Skip to main content

Anatomy of the Scrotum and Testicles

  • Chapter
  • First Online:
Urogenital Trauma: A Practical Guide
  • 188 Accesses

Abstract

The two labioscrotal swellings appear lateral to the genital tubercle during the 4th week of gestation and migrate caudally and medially in the 9th–11th weeks of gestation merging at the 12th week of gestation to form the scrotum [1, 2].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    “Gubernaculum” is a Latin word that means “steering wheel,” “helm,” or “rudder.” It was so-named by the British Surgeon John Hunter (1728–1793) in 1762 because he thought this structure directed the descending course of the testis to the scrotum. He was the younger brother of the Anatomist, William Hunter [6].

  2. 2.

    Pampiniform comes from the Latin word “pampinus,” tendril, and forma,” form or shape.

  3. 3.

    Marsupials are mammals found in Australasia, Wallacia, and the Americas. They comprise a handful of species such as kangaroos, koalas, opossums, bandicoots, wallabies, wombats, and Tasmanian devils. They do not develop a well-defined anatomical placenta but have a functional single layer of trophoblasts that produces hormones and a yolk sac. They do not have an umbilical cord, and the placentation period is shorter than for eutherians. However, this is compensated by a physiologically sophisticated and extended lactation allowing them “to exchange the umbilical cord for the teat” [32].

  4. 4.

    Eutherians or placental mammals is a group of mammals comprising nearly 4000 species, including humans, monkeys, rodents, bats, elephants, whales, shrews, armadillos, dogs, cats, sheep, cattle, horses, and so on.

References

  1. Garcia RA, Sajjad H. Anatomy, abdomen and pelvis, scrotum. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing; 2022. PMID: 31751083.

    Google Scholar 

  2. van der Werff JF, Nievelstein RA, Brands E, Luijsterburg AJ, Vermeij-Keers C. Normal development of the male anterior urethra. Teratology. 2000;61(3):172–83. https://doi.org/10.1002/(SICI)1096-9926(200003)61:3<172::AID-TERA4>3.0.CO;2-B. PMID: 10661906.

    Article  PubMed  Google Scholar 

  3. Titi-Lartey OA, Khan YS. Embryology, testicle. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing; 2022. PMID: 32491695.

    Google Scholar 

  4. Yang Y, Workman S, Wilson M. The molecular pathways underlying early gonadal development. J Mol Endocrinol. 2018; https://doi.org/10.1530/JME-17-0314. Epub ahead of print. PMID: 30042122.

  5. Silber S. Adult testis anatomy. In: Fundamentals of male infertility. Cham: Springer; 2018. https://doi.org/10.1007/978-3-319-76523-5_3.

    Chapter  Google Scholar 

  6. Hunter J. Observations on the state of the testis in the fetus, and on the hernia congenita. In: Hunter W, editor. William Hunter medical commentaries. London: Hamilton; 1762. p. 75–90.

    Google Scholar 

  7. Virtanen HE, Cortes D, Rajpert-De Meyts E, Ritzén EM, Nordenskjöld A, Skakkebaek NE, Toppari J. Development and descent of the testis in relation to cryptorchidism. Acta Paediatr. 2007;96:622–7. https://doi.org/10.1111/j.1651-2227.2007.00244.x.

    Article  PubMed  Google Scholar 

  8. Favorito LA, Costa SF, Julio-Junior HR, Sampaio FJ. The importance of the gubernaculum in testicular migration during the human fetal period. Int Braz J Urol. 2014;40(6):722–9. https://doi.org/10.1590/S1677-5538.IBJU.2014.06.02. PMID: 25615240.

    Article  PubMed  Google Scholar 

  9. Amann RP, Veeramachaneni DN. Cryptorchidism in common eutherian mammals. Reproduction. 2007;133(3):541–61. https://doi.org/10.1530/REP-06-0272. PMID: 17379650.

    Article  PubMed  CAS  Google Scholar 

  10. Harrison SM, Bush NC, Wang Y, Mucher ZR, Lorenzo AJ, Grimsby GM, Schlomer BJ, Büllesbach EE, Baker LA. Insulin-like peptide 3 (INSL3) serum concentration during human male fetal life. Front Endocrinol (Lausanne). 2019;10:596. https://doi.org/10.3389/fendo.2019.00596. PMID: 31611843; PMCID: PMC6737488.

