Skip to main content
SpringerLink
Log in

The Use of Immunopotentiators in Aquaculture

  • Chapter
  • First Online:
Aquaculture Science and Engineering

  • 743 Accesses

Abstract

Immunopotentiator can activate the immune system, improve the specific and nonspecific immunity of aquatic animals, thereby enhancing the ability to resist infection by pathogenic microorganisms. In recent years, aquaculture diseases have occurred frequently. In order to maintain the health of fish and other aquatic animals, and increase the benefits of aquaculture production, adding growth-promoting immunopotentiator in feed can improve the immune response, promote growth, and reduce the occurrence of diseases. As a substance that effectively controls the occurrence of aquatic animal diseases, it has been widely used in aquaculture. Through its regulation and improvement, the immunity and growth performance of aquatic animals can not only reduce environmental pollution but also ensure human food safety. This article reviewed the research progress of some commonly used immunopotentiator and its biological activities, hoping to provide a valuable reference.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Ahmad MH, Abdel-Tawwab M (2011) The use of caraway seed meal as a feed additive in fish diets: growth performance, feed utilization, and whole-body composition of Nile tilapia, Oreochromis niloticus (L.) fingerlings. Aquaculture 314:110–114

    Article  CAS  Google Scholar 

  • Ahmad MH, El Mesallamy AMD, Samir F, Zahran F (2011) Effect of cinnamon (Cinnamomum zeylanicum) on growth performance, feed utilization, whole-body composition, and resistance to Aeromonas hydrophilain Nile tilapia. J Appl Aquac 23:289–298

    Article  Google Scholar 

  • Ai Q, Mai K, Zhang L, Tan B, Zhang W, Xu W, Li H (2007) Effects of dietary beta-1, 3 glucan on innate immune response of large yellow croaker, Pseudosciaena crocea. Fish Shellfish Immunol 22:394–402

    Article  CAS  PubMed  Google Scholar 

  • Akbary P, Aminikhoei Z (2017) Effect of water-soluble polysaccharide extract from the green alga Ulva rigida on growth performance, antioxidant enzyme activity, and immune stimulation of grey mullet Mugil cephalus. J Appl Phycol 30:1345–1353

    Article  CAS  Google Scholar 

  • Alishahi M, Ranjbar MM, Ghorbanpour M, Peyghan R, Mesbah M, M. Razi jalali. (2010) Effects of dietary Aloe vera on some specific and nonspecific immunity in the common carp (Cyprinus carpio). Int J Vet Res 3:189–195

    Google Scholar 

  • Ardó L, Yin G, Xu P, Váradi L, Szigeti G, Jeney Z, Jeney G (2008) Chinese herbs (Astragalus membranaceus and Lonicera japonica) and boron enhance the non-specific immune response of Nile tilapia (Oreochromis niloticus) and resistance against Aeromonas hydrophila. Aquaculture 275:26–33

    Article  CAS  Google Scholar 

  • Baba E, Acar Ãœ, ÖntaÅŸ C, Kesbiç OS, Yılmaz S (2016) Evaluation of Citrus Limon peels essential oil on growth performance, immune response of Mozambique tilapia Oreochromis mossambicus challenged with Edwardsiella tarda. Aquaculture 465:13–18

    Article  CAS  Google Scholar 

  • Bai N, Zhang W, Mai K, Wang X, Xu W, Ma H (2010) Effects of discontinuous administration of β-glucan and glycyrrhizin on the growth and immunity of white shrimp Litopenaeus vannamei. Aquaculture 306:218–224

    Article  CAS  Google Scholar 

  • Cao JM, Wu CY, Huang YH, Wang GX, Zhao HX, Mo WY, Qi F, Fu LL (2015) Effects of dietary β-glucan on immunity and Antioxidation indices in Japanese seabass Lateolabrax japonicus. Fish Sci 34:1–7

    Google Scholar 

  • Chai XQ, Leng XJ, Li XQ, Shan LL, Song HB (2012) Effect of antibacterial peptide on growth and serum non-specific immunity of Litopenaeus vannamei. Freshwater Fisheries 42:59–62

