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Acaricide activity of the Ximenia americana L. (Olacaceae) stem bark hydroethanolic extract against Rhipicephalus (Boophilus) microplus

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Abstract

Ximenia americana L. is popularly known as a plum or wild plum, which belongs to the Olacaceae family. Rhipicephalus (Boophilus) microplus represents one of the most important bovine ectoparasites that causes damage to the livestock sector. The objective of this study was to evaluate the acaricide effect of the X. americana stem bark hydroethanolic extract (EHXA) against R. (B.) microplus and its possible modulatory action when in association with cypermethrin, through the adult immersion test. The in vitro acaricide activity of the extract over R. (B.) microplus engorged females was tested using concentrations ranging from 5 to 80 mg mL− 1, which resulted in mortalities between 13.34 and 100 %, with a posture index (PI) between 0.038 and 0.226 and a posture inhibition index (PII) between 0.87 and 83.33 %. The modulatory effect of the EHXA (1.58 mg mL− 1) resulted in mortality between 0 and 46.6 %, with a posture index of 0.221 to 0.139 and a posture inhibition index between 3.01 and 38.49 %. The acaricide activity of the EHXA and its action on oviposition was demonstrated for the first time in this study, demonstrating the potential use of this extract as an auxiliary therapy in R. (B.) microplus control.

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Acknowledgements

This work was supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES—Finance Code 001), National Council for Scientific and Technological Development (CNPq), Cearense Foundation to Support Scientific and Technological Development (FUNCAP), and Financier of Studies and Projects (FINEP).

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Authors and Affiliations

  1. Laboratory of Pharmacology and Molecular Chemistry (LFQM), Regional University of Cariri-URCA, Crato, Ceará, Brazil

    Roger Henrique Sousa da Costa, Anita Oliveira Brito Pereira Bezerra Martins, Maria Rayane Correia de Oliveira & Irwin Rose Alencar de Menezes

  2. Program in Biotechnology-Northeast Biotechnology Network (RENORBIO), State University of Ceará (UECE), Fortaleza, Ceará, Brazil

    Maria Rayane Correia de Oliveira

  3. Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri-URCA, Crato, Ceará, Brazil

    Isabel Sousa Alcântara

  4. Agricultural Defense Agency of the State of Ceará-ADAGRI, Crato, Ceará, Brazil

    Felipe Francelino Ferreira

  5. Federal Institute of Education Science and Technology of Ceará (IFCE - Campus Crato), Crato, Ceará, Brazil

    Francisca Fabiana Costa dos Santos

  6. Natural Products Pharmacology Laboratory (LFPN), Department of Biological Chemistry, Regional University of Cariri-URCA, Crato, Ceará, Brazil

    Gyllyandeson de Araújo Delmondes

  7. Laboratory of Bioprospecting in the Semi-Arid and Alternative Methods (LABSEMA), Department of Biological Chemistry, Regional University of Cariri-URCA, Crato, Ceará, Brazil

    Francisco Assis Bezerra da Cunha

  8. Laboratory of Microbiology and Molecular Biology (LMBM), Department of Biological Chemistry, Regional University of Cariri-URCA, Crato, Ceará, Brazil

    Henrique Douglas Melo Coutinho

  9. Laboratory of Pharmacology and Molecular Chemistry (LFQM), Regional University of Cariri-URCA, CE, Crato, Brasil

    Henrique Douglas Melo Coutinho & Irwin Rose Alencar de Menezes

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  1. Roger Henrique Sousa da Costa
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Contributions

Roger Henrique Sousa da Costa, Felipe Francelino Ferreira, Francisca Fabiana Costa dos Santos: Conceptualization, Methodology, Roger Henrique Sousa da Costa,: Writing- Original draft preparation. Francisco Assis Bezerra da Cunha: Visualization; Roger Henrique Sousa da Costa, Maria Rayane Correia de Oliveira, Isabel Sousa Alcântara: Investigation. Irwin Rose Alencar de Menezes, Henrique Douglas Melo Coutinho: Supervision.; Gyllyandeson de Araújo Delmondes: Validation.:Anita Oliveira Brito Pereira Bezerra Martins: Writing- Reviewing and Editing.

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Correspondence to Irwin Rose Alencar de Menezes.

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da Costa, R.H.S., Martins, A.O.B.P.B., de Oliveira, M.R.C. et al. Acaricide activity of the Ximenia americana L. (Olacaceae) stem bark hydroethanolic extract against Rhipicephalus (Boophilus) microplus. Biologia 77, 1667–1674 (2022). https://doi.org/10.1007/s11756-021-00862-2

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