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The Molecular Basis of Adaptation in Drosophila

The Role of Cytochrome P450s

  • Chapter
Evolutionary Biology

Part of the book series: Evolutionary Biology ((EBIO,volume 30))

Abstract

In the field of population genetics, genetic variation is of primary importance because it serves as the basis for evolutionary adaptation. Adaptation, another primary concern in population genetics, and one where Bruce Wallace has made numerous scientific contributions, refers to the integration of the phenotype into its environment (Hartl and Clark, 1989). With the advent of the techniques of molecular genetics, we are now able to look at genetic variation at the DNA level. Although this higher resolution provides a wealth of information and, in some cases, can shed light on previously intractable questions, it is certainly one step more removed from the phenotype. It also can quickly become overwhelming: regulatory variation versus variation in structural genes, and the complexity of mapping genotypes into phenotypes especially for quantitative traits, all in order to get at the genetic basis of an adaptation, seems impossibly intricate. The question then is, how can we best make progress in this scientific arena? One reasonable solution is to very carefully select an amiable system in which to work. Such a system should involve an organism that is genetically tractable and genes whose function in a natural environment can be investigated.

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Authors and Affiliations

  1. Department of Biological Sciences, University of Denver, Denver, Colorado, 80208, USA

    James C. Fogleman & Phillip B. Danielson

  2. Section of Genetics and Development, Cornell University, Ithaca, New York, 14853, USA

    Ross J. Macintyre

Authors
  1. James C. Fogleman
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  2. Phillip B. Danielson
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  3. Ross J. Macintyre
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Editor information

Editors and Affiliations

  1. Queens College, City University of New York, Flushing, New York, USA

    Max K. Hecht

  2. Cornell University, Ithaca, New York, USA

    Ross J. Macintyre

  3. University of California, Riverside, Riverside, California, USA

    Michael T. Clegg

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© 1998 Springer Science+Business Media New York

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Fogleman, J.C., Danielson, P.B., Macintyre, R.J. (1998). The Molecular Basis of Adaptation in Drosophila . In: Hecht, M.K., Macintyre, R.J., Clegg, M.T. (eds) Evolutionary Biology. Evolutionary Biology, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1751-5_2

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  • DOI: https://doi.org/10.1007/978-1-4899-1751-5_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1753-9

  • Online ISBN: 978-1-4899-1751-5

  • eBook Packages: Springer Book Archive

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