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White Coat and Masked Hypertension

Pediatric Hypertension

Abstract

Utilization of out-of-office blood pressure techniques is endorsed in international pediatric blood pressure guidelines to allow identification of white coat hypertension (WCH) and masked hypertension (MH) in children and adolescents. This chapter will provide an in-depth discussion of the different clinical definitions of these diagnoses and the evolution of these definitions over time. The chapter will also cover the reported prevalence rates of WCH and MH, including how they may differ depending on the clinical setting as well as the patient population. The chapter will also review the clinical implications of both WCH and MH for both healthy children and those with various chronic medical conditions. Lastly, the chapter will conclude by considering future directions for clinical research into these entities in diverse pediatric populations.

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References

  • Abdalla M, Goldsmith J, Muntner P, Diaz KM, Reynolds K, Schwartz JE, Shimbo D (2016) Is isolated nocturnal hypertension a reproducible phenotype? Am J Hypertens 29:33–38

    Article  PubMed  Google Scholar 

  • Arikanoğlu E, Tabel Y, Selimoğlu A (2022) Evaluation of arterial hypertension by ambulatory blood pressure monitoring in pediatric liver transplant recipients. Blood Press Monit 27:39–42

    Article  PubMed  Google Scholar 

  • Asayama K, Thijs L, Li Y, Gu YM, Hara A, Liu YP, Zhang Z, Wei FF, Lujambio I, Mena LJ, Boggia J, Hansen TW, Bjorklund-Bodegard K, Nomura K, Ohkubo T, Jeppesen J, Torp-Pedersen C, Dolan E, Stolarz-Skrzypek K, Malyutina S, Casiglia E, Nikitin Y, Lind L, Luzardo L, Kawecka-Jaszcz K, Sandoya E, Filipovsky J, Maestre GE, Wang J, Imai Y, Franklin SS, O’Brien E, Staessen JA, Investigators International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes (2014) Setting thresholds to varying blood pressure monitoring intervals differentially affects risk estimates associated with white-coat and masked hypertension in the population. Hypertension 64:935–942

    Article  CAS  PubMed  Google Scholar 

  • Becker AM, Goldberg JH, Henson M, Ahn C, Tong L, Baum M, Buchanan GR (2014) Blood pressure abnormalities in children with sickle cell anemia. Pediatr Blood Cancer 61:518–522

    Article  PubMed  Google Scholar 

  • Borchert-Morlins B, Memaran N, Sauer M, Maecker-Kolhoff B, Sykora KW, Blote R, Bauer E, Schmidt BMW, Melk A, Beier R (2018) Cardiovascular risk factors and subclinical organ damage after hematopoietic stem cell transplantation in pediatric age. Bone Marrow Transplant 53:983–992

    Article  PubMed  CAS  Google Scholar 

  • Chaudhuri A, Sutherland SM, Begin B, Salsbery K, McCabe L, Potter D, Alexander SR, Wong CJ (2011) Role of twenty-four-hour ambulatory blood pressure monitoring in children on dialysis. Clin J Am Soc Nephrol 6:870–876

    Article  PubMed  PubMed Central  Google Scholar 

  • Cuspidi C, Rescaldani M, Tadic M, Sala C, Grassi G, Mancia G (2015a) White-coat hypertension, as defined by ambulatory blood pressure monitoring, and subclinical cardiac organ damage: a meta-analysis. J Hypertens 33:24–32

    Article  CAS  PubMed  Google Scholar 

  • Cuspidi C, Sala C, Tadic M, Rescaldani M, Grassi G, Mancia G (2015b) Is white-coat hypertension a risk factor for carotid atherosclerosis? A review and meta-analysis. Blood Press Monit 20:57–63

    Article  PubMed  Google Scholar 

  • Cuspidi C, Tadic M, Sala C (2019) Targeting nocturnal hypertension: the emerging role of home blood pressure. Am J Hypertens 32:727–729