    Google Scholar 

  • Chatzifotis S, Kokou F, Ampatzis K, Papadakis IE, Divanach P, Dermon CR (2008) Effects of dietary caffeine on growth, body composition, somatic indexes, and cerebral distribution of acetyl-cholinesterase and nitric oxide synthase in gilthead sea bream (Sparus aurata), reared in winter temperature. Aquacult Nutr 14:405–415

    Article  CAS  Google Scholar 

  • Chen B, Huang YH, Zhao HX, Chen XY, Wang GX, Sun YP (2015) Effects of antibacterial peptides of Musca domestica on anti-white spot syndrome virus capacity in Litopenaeus vannamei. Guangdong Agric Sci 42:116–120

    Google Scholar 

  • Chen CL (2016) Analysis of the effect of different doses of probiotics on disease resistance of tilapia. Scientific Fish Farming

    Google Scholar 

  • Chen QQ, Liu WB, Zhou M, Dai YJ, Xu C, Tian HY, Xu WN (2016) Effects of berberine on the growth and immune performance in response to ammonia stress and high-fat dietary in blunt snout bream Megalobrama amblycephala. Fish Shellfish Immunol 55:165–172

    Article  CAS  PubMed  Google Scholar 

  • Chen YZ, Guan XY, Xiao QW, Wang SW, Liu JG (2014) The function of Chinese herbal medicine in the reconstruction of periodontal tissue during orthodontic tooth movement. Chin J Tissue Eng Res 18:7477–7481

    Google Scholar 

  • Chi SY, Zhou QC, Zhou JB, Yang QH, Dong XH (2006) Effects of dietaryβ-glucan on growth performance and disease resistance of juvenile hybrid tilapia. J Fishery Sci China 2006:767–774

    Google Scholar 

  • Chiou MJ, Chen LK, Peng KC, Pan CY, Lin TL, Chen JY (2009) Stable expression in a Chinese hamster ovary (CHO) cell line of bioactive recombinant chelonianin, which plays an important role in protecting fish against pathogenic infection. Dev Comp Immunol 33:117–126

    Article  CAS  PubMed  Google Scholar 

  • Dhayanithi NB, Kumar TT, Arockiaraj J, Balasundaram C, Harikrishnan R (2015) Dietary supplementation of Avicennia marina extract on immune protection and disease resistance in Amphiprion sebae against vibrio alginolyticus. Fish Shellfish Immunol 45:52–58

    Article  PubMed  Google Scholar 

  • Do Huu H, Sang HM, Thanh Thuy NT (2016) Dietary beta-glucan improved growth performance, vibrio counts, haematological parameters and stress resistance of pompano fish, Trachinotus ovatus Linnaeus, 1758. Fish Shellfish Immunol 54:402–410

    Article  PubMed  CAS  Google Scholar 

  • Dong XQ, Qu GJ, Chen YK, Zhang DM (2015a) Research progress of antibacterial peptides in aquaculture. Heilongjiang Anim Sci Veter Med 12:62–64

    Google Scholar 

  • Dong XQ, Zhang DM, Chen YK, Qu GJ, Yang YY (2017) Effects of antimicrobial peptides on muscle A Mino acid and fatty acid composition in common carp (CyPrinus Carpio). Chin J Animal Sci 53:79–84

    Google Scholar 

  • Dong XQ, Zhang DM, Chen YK, Wang QJ, Li B, Yang YY, Ju X (2015b) Effects of antibacterial peptide on growth performances, viscera index and muscle composition in common carp (Cyprinus carpio). Chin J Animal Sci 51:47–51

    Google Scholar 

  • Dong XQ, Zhang DM, Chen YK, Wang QJ, Yang YY (2015c) Effects of antimicrobial peptides (AMPs) on blood biochemical parameters, antioxidase activity, and immune function in the common carp (Cyprinus carpio). Fish Shellfish Immunol 47:429–434

    Article  CAS  PubMed  Google Scholar 

  • Francis G, Makkar HPS, Becker K (2005) Quillaja saponins—a natural growth promoter for fish. Anim Feed Sci Technol 121:147–157

    Article  CAS  Google Scholar 

  • Ge L, Liu XZ, Gao J, Wang ZM (2018) Advances on antibacterial mechanisms of antimicrobial peptides and synergistic effects with antibiotics. Chin J Antibiot 43:1474–1481