    Article  PubMed  Google Scholar 

  11. Cavalie G, Bellier A, Marnas G, Boisson B, Robert Y, Rabattu PY, Chaffanjon P. Anatomy and histology of the scrotal ligament in adults: inconsistency and variability of the gubernaculum testis. Surg Radiol Anat. 2018;40(4):365–70. https://doi.org/10.1007/s00276-017-1904-1. Epub 2017 Jul 31. PMID: 28762084.

    Article  PubMed  CAS  Google Scholar 

  12. Kleisner K, Ivell R, Flegr J. The evolutionary history of testicular externalization and the origin of the scrotum. J Biosci. 2010;35(1):27–37. https://doi.org/10.1007/s12038-010-0005-7. PMID: 20413907.

    Article  PubMed  Google Scholar 

  13. Maguire K, Sabharwal AJ. F5 acute scrotal exploration. In: Carachi R, Agarwala S, Bradnock TJ, Lim Tan H, Cascio S, editors. Basic techniques in pediatric surgery. Berlin: Springer; 2013. https://doi.org/10.1007/978-3-642-20641-2_118.

    Chapter  Google Scholar 

  14. Patel AP. Anatomy and physiology of chronic scrotal pain. Transl Androl Urol. 2017;6(Suppl 1):S51–6. https://doi.org/10.21037/tau.2017.05.32. PMID: 28725619; PMCID: PMC5503924.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Pham SB, Hong MK, Teague JA, Hutson JM. Is the testis intraperitoneal? Pediatr Surg Int. 2005;21(4):231–9. https://doi.org/10.1007/s00383-005-1364-2. Epub 2005 Mar 9. PMID: 15756559.

    Article  PubMed  Google Scholar 

  16. McManus IC. Right-left and the scrotum in Greek sculpture. Laterality. 2004;9(2):189–99. https://doi.org/10.1080/13576500342000149. PMID: 15382717.

    Article  PubMed  CAS  Google Scholar 

  17. Jit I, Sanjeev. Weight of the testes in Northwest Indian adults. Am J Hum Biol. 1991;3(6):671–6. https://doi.org/10.1002/ajhb.1310030618. PMID: 28524284.

    Article  PubMed  Google Scholar 

  18. Wylie C. Germ cells. Cell. 1999;96(2):165–74. https://doi.org/10.1016/s0092-8674(00)80557-7. PMID: 9988212.

    Article  PubMed  CAS  Google Scholar 

  19. Griswold MD. The central role of Sertoli cells in spermatogenesis. Semin Cell Dev Biol. 1998;9(4):411–6. https://doi.org/10.1006/scdb.1998.0203. PMID: 9813187.

    Article  PubMed  CAS  Google Scholar 

  20. Mruk DD, Cheng CY. The mammalian blood-testis barrier: its biology and regulation. Endocr Rev. 2015;36(5):564–91. https://doi.org/10.1210/er.2014-1101. Epub 2015 Sep 10. Erratum in: Endocr Rev. 2015 Dec;36(6):681. Erratum in: Endocr Rev. 2016 Feb;2016(1):43. PMID: 26357922; PMCID: PMC4591527.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  21. https://openstax.org/books/anatomy-and-physiology-2e/pages/27-1-anatomy-and-physiology-of-the-testicular-reproductive-system.

  22. Hess RA. Efferent ductules: structure and function. In: Encyclopedia of reproduction. Elsevier; 2018. p. 270–8. https://doi.org/10.1016/B978-0-12-801238-3.64593-2.

    Chapter  Google Scholar 

  23. Asala S, Chaudhary SC, Masumbuko-Kahamba N, Bidmos M. Anatomical variations in the human testicular blood vessels. Ann Anat. 2001;183(6):545–9. https://doi.org/10.1016/S0940-9602(01)80064-9. PMID: 11766526.