    Article  PubMed  Google Scholar 

  • Davis ML, Ferguson MA, Zachariah JP (2014) Clinical predictors and impact of ambulatory blood pressure monitoring in pediatric hypertension referrals. J Am Soc Hypertens 8:660–667

    Article  PubMed  PubMed Central  Google Scholar 

  • Di Salvo G, Castaldi B, Baldini L, Gala S, del Gaizo F, D’Andrea A, Limongelli G, D’Aiello AF, Scognamiglio G, Sarubbi B, Pacileo G, Russo MG, Calabro R (2011) Masked hypertension in young patients after successful aortic coarctation repair: impact on left ventricular geometry and function. J Hum Hypertens 25:739–745

    Article  PubMed  Google Scholar 

  • Ettinger LM, Freeman K, DiMartino-Nardi JR, Flynn JT (2005) Microalbuminuria and abnormal ambulatory blood pressure in adolescents with type 2 diabetes mellitus. J Pediatr 147:67–73

    Article  CAS  PubMed  Google Scholar 

  • Fan HQ, Li Y, Thijs L, Hansen TW, Boggia J, Kikuya M, Bjorklund-Bodegard K, Richart T, Ohkubo T, Jeppesen J, Torp-Pedersen C, Dolan E, Kuznetsova T, Stolarz-Skrzypek K, Tikhonoff V, Malyutina S, Casiglia E, Nikitin Y, Lind L, Sandoya E, Kawecka-Jaszcz K, Imai Y, Ibsen H, O’Brien E, Wang J, Staessen JA, Investigators International Database on Ambulatory Blood Pressure In Relation to Cardiovascular Outcomes (2010) Prognostic value of isolated nocturnal hypertension on ambulatory measurement in 8711 individuals from 10 populations. J Hypertens 28:2036–2045

    Article  CAS  PubMed  Google Scholar 

  • Flynn JT, Daniels SR, Hayman LL, Maahs DM, McCrindle BW, Mitsnefes M, Zachariah JP, Urbina EM, Hypertension American Heart Association Atherosclerosis, and Young Obesity in Youth Committee of the Council on Cardiovascular Disease in the (2014) Update: ambulatory blood pressure monitoring in children and adolescents: a scientific statement from the American Heart Association. Hypertension 63:1116–1135

    Article  CAS  PubMed  Google Scholar 

  • Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Flinn SK, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thaker VV, Urbina EM, Screening Subcommittee on, and Children Management of High Blood Pressure In (2017) Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics 140(3):e20171904

    Google Scholar 

  • Fossali E, Signorini E, Intermite RC, Casalini E, Lovaria A, Maninetti MM, Rossi LN (2000) Renovascular disease and hypertension in children with neurofibromatosis. Pediatr Nephrol 14:806–810

    Article  CAS  PubMed  Google Scholar 

  • Franklin SS, Thijs L, Asayama K, Li Y, Hansen TW, Boggia J, Jacobs L, Zhang Z, Kikuya M, Bjorklund-Bodegard K, Ohkubo T, Yang WY, Jeppesen J, Dolan E, Kuznetsova T, Stolarz-Skrzypek K, Tikhonoff V, Malyutina S, Casiglia E, Nikitin Y, Lind L, Sandoya E, Kawecka-Jaszcz K, Filipovsky J, Imai Y, Wang JG, O’Brien E, Staessen JA, Investigators I (2016) The cardiovascular risk of white-coat hypertension. J Am Coll Cardiol 68:2033–2043

    Article  PubMed  Google Scholar 

  • Fudge EB, Constantacos C, Fudge JC, Davenport M (2014) Improving detection of hypertension in girls with turner syndrome using ambulatory blood pressure monitoring. Horm Res Paediatr 81:25–31

    Article  CAS  PubMed  Google Scholar 

  • Glackin S, Islam N, Henderson AM, Dionne JM, Harris KC, Panagiotopoulos C, Devlin AM (2020) Ambulatory blood pressure and carotid intima media thickness in children with type 1 diabetes. Pediatr Diabetes 21:358–365

