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Behavioral Actions of Neuroleptics

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Handbook of Psychopharmacology

Abstract

The term “neuroleptic” was proposed by Jean Delay and Pierre Deniker in 1955 to the French Academy of Medicine. Delay and Deniker defined a neuroleptic as an agent which induced a syndrome of behavioral and psychic symptoms that is observed in patients after administration of chlorpromazine-like drugs. By this definition, the neuroleptic drugs are those chemical substances which produce a characteristic neuroleptic syndrome in man as, at that time, the typical effects of these drugs in animals were not known. It may be pointed out that the neuroleptic syndrome is a rather acute effect of these drugs. The long-term effect that is desired of neuroleptics is to provide a cure for schizophrenia.

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Fielding, S., Lal, H. (1978). Behavioral Actions of Neuroleptics. In: Iversen, L.L., Iversen, S.D., Snyder, S.H. (eds) Handbook of Psychopharmacology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4042-3_3

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