    Article  PubMed  CAS  Google Scholar 

  24. Mostafa T, Labib I, El-Khayat Y, El-Rahman El-Shahat A, Gadallah A. Human testicular arterial supply: gross anatomy, corrosion cast, and radiologic study. Fertil Steril. 2008;90(6):2226–30. https://doi.org/10.1016/j.fertnstert.2007.10.013. Epub 2008 Jun 13. PMID: 18555239.

    Article  PubMed  Google Scholar 

  25. Wishahi MM. Anatomy of the venous drainage of the human testis: testicular vein cast, microdissection and radiographic demonstration. A new anatomical concept. Eur Urol. 1991;20(2):154–60. https://doi.org/10.1159/000471687. PMID: 1752275.

    Article  PubMed  CAS  Google Scholar 

  26. Lechter A, Lopez G, Martinez C, Camacho J. Anatomy of the gonadal veins: a reappraisal. Surgery. 1991;109(6):735–9. PMID: 2042092.

    PubMed  CAS  Google Scholar 

  27. Shafik A, Moftah A, Olfat S, Mohi-el-Din M, el-Sayed A. Testicular veins: anatomy and role in varicocelogenesis and other pathologic conditions. Urology. 1990;35(2):175–82. https://doi.org/10.1016/0090-4295(90)80071-t. PMID: 210.

    Article  PubMed  CAS  Google Scholar 

  28. Skandhan KP, Soni A, Joshi A, Avni KPS, Gupta BD. Human epididymis: structural pattern, total length and inner surface area. Urol J. 2017;84(4):215–7. https://doi.org/10.5301/uj.5000229.

    Article  Google Scholar 

  29. Firoozabadi R, Stafford P, Routt M. Risk of spermatic cord injury during anterior pelvic ring and acetabular surgery: an anatomical study. Arch Bone Jt Surg. 2015;3(4):269–73. PMID: 26550592; PMCID: PMC4628634.

    PubMed  PubMed Central  Google Scholar 

  30. Abdelmohsen SM, Osman MA, Takrouney MH, et al. A spectrum of epididymis and vas deferens anomalies among children with cryptorchidism: a retrospective multi-center study. Ann Pediatr Surg. 2021;17:55. https://doi.org/10.1186/s43159-021-00111-w.

    Article  Google Scholar 

  31. Virtanen HE, Toppari J. Epidemiology and pathogenesis of cryptorchidism. Human Reprod Update. 2008;14(1):49–58. https://doi.org/10.1093/humupd/dmm027.

    Article  CAS  Google Scholar 

  32. Renfree MB. Review: Marsupials: placental mammals with a difference. Placenta. 2010;31(Suppl):S21–6. https://doi.org/10.1016/j.placenta.2009.12.023. Epub 2010 Jan 15. PMID: 20079531.

    Article  PubMed  CAS  Google Scholar 

  33. Abbas TO, Ali M. Bilateral neonatal testicular torsion; hidden surgical nightmare. Front Pediatr. 2018;6:318. https://doi.org/10.3389/fped.2018.00318. PMID: 30525011; PMCID: PMC6256121.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Riaz-Ul-Haq M, Mahdi DE, Elhassan EU. Neonatal testicular torsion; a review article. Iran J Pediatr. 2012;22(3):281–9. PMID: 23400637; PMCID: PMC3564080

    PubMed  PubMed Central  Google Scholar 

  35. Mercer S. Agenesis or atrophy of the testis and vas deferens. Can J Surg. 1979;22(3):245–6. PMID: 35276.

    PubMed  CAS  Google Scholar 

  36. Pirgon Ö, Dündar BN. Vanishing testes: a literature review. J Clin Res Pediatr Endocrinol. 2012;4(3):116–20. https://doi.org/10.4274/Jcrpe.728. PMID: 22985611; PMCID: PMC3459158.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Bergholz R, Wenke K. Polyorchidism: a meta-analysis. J Urol. 2009;182(5):2422–7. https://doi.org/10.1016/j.juro.2009.07.063. Epub 2009 Sep 17. PMID: 19765760.

    Article  PubMed  Google Scholar 

  38. Zahirian Moghadam T, Mohseni Rad H, Zandian H, et al. Five testicles in the genital area of a thirteen-month-old baby: a case report. BMC Urol. 2020;20:128. https://doi.org/10.1186/s12894-020-00681-8.

