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Vitamin B6

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Bioavailability and Analysis of Vitamins in Foods

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Abstract

In 1934 György observed the appearance of a scaly dermatitis (acrodynia) in rats fed on diets free from the whole vitamin B complex and supplemented with thiamin and riboflavin. This observation led to the establishment of a ‘rat acrodynia-preventative factor’ and its designation as vitamin B6. The isolation of the pure crystalline vitamin was first reported by Lepkovsky in 1938, and the synthesis of pyridoxine was accomplished by Harris and Folkers in the following year. Discovery of the existence of pyridoxal and pyridoxamine and the recognition of their phosphorylated forms as coenzymes is largely credited to Esmond E. Snell during 1944–1948.

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    G. F. M. Ball

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Ball, G.F.M. (1998). Vitamin B6 . In: Bioavailability and Analysis of Vitamins in Foods. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3414-7_10

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