    Article  PubMed  Google Scholar 

  • Grassi G, Seravalle G, Trevano FQ, Dell’oro R, Bolla G, Cuspidi C, Arenare F, Mancia G (2007) Neurogenic abnormalities in masked hypertension. Hypertension 50:537–542

    Article  CAS  PubMed  Google Scholar 

  • Hamdani G, Nehus EJ, Hooper DK, Mitsnefes MM (2016) Masked hypertension and allograft function in pediatric and young adults kidney transplant recipients. Pediatr Transplant 20:1026–1031

    Article  CAS  PubMed  Google Scholar 

  • Hamdani G, Mitsnefes MM, Flynn JT, Becker RC, Daniels S, Falkner BE, Ferguson M, Hooper SR, Hanevold CD, Ingelfinger JR, Lande M, Martin LJ, Meyers KE, Rosner B, Samuels J, Urbina EM (2021) Pediatric and adult ambulatory blood pressure thresholds and blood pressure load as predictors of left ventricular hypertrophy in adolescents. Hypertension 78:30–37

    Article  CAS  PubMed  Google Scholar 

  • Huang Y, Huang W, Mai W, Cai X, An D, Liu Z, Huang H, Zeng J, Hu Y, Xu D (2017) White-coat hypertension is a risk factor for cardiovascular diseases and total mortality. J Hypertens 35:677–688

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Huang Z, Sharman JE, Fonseca R, Park C, Chaturvedi N, Davey Smith G, Howe LD, Lawlor DA, Hughes AD, Schultz MG (2020) Masked hypertension and submaximal exercise blood pressure among adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC). Scand J Med Sci Sports 30:25–30

    Article  PubMed  Google Scholar 

  • Jardim TV, Carneiro CS, Morais P, Roriz V, Mendonça KL, Nascente FM, Póvoa TIR, Barroso WKS, Sousa ALL, Jardim PCV (2018a) White-coat, masked and sustained hypertension detected by home blood pressure monitoring in adolescents: prevalence and associated factors. Blood Press 27:151–157

    Article  PubMed  Google Scholar 

  • Jardim TV, de Souza Carneiro C, Morais P, Mendonca KL, Povoa TIR, Nascente FM, Roriz V, Barroso WKS, Sousa ALL, Jardim PCV (2018b) Home blood pressure normalcy in non-European adolescents. J Hypertens 36:61–68

    Article  CAS  PubMed  Google Scholar 

  • Kang KT, Chiu SN, Weng WC, Lee PL, Hsu WC (2017) Comparisons of office and 24-Hour ambulatory blood pressure monitoring in children with obstructive sleep apnea. J Pediatr 182(177-83):e2

    Google Scholar 

  • Kavey RE, Kveselis DA, Atallah N, Smith FC (2007) White coat hypertension in childhood: evidence for end-organ effect. J Pediatr 150:491–497

    Article  PubMed  Google Scholar 

  • Kollias A, Dafni M, Poulidakis E, Ntineri A, Stergiou GS (2014) Out-of-office blood pressure and target organ damage in children and adolescents: a systematic review and meta-analysis. J Hypertens 32:2315–2331; discussion 31

    Article  CAS  PubMed  Google Scholar 

  • Kollios K, Nika T, Kotsis V, Chrysaidou K, Antza C, Stabouli S (2021) Arterial stiffness in children and adolescents with masked and sustained hypertension. J Hum Hypertens 35:85–93

    Article  PubMed  Google Scholar 

  • Krmar RT, Holtback U, Bergh A, Svensson E, Wuhl E (2015) Oscillometric casual blood pressure normative standards for Swedish children using ABPM to exclude casual hypertension. Am J Hypertens 28:459–468

    Article  PubMed  Google Scholar 

  • La Scola C, Marra G, Ammenti A, Pasini A, Taroni F, Bertulli C, Morello W, Ceccoli M, Mencarelli F, Guarino S, Puccio G, Montini G (2020) Born with a solitary kidney: at risk of hypertension. Pediatr Nephrol 35:1483–1490