    Article  PubMed  PubMed Central  Google Scholar 

  39. de Souza DAS, Faucz FR, Pereira-Ferrari L, Sotomaior VS, Raskin S. Congenital bilateral absence of the vas deferens as an atypical form of cystic fibrosis: reproductive implications and genetic counseling. Andrology. 2018;6(1):127–35. https://doi.org/10.1111/andr.12450. Epub 2017 Dec 7. PMID: 29216686; PMCID: PMC5745269.

    Article  PubMed  CAS  Google Scholar 

  40. Somoza I, Palacios MG, Mendez R, Vela D. Complete penoscrotal transposition: a three-stage procedure. Indian J Urol. 2012;28(4):450–2. https://doi.org/10.4103/0970-1591.105775. PMID: 23450271; PMCID: PMC3579132.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Fahmy MAB. Bifid scrotum. In: Fahmy MAB, editor. Normal and abnormal scrotum. Cham: Springer; 2022. https://doi.org/10.1007/978-3-030-83305-3_14.

    Chapter  Google Scholar 

  42. Kumar T, Vaughan R, Dangle PP. Hemangioma of the scrotal septum: a rare entity in infants with review of the literature. W V Med J. 2012;108(4):26–7. PMID: 22872962.

    PubMed  Google Scholar 

  43. Chen G, Wang X, Zhao Y, et al. Splenogonadal fusion: a case report and review of the literature. BMC Urol. 2021;21:16. https://doi.org/10.1186/s12894-021-00781-z.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Psarris A, Dimopoulou A, Iakomidis E, Zavras N, Vaos G. Hemiscrotal agenesis: a rare congenital anomaly. J Clin Diagn Res. 2017;11(8):PD19–20. https://doi.org/10.7860/JCDR/2017/28605.10507. Epub 2017 Aug 1. PMID: 28969205; PMCID: PMC5620846.

    Article  PubMed  PubMed Central  Google Scholar 

  45. Mansy M, Kotb M, Abdelmeguid Y, et al. Hemiscrotal agenesis: a novel phenotype of a rare malformation. BMC Pediatr. 2020;20:536. https://doi.org/10.1186/s12887-020-02424-y.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  46. Spagnoli A, Borsellino A, Crucianelli S, Bizzarri C, Mucciolo M, Trucchi A, Ferro F. Complete scrotal agenesis: new surgical approach using self-inflating tissue expander. Urology. 2018;112:169–71. https://doi.org/10.1016/j.urology.2017.10.015. Epub 2017 Dec 6. PMID: 29080783.

    Article  PubMed  Google Scholar 

  47. Janoff DM, Skoog SJ. Congenital scrotal agenesis: description of a rare anomaly and management strategies. J Urol. 2005;173(2):589–91. https://doi.org/10.1097/01.ju.0000151136.56430.53. PMID: 15643265.

    Article  PubMed  Google Scholar 

  48. Shukla RM, Mandal KC, Roy D, Patra MP, Mukhopadhyay B. Scrotoschisis: an extremely rare congenital anomaly. J Indian Assoc Pediatr Surg. 2012;17(4):176–7. https://doi.org/10.4103/0971-9261.102342. PMID: 23243373; PMCID: PMC3518999.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Mahfouz M. Scrotoschisis: a rare congenital urologic anomaly. J Pediatr Surg Case Rep. 2018;32:90–2. https://doi.org/10.1016/j.epsc.2018.02.013. ISSN 2213-5766.

    Article  Google Scholar 

  50. Fahmy MAB. Testis. In: Rare congenital genitourinary anomalies. Berlin: Springer; 2015. https://doi.org/10.1007/978-3-662-43680-6_5.

    Chapter  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

AL-Mamari, S.A. (2023). Anatomy of the Scrotum and Testicles. In: Urogenital Trauma: A Practical Guide. Springer, Singapore. https://doi.org/10.1007/978-981-99-6171-9_42

Download citation

  • DOI: https://doi.org/10.1007/978-981-99-6171-9_42

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-6170-2

  • Online ISBN: 978-981-99-6171-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics