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Recent advances of nanomaterials for non-steroidal anti-inflammatory drugs removal from wastewater: a critical review

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Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most widely consumed drugs. These drugs often end up in our water systems because human bodies cannot fully metabolize them, and the residual amounts are excreted through urine or feces. Their ubiquitous presence in wastewater poses various degrees of risk to non-targeted species. Cognizant of the situation, this review encompasses and probes into the occurrence, sources, removal strategies, and legislations pertaining to NSAIDs in aqueous environments. A comprehensive and state-of-the-art overview of the utilization of multifunctional nanomaterials such as nanoadsorbent, metal–organic frameworks, semiconductor-based nanocatalysts, and biologically modified nanoparticles for the efficient removal of NSAIDs in water has been discussed. Furthermore, the review is an output of a conscientious effort to bring attention to the current global guidelines, policies, and directives. The review also entails recommendations for future studies toward managing pharmaceutical contaminants in the environment. We believe that the present study is useful for environmentalists, legislators and policymakers, scientists, industrialists, and organizations working toward sustainable development goals.

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Acknowledgements

J.M. would like to thank help and support received from Applied Sciences Cluster, at School of Engineering, University of Petroleum and Energy Studies, Dehradun, India. J.S., S.N, and M.J. are thankful and grateful to Directors of Amity Institute of Biotechnology and Amity Institute of Nanotechnology, Amity University, Noida, for their support and assistance.

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This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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  1. Jimmy Mangalam and Jyoti Sharma have contributed equally to this work.

Authors and Affiliations

  1. Applied Sciences Cluster, School of Engineering, University of Petroleum and Energy Studies, Bidholi Via Premnagar, Dehradun, Uttarakhand, 248007, India

    Jimmy Mangalam

  2. Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201313, India

    Jyoti Sharma & Subhasha Nigam

  3. Amity Institute of Nanotechnology, Amity University, Noida, Uttar Pradesh, 201313, India

    Mahima Sharma & Monika Joshi

  4. Mads Clausen Institute, NanoSYD, University of Southern Denmark, Alsion 2, 6400, Sønderborg, Denmark

    Yogendra Kumar Mishra

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Contributions

JM and JS contributed to conceptualization, data curation, formal analysis, validation, visualization, writing—review, and editing. MS performed validation, visualization, writing—review, and editing. YKM performed formal analysis, writing—review, editing, and supervision. SN contributed to conceptualization, data curation, formal analysis, investigation, methodology, validation, visualization, supervision, resources, writing—review, and editing. MJ contributed to conceptualization, data curation, formal analysis, investigation, validation, visualization, supervision, resources, writing—review, and editing.

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Correspondence to Subhasha Nigam or Monika Joshi.

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Mangalam, J., Sharma, J., Sharma, M. et al. Recent advances of nanomaterials for non-steroidal anti-inflammatory drugs removal from wastewater: a critical review. Clean Techn Environ Policy (2024). https://doi.org/10.1007/s10098-023-02701-1

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