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Hemmung und Induktion des Arzneimittelstoffwechsels bei Intensivpatienten

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Aspekte der Arzneitherapie bei Intensivpatienten

Zusammenfassung

Viele Arzneimittel können aufgrund ihrer geringen Wasserlöslichkeit nicht über die Nieren eliminiert werden. Sie unterliegen daher einem Metabolismus, der zu wasserlöslichen Stoffwechselprodukten führt. Im Mittelpunkt dieses Stoffwechsels, der überwiegend in der Leber stattfindet, steht das Cytochrom P-450, durch das Arzneimittel oxidativ verändert werden.

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  1. Beratungsstelle für Vergiftungserscheinungen, Pulsstraße 3-7, D-1000, Berlin 19, Germany

    G. Heinemeyer

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  1. G. Heinemeyer
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© 1988 Springer-Verlag Berlin Heidelberg

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Heinemeyer, G. (1988). Hemmung und Induktion des Arzneimittelstoffwechsels bei Intensivpatienten. In: Aspekte der Arzneitherapie bei Intensivpatienten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71694-2_3

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  • DOI: https://doi.org/10.1007/978-3-642-71694-2_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-17261-1

  • Online ISBN: 978-3-642-71694-2

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