    Article  PubMed  PubMed Central  Google Scholar 

  • Lama G, Graziano L, Calabrese E, Grassia C, Rambaldi PF, Cioce F, Tedesco MA, Di Salvo G, Esposito-Salsano M (2004) Blood pressure and cardiovascular involvement in children with neurofibromatosis type1. Pediatr Nephrol 19:413–418

    Article  PubMed  Google Scholar 

  • Lande MB, Meagher CC, Fisher SG, Belani P, Wang H, Rashid M (2008) Left ventricular mass index in children with white coat hypertension. J Pediatr 153:50–54

    Article  PubMed  PubMed Central  Google Scholar 

  • Lee SH, Kim JH, Kang MJ, Lee YA, Won Yang S, Shin CH (2011) Implications of nocturnal hypertension in children and adolescents with type 1 diabetes. Diabetes Care 34:2180–2185

    Article  PubMed  PubMed Central  Google Scholar 

  • Lee MG, Allen SL, Kawasaki R, Kotevski A, Koleff J, Kowalski R, Cheung MM, Konstantinov IE, Brizard CP, d’Udekem Y (2015) High prevalence of hypertension and end-organ damage late after coarctation repair in normal arches. Ann Thorac Surg 100:647–653

    Article  PubMed  Google Scholar 

  • Litwin M, Niemirska A, Ruzicka M, Feber J (2009) White coat hypertension in children: not rare and not benign? J Am Soc Hypertens 3:416–423

    Article  PubMed  Google Scholar 

  • Lurbe E, Redon J, Kesani A, Pascual JM, Tacons J, Alvarez V, Batlle D (2002) Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes. N Engl J Med 347:797–805

    Article  CAS  PubMed  Google Scholar 

  • Lurbe E, Torro I, Alvarez V, Nawrot T, Paya R, Redon J, Staessen JA (2005) Prevalence, persistence, and clinical significance of masked hypertension in youth. Hypertension 45:493–498

    Article  CAS  PubMed  Google Scholar 

  • Lurbe E, Agabiti-Rosei E, Cruickshank JK, Dominiczak A, Erdine S, Hirth A, Invitti C, Litwin M, Mancia G, Pall D, Rascher W, Redon J, Schaefer F, Seeman T, Sinha M, Stabouli S, Webb NJ, Wuhl E, Zanchetti A (2016) 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents. J Hypertens 34:1887–1920

    Article  CAS  PubMed  Google Scholar 

  • Lurbe E, Torro I, Alvarez J, Aguilar F, Mancia G, Redon J, Redon P (2019) Impact of ESH and AAP hypertension guidelines for children and adolescents on office and ambulatory blood pressure-based classifications. J Hypertens 37:2414–2421

    Article  CAS  PubMed  Google Scholar 

  • Macumber I (2017) Ambulatory blood pressure monitoring in children and adolescents: a review of recent literature and new guidelines. Curr Hypertens Rep 19:96

    Article  PubMed  Google Scholar 

  • Maggio AB, Aggoun Y, Marchand LM, Martin XE, Herrmann F, Beghetti M, Farpour-Lambert NJ (2008) Associations among obesity, blood pressure, and left ventricular mass. J Pediatr 152:489–493

    Article  PubMed  Google Scholar 

  • Mancia G, Bombelli M, Facchetti R, Madotto F, Quarti-Trevano F, Polo Friz H, Grassi G, Sega R (2009) Long-term risk of sustained hypertension in white-coat or masked hypertension. Hypertension 54:226–232

    Article  CAS  PubMed  Google Scholar 

  • Mancia G, Bombelli M, Seravalle G, Grassi G (2011) Diagnosis and management of patients with white-coat and masked hypertension. Nat Rev Cardiol 8:686–693

    Article  CAS  PubMed  Google Scholar 

  • Mancia G, Facchetti R, Grassi G, Bombelli M (2015) Adverse prognostic value of persistent office blood pressure elevation in white coat hypertension. Hypertension 66:437–444

