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Abstract

Cadmium is the second member of the Group IIb triad (Zn, Cd, Hg) in the periodic classification of elements. The stable state of cadmium in the natural environment is Cd(+ 2). Cadmium is silvery white and ductile with a faint blue tinge. It has a medium class b character compared to zinc and mercury. This imparts moderate covalency in bonds and high affinity for sulfhydryl groups, leading to increased lipid solubility, bioaccumulation, and toxicity. Cadmium accumulates in liver and kidney through its strong binding with cysteine residues of metallothionein. Since the metabolism of cadmium is closely related to zinc metabolism, metallothionein binds and transports both cadmium and zinc. Cadmium seems to displace zinc in many vital enzymatic reactions, causing disruption or cessation of activity.

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Moore, J.W., Ramamoorthy, S. (1984). Cadmium. In: Heavy Metals in Natural Waters. Springer Series on Environmental Management. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5210-8_3

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