Academic; 1990. p. 221–59.

    Chapter  Google Scholar 

  2. Sano Y. Shinkei-Kagaku (Keitaigakuteki Kiso) Vol. 2. Spinal cord and brainstem. Kyoto: Kinpodo; 1999. p. 394–422.

    Google Scholar 

  3. Van der Gugten J, Palkovits M, Wijnen HL, Versteeg DH. Regional distribution of adrenaline in rat brain. Brain Res. 1976;107:171–5.

    Article  PubMed  Google Scholar 

  4. Versteeg DH, Van Der Gugten J, De Jong W, Palkovits M. Regional concentrations of noradrenaline and dopamine in rat brain. Brain Res. 1976;113:563–74.

    Article  CAS  PubMed  Google Scholar 

  5. Armstrong DM, Ross CA, Pickel VM, Joh TH, Reis DJ. Distribution of dopamine-, noradrenaline-, and adrenaline-containing cell bodies in the rat medulla oblongata: demonstrated by the immunocytochemical localization of catecholamine biosynthetic enzymes. J Comp Neurol. 1982;212:173–87.

    Article  CAS  PubMed  Google Scholar 

  6. Kalia M, Fuxe K. Rat medulla oblongata. I. Cytoarchitectonic considerations. J Comp Neurol. 1985;233:285–307.

    Article  CAS  PubMed  Google Scholar 

  7. Lambas-Senas L, Chamba G, Dennis T, Renaud B, Scatton B. Distribution of dopamine, noradrenaline and adrenaline in coronal sections of the rat lower brainstem. Brain Res. 1985;347:306–12.

    Article  CAS  PubMed  Google Scholar 

  8. Maley BE, Newton BW, Howes KA, Herman LM, Oloff CM, Smith KC, Elde RP. Immunohistochemical localization of substance P and enkephalin in the nucleus tractus solitarii of the rhesus monkey, Macaca mulatta. J Comp Neurol. 1987;260:483–90.

    Article  CAS  PubMed  Google Scholar 

  9. Yamazoe M, Shiosaka S, Shibasaki T, Ling N, Tateishi K, Hashimura E, Hamaoka T, Kimmel JR, Matsuo H, Tohyama M. Distribution of six neuropeptides in the nucleus tractus solitarii of the rat: an immunohistochemical analysis. Neuroscience. 1984;13:1243–66.

    Article  CAS  PubMed  Google Scholar 

  10. Berk ML, Smith SE, Karten HJ. Nucleus of the solitary tract and dorsal motor nucleus of the vagus nerve of the pigeon: localization of peptide and 5-hydroxytryptamine immunoreactive fibers. J Comp Neurol. 1993;338:521–48.

    Article  CAS  PubMed  Google Scholar 

  11. Kalia M, Fuxe K, Hökfelt T, Johansson O, Lang R, Ganten D, Cuello C, Terenius L. Distribution of neuropeptide immunoreactive nerve terminals within the subnuclei of the nucleus of the tractus solitarius of the rat. J Comp Neurol. 1984;222:409–44.

    Article  CAS  PubMed  Google Scholar 

  12. Lee HS, Basbaum AI. Immunoreactive pro-enkephalin and prodynorphin products are differentially distributed within the nucleus of the solitary tract of the rat. J Comp Neurol. 1984;230:614–9.

    Article  CAS  PubMed  Google Scholar 

  13. Hassen AH, Feuerstein GZ, Faden AI. Cardiovascular responses to opioid agonists injected into the nucleus of tractus solitarius of anesthetized cats. Life Sci. 1982;31:2193–6.

    Article  CAS  PubMed  Google Scholar 

  14. Sweazey RD, Bradley RM. Central connections of the lingual-tonsillar branch of the glossopharyngeal nerve and the superior laryngeal nerve in lamb. J Comp Neurol. 1986;245:471–82.

    Article  CAS  PubMed  Google Scholar 

  15. Nomura S, Mizuno N. Central distribution of afferent and efferent components of the glossopharyngeal nerve: an HRP study in the cat. Brain Res. 1982;236:1–13.

    Article  CAS  PubMed  Google Scholar 

  16. Hisa Y, Lyon MJ, Malmgren LT. Central projection of the sensory component of the rat recurrent laryngeal nerve. Neurosci Lett. 1985;55:185–90.

    Article  CAS  PubMed  Google Scholar 

  17. Hanamori T, Smith DV. Central projections of the hamster superior laryngeal nerve. Brain Res Bull. 1986;16:271–9.

    Article  CAS  PubMed  Google Scholar 

  18. Ootani S, Umezaki T, Shin T, Murata Y. Convergence of afferents from the SLN and GPN in cat medullary swallowing neurons. Brain Res Bull. 1995;37:397–404.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Yasuo Hisa .

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Mukudai, S., Sugiyama, Y., Hisa, Y. (2016). Nucleus Tractus Solitarius. In: Hisa, Y. (eds) Neuroanatomy and Neurophysiology of the Larynx. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55750-0_11

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  • DOI: https://doi.org/10.1007/978-4-431-55750-0_11

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