    Article  CAS  PubMed  Google Scholar 

  • Mancia G, Facchetti R, Bombelli M, Cuspidi C, Grassi G (2021) White-coat hypertension: pathophysiological and clinical aspects: excellence award for hypertension research 2020. Hypertension 78:1677–1688

    Article  CAS  PubMed  Google Scholar 

  • Meininger JC, Gallagher MR, Eissa MA, Nguyen TQ, Chan W (2014) Sleep duration and its association with ambulatory blood pressure in a school-based, diverse sample of adolescents. Am J Hypertens 27:948–955

    Article  PubMed  PubMed Central  Google Scholar 

  • Merchant K, Shah PP, Singer P, Castellanos L, Sethna CB (2021) Comparison of pediatric and adult ambulatory blood pressure monitoring criteria for the diagnosis of hypertension and detection of left ventricular hypertrophy in adolescents. J Pediatr 230:161–166

    Article  PubMed  Google Scholar 

  • Mitsnefes M, Flynn J, Cohn S, Samuels J, Blydt-Hansen T, Saland J, Kimball T, Furth S, Warady B, C. KiD Study Group (2010) Masked hypertension associates with left ventricular hypertrophy in children with CKD. J Am Soc Nephrol 21:137–144

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mitsnefes M, Flynn JT, Brady T, Baker-Smith C, Daniels SR, Hayman LL, Tran A, Zachariah JP, Urbina EM (2021) Pediatric ambulatory blood pressure classification: the case for a change. Hypertension 78:1206–1210

    Article  CAS  PubMed  Google Scholar 

  • Miyashita Y, Flynn JT, Hanevold CD (2017) Diagnosis and management of white-coat hypertension in children and adolescents: a Midwest Pediatric Nephrology Consortium study. J Clin Hypertens (Greenwich) 19:884–889

    Article  Google Scholar 

  • Miyashita Y, Hanevold CD, Faino A, Scher J, Lande MB, Yamaguchi I, Hernandez J, Acosta A, Weaver DJ, Thomas J, Kallash M, Ferguson MA, Patel KN, South A, Kelton M, Flynn JT (2020) Abstract 5: white coat hypertension stability in children and adolescents: Pediatric Nephrology Research Consortium Study. Hypertension 76:A5

    Article  Google Scholar 

  • Munakata M (2018) Clinical significance of stress-related increase in blood pressure: current evidence in office and out-of-office settings. Hypertens Res 41:553–569

    Article  PubMed  Google Scholar 

  • National High Blood Pressure Education Program Working Group on High Blood Pressure in, Children, and Adolescents (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114:555–576

    Article  Google Scholar 

  • O’Sullivan JJ, Derrick G, Darnell R (2002) Prevalence of hypertension in children after early repair of coarctation of the aorta: a cohort study using casual and 24 hour blood pressure measurement. Heart 88:163–166

    Article  PubMed  PubMed Central  Google Scholar 

  • Ogedegbe G, Spruill TM, Sarpong DF, Agyemang C, Chaplin W, Pastva A, Martins D, Ravenell J, Pickering TG (2013) Correlates of isolated nocturnal hypertension and target organ damage in a population-based cohort of African Americans: the Jackson Heart Study. Am J Hypertens 26:1011–1016

    Article  PubMed  PubMed Central  Google Scholar 

  • Pall D, Juhasz M, Lengyel S, Molnar C, Paragh G, Fulesdi B, Katona E (2010) Assessment of target-organ damage in adolescent white-coat and sustained hypertensives. J Hypertens 28:2139–2144

    Article  CAS  PubMed  Google Scholar 

  • Pierdomenico SD, Pierdomenico AM, Cuccurullo F (2014) Morning blood pressure surge, dipping, and risk of ischemic stroke in elderly patients treated for hypertension. Am J Hypertens 27:564–570