    Google Scholar 

  • Gobi N, Ramya C, Vaseeharan B, Malaikozhundan B, Vijayakumar S, Murugan K, Benelli G (2016) Oreochromis mossambicus diet supplementation with Psidium guajava leaf extracts enhance growth, immune, antioxidant response and resistance to Aeromonas hydrophila. Fish Shellfish Immunol 58:572–583

    Article  CAS  PubMed  Google Scholar 

  • Gong J, Yin F, Hou Y, Yin Y (2014) Review: Chinese herbs as alternatives to antibiotics in feed for swine and poultry production: potential and challenges in application. Can J Anim Sci 94:223–241

    Article  Google Scholar 

  • Guo YJ, Xing KZ, Chen CX, Yang YX, Zhu GX (2005) Study on some Chinese herb medicines as feed attractant on carp(Cyprinus carpio). J Tianjin Agric Coll 12:1–5

    Google Scholar 

  • Guzman-Villanueva LT, Tovar-Ramirez D, Gisbert E, Cordero H, Guardiola FA, Cuesta A, Meseguer J, Ascencio-Valle F, Esteban MA (2014) Dietary administration of beta-1,3/1,6-glucan and probiotic strain Shewanella putrefaciens, single or combined, on gilthead seabream growth, immune responses and gene expression. Fish Shellfish Immunol 39:34–41

    Article  CAS  PubMed  Google Scholar 

  • He YJ, Liu B, Xie J, Ge XP, Xu P, Lu Y, Lu FX, Lu ZX (2017) Effects of antibacterial peptide extracted from Bacillus subtilis fmbJ on the growth, physiological response and disease resistance of Megalobrama amblycephala. Israeli J Aquac 2017:66

    Google Scholar 

  • Hoseinifar SH, Zoheiri F, Lazado CC (2016) Dietary phytoimmunostimulant Persian hogweed (Heracleum persicum) has more remarkable impacts on skin mucus than on serum in common carp (Cyprinus carpio). Fish Shellfish Immunol 59:77–82

    Article  CAS  PubMed  Google Scholar 

  • Hsieh T-J, Wang J-C, Hu C-Y, Li C-T, Kuo C-M, Hsieh S-L (2008) Effects of Rutin from Toona sinensis on the immune and physiological responses of white shrimp (Litopenaeus vannamei) under vibrio alginolyticus challenge. Fish Shellfish Immunol 25:581–588

    Article  CAS  PubMed  Google Scholar 

  • Hu SK, Wang B, Liao XZ, Sun CB, Liu YS, Qu P (2018) Effect of microbial antimicrobial peptides on disease resistance and immune indices of Litopenaeus vannamei. J Trop Biol 9:281–286

    Google Scholar 

  • Hu ZZ, Yang JF, Tan ZJ, Hao JL (2003) Effects of curcumin on the growth and intestinal enzyme activity of grass carp. Cereal Feed Industr 2003:29–30

    Google Scholar 

  • Huang CH, Li B, Wang DD, Liu M, Zhu FM, Qiao SY (2009) The effect of antibacterial peptides on the growth performance of tilapia juveniles. Chin J Animal Sci 45:53–56

    Google Scholar 

  • Huang CH, Li CH, Zhang DD (2011) Comparative study on the effects of antibacterial peptides and common antibiotics on the growth performance of tilapia. Chin J Animal Sci 47:52–55

    CAS  Google Scholar 

  • Jia T, Wang DD, Li B (2015) Effects of Cecropins on the growth performance of common carp cultured in cages. Henan Fisher 2015:26–28

    Google Scholar 

  • Jiang C, Wang P, Li M, Liu S, Zhang S (2016) Dietary beta-glucan enhances the contents of complement component 3 and factor B in eggs of zebrafish. Dev Comp Immunol 65:107–113

    Article  CAS  PubMed  Google Scholar 

  • Jiang L, Zheng SM (2006) Pharmacodynamic studies on Chinese nutgall against Bacter ial septicemia of carp (Cyprinus carpio). Chin Agric Sci Bull 22:460–464

