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Structure-Activity Correlations for the Ferric Uptake Regulation (FUR) Repressor Protein of Escherichia Coli K12

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Iron Biominerals

Abstract

The purpose of this chapter will be to give an overview of certain features of microbial iron metabolism and to record what is known at the moment of writing regarding the molecular mechanism of regulation of high affinity iron absorption in Escherichia coli K-12. Evidence obtained by chemical modification experiments suggests that thiol groups may play a role in the activity of a protein (Fur) regulating iron absorption in this bacterial species.

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© 1991 Springer Science+Business Media New York

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del Cardayre, S., Neilands, J.B. (1991). Structure-Activity Correlations for the Ferric Uptake Regulation (FUR) Repressor Protein of Escherichia Coli K12. In: Frankel, R.B., Blakemore, R.P. (eds) Iron Biominerals. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3810-3_28

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  • DOI: https://doi.org/10.1007/978-1-4615-3810-3_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6699-7

  • Online ISBN: 978-1-4615-3810-3

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