    Article  PubMed  Google Scholar 

  • Punjabi NM, Caffo BS, Goodwin JL, Gottlieb DJ, Newman AB, O’Connor GT, Rapoport DM, Redline S, Resnick HE, Robbins JA, Shahar E, Unruh ML, Samet JM (2009) Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med 6:e1000132

    Article  PubMed  PubMed Central  Google Scholar 

  • Rahman M, Wang X, Bundy JD, Charleston J, Cohen D, Cohen J, Drawz PE, Ghazi L, Horowitz E, Lash JP, Schrauben S, Weir MR, Xie D, Townsend RR, Cric Study Investigators (2020) Prognostic significance of ambulatory BP monitoring in CKD: a report from the Chronic Renal Insufficiency Cohort (CRIC) Study. J Am Soc Nephrol 31:2609–2621

    Article  PubMed  PubMed Central  Google Scholar 

  • Samuels J, Ng D, Flynn JT, Mitsnefes M, Poffenbarger T, Warady BA, Furth S, Group Chronic Kidney Disease in Children Study (2012) Ambulatory blood pressure patterns in children with chronic kidney disease. Hypertension 60:43–50

    Article  CAS  PubMed  Google Scholar 

  • Schaefer F, Doyon A, Azukaitis K, Bayazit A, Canpolat N, Duzova A, Niemirska A, Sozeri B, Thurn D, Anarat A, Ranchin B, Litwin M, Caliskan S, Candan C, Baskin E, Yilmaz E, Mir S, Kirchner M, Sander A, Haffner D, Melk A, Wuhl E, Shroff R, Querfeld U, C. Study Consortium (2017) Cardiovascular phenotypes in children with CKD: The 4C study. Clin J Am Soc Nephrol 12:19–28

    Article  PubMed  Google Scholar 

  • Seeman T, Simková E, Kreisinger J, Vondrák K, Dusek J, Gilík J, Feber J, Dvorák P, Janda J (2006) Control of hypertension in children after renal transplantation. Pediatr Transplant 10:316–322

    Article  CAS  PubMed  Google Scholar 

  • Seeman T, Pohl M, Palyzova D, John U (2012) Microalbuminuria in children with primary and white-coat hypertension. Pediatr Nephrol 27:461–467

    Article  PubMed  Google Scholar 

  • Sharma AP, Altamirano-Diaz L, Mohamed Ali M, Stronks K, Kirpalani A, Filler G, Norozi K (2021) Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds. J Clin Hypertens (Greenwich) 23:1947–1956

    Article  Google Scholar 

  • Shatat IF, Jakson SM, Blue AE, Johnson MA, Orak JK, Kalpatthi R (2013) Masked hypertension is prevalent in children with sickle cell disease: a Midwest Pediatric Nephrology Consortium study. Pediatr Nephrol 28:115–120

    Article  PubMed  Google Scholar 

  • Sheng CS, Li FK, Cheng YB, Wei FF, Huang JF, Guo QH, Zhang DY, Wang Y, An DW, Huang QF, Li Y, Wang JG (2020) Blood pressure and heart rate variability and baroreflex sensitivity in white-coat, masked, and sustained hypertension. Hypertens Res 43:772–780

    Article  PubMed  Google Scholar 

  • Soergel M, Kirschstein M, Busch C, Danne T, Gellermann J, Holl R, Krull F, Reichert H, Reusz GS, Rascher W (1997) Oscillometric twenty-four-hour ambulatory blood pressure values in healthy children and adolescents: a multicenter trial including 1141 subjects. J Pediatr 130:178–184

    Article  CAS  PubMed  Google Scholar 

  • Stabouli S, Kotsis V, Toumanidis S, Papamichael C, Constantopoulos A, Zakopoulos N (2005) White-coat and masked hypertension in children: association with target-organ damage. Pediatr Nephrol 20:1151–1155

    Article  PubMed  Google Scholar 

  • Stergiou GS, Alamara CV, Kalkana CB, Vaindirlis IN, Stefanidis CJ, Dacou-Voutetakis C, Mountokalakis TD (2004) Out-of-office blood pressure in children and adolescents: disparate findings by using home or ambulatory monitoring. Am J Hypertens 17:869–875

