Pediatric Hypertension

1. Adverse Childhood Experiences and Their Relevance to Hypertension in Children and Youth

   • Julie R. Ingelfinger

2. Ambulatory Blood Pressure Monitoring Methodology and Norms in Children

   • Elke Wühl

3. Antenatal Programming of Blood Pressure

   • Andrew M. South

4. Appendix: Highlights of the 2017 American Academy of Pediatrics Clinical Practice Guideline for the Screening and Management of High Blood Pressure in Children and Adolescents

   • Joseph T. Flynn

5. Cardiovascular Assessment of Childhood Hypertension

   • Edem Binka, Elaine M. Urbina

6. Cardiovascular Influences on Blood Pressure

   • Manish D. Sinha, Phil Chowienczyk

7. Changes in Drug Development Regulations and Their Impact on Clinical Trials

   • Elizabeth J. Thompson, Kevin D. Hill, Rachel D. Torok, Jennifer S. Li

8. Cohort Studies, Meta-analyses, and Clinical Trials in Childhood Hypertension

   • Nicholas Larkins, Jonathan Craig

9. Development of Blood Pressure Norms and Definition of Hypertension in Children

   • Bonita Falkner

10. Diagnostic Evaluation of Pediatric Hypertension

    • Nicholas Larkins, Derek Roebuck

11. Early Vascular Aging in Pediatric Hypertension Patients

    • Mieczysław Litwin

12. Endocrine Hypertension

    • Perrin C. White

13. Endothelial Dysfunction and Vascular Remodeling in Hypertension

    • Julie Goodwin

14. Epidemiology of Cardiovascular Disease in Children

    • Samuel S. Gidding

15. Epidemiology of Hypertension and Cardiovascular Disease in Children and Adolescents

    • Elyse O. Kharbanda

16. Epidemiology of Primary Hypertension in Children

    • Karen McNiece Redwine

17. Ethnic Differences in Childhood Blood Pressure

    • Joshua Samuels, Xamayta Negroni-Balasquide

18. Exercise Testing in Hypertension and Hypertension in Athletes

    • Carissa M. Baker-Smith, Takeshi Tsuda

19. Familial Aggregation of Blood Pressure and the Heritability of Hypertension

    • Sujane Kandasamy, Rahul Chanchlani

20. Hypertension Care During Emergencies and Pandemics

    • Joyce P. Samuel, Bradley K. Hyman

For the past 17 years, Pediatric Hypertension has served as the definitive reference text on hypertension in children and adolescents. Each edition has incorporated the latest research on the pathophysiology, clinical significance and management of hypertension in the young, and has incorporated the most current consensus guidelines on diagnosis and management. The years since publication of the fourth edition have seen further advances in the field that merit publication of an updated, expanded text, including:

•      Analysis of the implications of updated hypertension guidelines on identification of youth at highest cardiovascular risk
•      Additional data on the proximate effects of high blood pressure in children in adolescents
•      Further understanding of the links between high blood pressure in youth and surrogate markers of adult cardiovascular disease

The fifth edition is a readable, informative text that provides a comprehensive guide to the diagnosis, management and therapy of hypertension in children and adolescents, and presents new data that very clearly indicate that the origins of adult cardiovascular disease are rooted in pediatric hypertension. It will, as a result, be very important for therapeutic decisions and will also be highly relevant for those in internal medicine, who care for the millions of adults who have hypertension, cardiovascular disease and kidney disease. In this sense, the book fulfills the longstanding goal of showing that hypertension that begins in childhood is important to track, diagnose and treat, and that the present understanding of adult hypertension necessitates the study of blood pressure in youth.

The fifth edition has a similar structural format to the prior editions and covers all aspects of pediatric hypertension, from basic science research to the most recent clinical information.

 

• Blood Pressure Regulation
• Cardiovascular Disease
• Childhood Obesity
• Chronic Kidney Disease
• neurohumoral regulation
• endothelial dysfunction
• end-stage renal disease
• vasculitis
• renovascular HTN
• ABPM

• Department of Pediatrics, University of Washington School of Medicine, Seattle, USA

  Joseph T. Flynn

• Pediatric Nephrology Unit, Mass General for Children at MGB Harvard Medical School, Boston, USA

  Julie R. Ingelfinger

• Department of Pediatrics, Division of Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, USA

  Tammy Brady

Dr. Joseph T. Flynn MD, MS is the Dr. Robert O. Hickman Endowed Chair in Pediatric Nephrology; Professor of Pediatrics, University of Washington; and Chief, Division of Nephrology, Seattle Children's Hospital. He is an internationally recognized expert in the treatment of hypertension in children, and recently chaired the American Academy of Pediatrics Subcommittee that developed the updated clinical practice guideline on high blood pressure in children and adolescents. Dr. Flynn served on the Council of the International Pediatric Nephrology Association from 2010-2019, and also on the Council of the American Society of Pediatric Nephrology, including 2 years as ASPN President (2012-14). He currently is a Board Member of the Renal Physicians Association and a member of the Nephrology sub-board of the American Board of Pediatrics. He currently serves as one of the Editors-in-Chief of the journal Pediatric Nephrology and is a member of the editorial boards of Hypertension, Blood Pressure Monitoring and The Journal of Pediatrics. He has contributed chapters to all five editions of the Pediatric Hypertension and edited the three previous editions.

Julie R. Ingelfinger MD is professor of pediatrics at Harvard Medical School, senior consultant in pediatric nephrology at Mass General for Children at MGB, and Deputy Editor of the New England Journal of Medicine. She is an internationally recognized hypertension specialist and consultative pediatric nephrologist. Her commitment to teaching has been reflected by receiving the Henry L. Barnett award from the AAP in 2009, the Founders Award from the American Society of Pediatric Nephrology in 2012, the National Kidney Foundation’s Honors Award in 2018, the Alumni Lifetime Achievement Award from Albert Einstein College of Medicine (2018), and the Barbara T. Murphy Award from the American Society of Nephrology (2022).

Dr. Ingelfinger has been involved in studies of the intrarenal renin angiotensin aldosterone system (RAAS) for many years. Her current projects focus on the role of the intrarenal renin angiotensin system in disease states and the role of maternal diabetes in kidney development and perinatal programming.

She is interested in innovative ways to teach writing and communication and has been an editor of Pediatric Hypertension in each of its five editions.

Dr. Tammy M. Brady MD, PhD is Associate Professor of Pediatrics at Johns Hopkins University School of Medicine where she serves as Vice Chair for Clinical Research and as the Associate Director of the Welch Center for Prevention, Epidemiology and Clinical Research. She has focused her career on improving the care of children at increased cardiovascular disease risk through research and clinical innovation. She
serves as the Medical Director of the Harriet Lane Kidney Center Pediatric Hypertension Program, and she directs a multidisciplinary obesity hypertension clinic (ReNEW clinic; Reversing the Negative cardiovascular Effects of Weight). Dr. Brady is an expert in blood pressure measurement and blood pressure device validation. She is the co-chair of the Association for the Advancement of Medical Instrumentation (AAMI) Sphygmomanometer committee, the American professional society that develops American National Standards and technical reports regarding sphygmomanometer devices. She was Chair of a two-day meeting at the WHO where published guidance and specifications on blood pressure measuring devices were updated. She is also Co-chair of the American Medical Association’s Validated Device Listing Committee.

Policies and ethics