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Association of activities of daily living, mobility and balance ability, and symptoms of Parkinson’s disease with the masses and amounts of intramuscular non-contractile tissue of the trunk and lower extremity muscles in patients with Parkinson’s disease

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Abstract

Purpose

We examined the association of activities of daily living (ADL), mobility and balance ability, and symptoms of Parkinson’s disease (PD) with the masses and amounts of intramuscular non-contractile tissue of the trunk and lower extremity muscles in patients with PD.

Methods

The subjects were 11 community-dwelling patients with PD. ADL were assessed using the Functional Independence Measure. Mobility capacity was assessed based on measurement of maximal walking speed and timed up-and-go time, while balance ability was evaluated based on measurement of one-legged stance time. The symptoms of PD were assessed based on measurement of the Hoehn and Yahr stage and Unified Parkinson’s Disease Rating Scale. Muscle thickness (MT) and echo intensity (EI) of the trunk and lower extremity muscles were also measured using an ultrasound imaging device.

Results

Partial correlation analysis revealed an association between reduced ADL and increased EI of the lumbar erector spinae muscle; reduced mobility capacity and increased EI of the rectus abdominis and gluteus minimus muscles; and reduced balance ability and decreased MT of the lumbar erector spinae muscle and increased EI of the lumbar erector spinae, semitendinosus, and tibialis posterior muscles. Partial correlation analysis also showed an association between symptoms of severe PD and decreased MT of the tibialis anterior muscles and increased EI of the lumbar erector spinae, gluteus minimus, and tibialis posterior muscles.

Conclusion

The properties of the trunk and lower extremity muscles may be critical for ADL, mobility and balance ability, and symptoms of PD in patients with PD.

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Acknowledgements

The authors wish to thank all of the individuals who participated in the present study.

Funding

On behalf of all authors, the corresponding author states that there are no funding sources.

Author information

Authors and Affiliations

  1. Department of Physical Therapy, Takasaki University of Health and Welfare, 501 Nakaorui-machi, Takasaki, Gunma, 370-0033, Japan

    Mitsuhiro Masaki

  2. Department of Rehabilitation, Iwamuro Rehabilitation Hospital, 772-1 Iwamuronsen, Nishikan-ku, Niigata, Niigata, 953-0104, Japan

    Moeka Takeuchi

  3. Department of Rehabilitation, Tsunoda Hospital, 675-4 Kamishinden, Tamamura-machi, Sawagun, Gunma, 370-1133, Japan

    Maki Kasahara

  4. Tsutsumi Orthopaedic Clinic, 3-8-24 Terauchidonosawa, Akita, Akita, 011-0901, Japan

    Kota Minakawa

  5. Department of Rehabilitation, Sawarabi Medical Welfare Center, 168-1 Oyagi-machi, Takasaki, Gunma, 370-0072, Japan

    Yukika Inagaki

  6. Department of Rehabilitation, Sannocho Hospital, 5-2-30 Hon-cho, Sanjo, Niigata, 955-0071, Japan

    Yukine Ogawa

  7. Suzuki Otolaryngology Clinic, 6-5-37 Meike, Chuo-ku, Niigata, Niigata, 950-0941, Japan

    Yoshino Sato

  8. Department of Rehabilitation, Takeda General Hospital, 3-27 Yamaga-machi, Aizuwakamatsu, Fukushima, 965-8585, Japan

    Minori Yokota

  9. Piapupu Sports, 2-11-18 Dekijima, Chuo-ku, Niigata, Niigata, 950-0962, Japan

    Seina Maruyama

  10. Department of Rehabilitation, National Hospital Organization Nishiniigata Chuo Hospital, 1-14-1 Masago, Nishi-ku, Niigata, Niigata, 950-2085, Japan

    Shunsuke Obinata

Authors
  1. Mitsuhiro Masaki
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  2. Moeka Takeuchi
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  3. Maki Kasahara
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  4. Kota Minakawa
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  5. Yukika Inagaki
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  6. Yukine Ogawa
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  7. Yoshino Sato
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  8. Minori Yokota
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  9. Seina Maruyama
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  10. Shunsuke Obinata
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Contributions

All authors conceived and designed the research. MM, MT, MK, KM, YI, YO, YS, MY, SM, and SO conducted experiments. MM, MT, and MK analyzed data. MM and MT wrote the manuscript. All authors read and approved the manuscript.

Corresponding author

Correspondence to Mitsuhiro Masaki.

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Conflict of interest

On behalf of all authors, the corresponding author states that there are no conflicts of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Masaki, M., Takeuchi, M., Kasahara, M. et al. Association of activities of daily living, mobility and balance ability, and symptoms of Parkinson’s disease with the masses and amounts of intramuscular non-contractile tissue of the trunk and lower extremity muscles in patients with Parkinson’s disease. J Med Ultrasonics 50, 551–560 (2023). https://doi.org/10.1007/s10396-023-01356-1

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  • DOI: https://doi.org/10.1007/s10396-023-01356-1

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