    Article  PubMed  Google Scholar 

  • Stergiou GS, Yiannes NG, Rarra VC, Panagiotakos DB (2007) Home blood pressure normalcy in children and adolescents: the Arsakeion School study. J Hypertens 25:1375–1379

    Article  CAS  PubMed  Google Scholar 

  • Stergiou GS, Rarra VC, Yiannes NG (2009) Prevalence and predictors of masked hypertension detected by home blood pressure monitoring in children and adolescents: the Arsakeion School study. Am J Hypertens 22:520–524

    Article  PubMed  Google Scholar 

  • Swartz SJ, Srivaths PR, Croix B, Feig DI (2008) Cost-effectiveness of ambulatory blood pressure monitoring in the initial evaluation of hypertension in children. Pediatrics 122:1177–1181

    Article  PubMed  Google Scholar 

  • Tainio J, Qvist E, Miettinen J, Holtta T, Pakarinen M, Jahnukainen T, Jalanko H (2015) Blood pressure profiles 5 to 10 years after transplant in pediatric solid organ recipients. J Clin Hypertens (Greenwich) 17:154–161

    Article  Google Scholar 

  • Tschumi S, Noti S, Bucher BS, Simonetti GD (2011) Is childhood blood pressure higher before or after clinic consultation? Acta Paediatr 100:775–777

    Article  PubMed  Google Scholar 

  • Valent Moric B, Jelakovic B, Vidatic I, Trutin I, Jelakovic A, Stipancic G (2020) Ambulatory blood pressure profile in office normotensive obese children: prevalence of masked hypertension and impact of parental hypertension. J Pediatr Endocrinol Metab 33:1313–1320

    Article  CAS  PubMed  Google Scholar 

  • Westerstahl M, Forss M, Persson L, Bouma K, Gustavsson T, Wuhl E, Krmar RT (2018) Hypertension outcomes and cardiovascular status in young adults with childhood-diagnosed white coat hypertension. Arch Dis Child 103:113–114

    Article  PubMed  Google Scholar 

  • Wuhl E, Witte K, Soergel M, Mehls O, Schaefer F, Hypertension German Working Group on Pediatric (2002) Distribution of 24-h ambulatory blood pressure in children: normalized reference values and role of body dimensions. J Hypertens 20:1995–2007

    Article  PubMed  Google Scholar 

  • Wuhl E, Hadtstein C, Mehls O, Schaefer F, Group Escape Trial (2004) Home, clinic, and ambulatory blood pressure monitoring in children with chronic renal failure. Pediatr Res 55:492–497

    Article  PubMed  Google Scholar 

  • Yegul-Gulnar G, Kasap-Demir B, Alparslan C, Catli G, Mutlubas F, Yavascan O, Ozkan B, Dundar BN, Aksu N (2019) Ambulatory blood pressure monitoring parameters in obese children and adolescents with masked hypertension. Blood Press Monit 24:277–283

    Article  PubMed  Google Scholar 

  • Yel S, Gunay N, Pinarbasi AS, Balaban AG, Caferoglu Z, Dursun I, Poyrazoglu MH (2021) Do children with solitary or hypofunctioning kidney have the same prevalence for masked hypertension? Pediatr Nephrol 36:1833–1841

    Article  PubMed  Google Scholar 

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Miyashita, Y., Hanevold, C. (2022). White Coat and Masked Hypertension. In: Flynn, J.T., Ingelfinger, J.R., Brady, T. (eds) Pediatric Hypertension. Springer, Cham. https://doi.org/10.1007/978-3-319-31420-4_61-1

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  1. Latest

    White Coat and Masked Hypertension
    Published:
    20 October 2022

    DOI: https://doi.org/10.1007/978-3-319-31420-4_61-2

  2. Original

    White Coat and Masked Hypertension
    Published:
    19 May 2022

    DOI: https://doi.org/10.1007/978-3-319-31420-4_61-1