Abstract
Bifid scrotum is a rare congenital anomaly affecting the midline of the scrotum in a different spectra, in severe form the two scrotal sacs are widely separated with a laid opened urethra in the form of proximal hypospadias and the scrotal raphe is not detectable. Minor forms had a splitted or wide scrotal raphe and partial bifid scrotum may be seen at the proximal scrotal end or distally at the base of the scrotum, the later cases will give the look of scrotal dimple, which is a normal findings in some animals. Bifid scrota are usually associated with penoscrotal hypospadias, hypogonadism and androgen insensitivity syndrome, but it could be an isolated genital anomaly in association with rare somatic syndromes and maldevelopment. Bifid scrotum should be discussed along other related anomalies of the median raphae, perineal groove, accessory scrotum, scrotal transposition and diphallia. Embryologically the bifid scrotum is due to the lack of ventral growth of the caudal mesenchyme which causes failure of the urogenital folds to close over the cloacal membrane in the ventral midline. Selection of surgery to reconstruct scrotum is based on the severity of scrotal cleft and commonly done along hypospadias repair. Bifid scrotum reported recently as an indication for the severity of the associated hypospadias, and could determine the suitable type for its repair.
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Abbreviations
- SSS:
-
Separation of the Scrotal Sac
- AIS:
-
Androgen Insensitivity Syndrome
- MR:
-
Median Raphae
- VEG:
-
Virilization of the external genitalia
- SMR:
-
Split Median Raphe
References
Schoenwolf GC, Bieyl SB, Brauer PR, Francis-West P. Larsen’s Human Embryology. 4th ed. Philadelphia, PA: Churchill Livingstone; 2008.
Tuchmann-Duplessis J, Herbert QS, Haegel S, Pierre T. Organo-genese. 2nd ed. Paris: Masson, 1970.
Moore KL, Persaud TVN, Torchia MG. The developing human. 10th ed. Philadelphia: Elsevier; 2013.
Arey LB. Developmental anatomy: a textbook and laboratory manual of embryology. 7th ed. Philadelphia: WB Saunders; 1966. p. 308–12.
Neff JH. Congenital canals and cysts of the genito-perineal raphe. Am J Surg. 1936;31:308. https://doi.org/10.1016/S0002-9610(36)90493-2.
Clifford GR, Krieger JN, Rein MF. Gonococcal infection of the median penile raphe. J Urol. 1983;VL(130):138–9. https://doi.org/10.1016/S0022-5347(17)50999-4.
Prader A. Genital findings in the female pseudo-hermaphroditism of the congenital adrenogenital syndrome; morphology, frequency, development and heredity of the different genital forms. Helv Paediatr Acta. 1954;9(3):231–48.
Sekaran P, Shawis R. Perineal groove: a rare congenital abnormality of failure of fusion of the perineal raphe and discussion of its embryological origin. Clin Anat. 2009;22:823–5. https://doi.org/10.1002/ca.20855.
Chatterjee SK, Chatterjee US, Chatterjee U. Perineal groove with penoscrotal hypospadias. Pediatr Surg Int. 2003;19:554–6.
Sekaran P, Shawis R. Perineal groove: A rare congenital abnormality of failure of fusion of the perineal raphe and discussion of its embryological origin. Clin Anat (New York, NY). 2009;22(7):823–5.
McCann J, Voris J, Simon M, Wells R. Perianal findings in prepubertal children selected for nonabuse: a descriptive study. Child Abuse Negl. 1989;13(2):179–93. https://doi.org/10.1016/0145-2134(89)90005-7.
Gangopadhyayl AN, Biswasl SK, Khanna S. Exstrophy of the uroreetal septum-report of two cases and embryological review. Pediatric Surg Int. 1992;7:311–3.
Valerio E, Cutrone M. Split median raphe: case series and brief literature review. Pediatr Dermatol. 2014;31:e136–9. https://doi.org/10.1111/pde.12417.
Rocha EF, Francelino R, Santos NA, et al. Prevalence of scrotum bipartition in sheep in the Paraiba backwoods Brazil. Anim Reprod. 2018;15:1199–204.
Rodrigues RTGA et al. Influence of scrotal bipartition on spermatogenesis yield and sertoli cell efficiency in sheep. Pesq Vet Bras. 2016;36(4):258–62.
Ger R. The scrotal dimple in testicular torsion. Surgery. 1969;66:907–8.. PMID: 5356920.
Çiftdemir NA et al. Accessory scrotum with bifid scrotum and hypospadias. Turkish J Pediatr Dis. 2013;(1):38–40.
Chiang G, Cendron M. Chapter 42—disorders of the penis and scrotum. In: Pediatric urology, 2nd edn. Elsevier; 2010. pp. 544–62. https://doi.org/10.1016/B978-1-4160-3204-5.00042-6.
Avellán L. Morphology of hypospadias. Scand J Plast Surg. 1980;14:239–47.
Arnaud A, Cyril Ferdynus C, Harper L. Can separation of the scrotal sac in proximal hypospadias reliably predict the need for urethral plate transection? J Pediatr Urol. 2016;12:121.e1e121.e5.
Gyftopoulos K, Wolffenbuttel KP, Nijman RJ. Clinical and embryologic aspects of penile duplication and associated anomalies. Urology. 2002;60:675.
Perovic S, Vukadinovic V. Penoscrotal transposition with hypospadias: 1-stage repair. J Urol. 1992;148:1510–3.
Ekenze SO, Adiri CO, Igwilo IO, Onumaegbu OO. Virilized external genitalia in young girls: clinical characteristics and management challenges in a low-resource setting. J Pediatr Adolesc Gynecol. 2014;27(1):6–9. https://doi.org/10.1016/j.jpag.2013.07.004.
Kaufman FR, Costin G, Goebelsmann U, Stanczyk Z, Zachmann M. Male pseudohermaphroditism due to 17,20-desmolase deficiency. J Clin Endocrinol Metab. 1983;57:32–6.
Cunningham DM, Ragsdale JL. Genital anomalies of an xXx y male subject. J Urol. 1972;(107):872–4.
Fraccaro M, Kaijser K, Lindsten J. A child with 49 chromosomes. Lancet. 1960;2:899.
Vargas RA, Maegawa GH, Taucher SC, Leite JC, Sanz P, et al. Beare-Stevenson syndrome: two South American patients with FGFR2 analysis. Am J Med Genet A. 2003;121A:41–6.
Lees MM, Winter RM, Malcolm S, et al. Popliteal pterygium syndrome: a clinical study of three families and report of linkage to the Van der Woude syndrome locus on 1q32. J Med Genet. 1999;36:888–92.
Green JS, Parfrey PS, Harnett JD, et al. The cardinal manifestations of Bardet-Biedl syndrome, a form of Laurence-Moon-Biedl syndrome. N Engl J Med. 1989;321:1002–9.
Defoor W, Wacksman J. Results of single staged hypospadias surgery to repair penoscrotal hypospadias with bifid scrotum or penoscrotal transposition. J Urol. 2003;170:1585–8.
Mokhless I, Youssif M, Eltayeb M, et al. Z-plasty for sculpturing of the bifid scrotum in severe hypospadias associated with penoscrotal transposition. J Pediatr Urol. 2011;7(3):305–9.
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Fahmy, M.A.B. (2022). Bifid Scrotum. In: Fahmy, M.A.B. (eds) Normal and Abnormal Scrotum. Springer, Cham. https://doi.org/10.1007/978-3-030-83305-3_14
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DOI: https://doi.org/10.1007/978-3-030-83305-3_14
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