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Fourier transform Raman spectroscopic studies of human bone

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We have concluded preliminary investigations concerning the composition of human cortical bone tissue, and of a number of samples of synthetic hydroxyapatite, using Fourier transform Raman (FT-Raman) spectroscopy. Deproteination procedures to remove the bulk of the collagen present in the tissue have allowed isolation of the mineral phase, and a comparison of the spectra obtained from the latter with those of synthetic hydroxyapatites has highlighted a number of discrepancies. FT-Raman spectra obtained for whole, wet bone samples have produced a degree of spectral detail that is much improved upon that available from existing studies. This has mainly been achieved by the successful elimination of fluorescence from the tissue, a problem which has dogged the Raman analysis of bone in particular.

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Authors and Affiliations

  1. Interdisciplinary Research Centre in Biomedical Materials, Queen Mary & Westfield College, University of London, Mile End Road, E1 4NS, London, UK

    R. Smith & I. Rehman

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  1. R. Smith
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  2. I. Rehman
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Smith, R., Rehman, I. Fourier transform Raman spectroscopic studies of human bone. J Mater Sci: Mater Med 5, 775–778 (1994). https://doi.org/10.1007/BF00120375

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  • DOI: https://doi.org/10.1007/BF00120375

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