    Google Scholar 

  • Jiang S, Wang BJ, Liu M, Jiang KY, Gong K, Wang L (2011) Effects of recombinant antimicrobial peptides on growth and immunity in tilapia. J Fishery Sci China 18:1308–1314

    Article  CAS  Google Scholar 

  • Kong XF, Hu YL, Yin YL, Wu GY, Rui R, Wang DY, Yang CB (2006) Chinese herbal ingredients are effective immune stimulators for chickens infected with the Newcastle disease virus. Poult Sci 85:2169–2175

    Article  CAS  PubMed  Google Scholar 

  • Kuhlwein H, Emery MJ, Rawling MD, Harper GM, Merrifield DL, Davies SJ (2013) Effects of a dietary beta-(1,3)(1,6)-D-glucan supplementation on intestinal microbial communities and intestinal ultrastructure of mirror carp (Cyprinus carpio L.). J Appl Microbiol 115:1091–1106

    Article  CAS  PubMed  Google Scholar 

  • Li J, Wu ZB, Zhang Z, Zha JW, Qu SY, Qi XZ, Wang GX, Ling F (2019) Effects of potential probiotic bacillus velezensis K2 on growth, immunity and resistance to Vibrio harveyi infection of hybrid grouper (Epinephelus lanceolatusmale symbol x E. fuscoguttatusfemale symbol). Fish Shellfish Immunol 93:1047–1055

    Article  CAS  PubMed  Google Scholar 

  • Li NS, Leng XJ, Li XQ, Liu B, Chai XQ, Li ZM, Zhen XM (2014) The effects of Chlorogenic acid on the growth, non-specific immune index and the meat quality of juvenile grass Capp(Ctenopharyngodon Idellus). Acta Hydrobiol Sin 38:619–626

    CAS  Google Scholar 

  • Li YJ, Ye JY, Zhang YX, Liu W (2015) Advances on antimicrobial peptides fish from derive. Fish Sci 34:464–468

    CAS  Google Scholar 

  • Lin SM, Jiang Y, Chen YJ, Luo L, Doolgindachbaporn S, Yuangsoi B (2017) Effects of Astragalus polysaccharides (APS) and chitooligosaccharides (COS) on growth, immune response and disease resistance of juvenile largemouth bass. Micropterus salmoides Fish Shellfish Immunol 70:40–47

    Article  CAS  PubMed  Google Scholar 

  • Lin X, Chen W, Lin S, Luo L (2015) Effects of dietary cecropin on growth, non-specific immunity and disease resistance of tilapia (Oreochromis niloticus × O. aureus). Aquacult Res 46:2999–3007

    Article  CAS  Google Scholar 

  • Lin X, Mao SH, Yang Y, Lin SM, Luo L (2013) Effects of antimicrobial peptides supplementation on growth, non-specific immunity and disease resistance of Koi (Cyprinus carpio koi). Chin J Anim Nutri 25:1860–1865

    CAS  Google Scholar 

  • Liu B, Xie J, Ge X, Xu P, Wang A, He Y, Zhou Q, Pan L, Chen R (2010) Effects of anthraquinone extract from Rheum officinale bail on the growth performance and physiological responses of Macrobrachium rosenbergii under high temperature stress. Fish Shellfish Immunol 29:49–57

    Article  PubMed  CAS  Google Scholar 

  • Liu LH, Zheng SX, Tan B, Dong AH, Huang LL, Chen LQ (2005) Effect of β-glucan on growth performance and non-specific immunity of Litopenaeus vannamei under different feed formulations and cost analysis. Feed Industr 26:26–30

    Google Scholar 

  • Liu LZ, Tian XL, Wang MH, Li HD, Li L, Dong SL, Feng JH (2018) Effect of additive patterns of Omnibiotics on the growth performance, non-specific immunity and disease resistance of Litopenaeus vannamei. Periodical of Ocean University of China 48:023–031

    Google Scholar 

  • Liu W-C, Zhou S-H, Balasubramanian B, Zeng F-Y, Sun C-B, Pang H-Y (2020) Dietary seaweed (Enteromorpha) polysaccharides improves growth performance involved in regulation of immune responses, intestinal morphology and microbial community in banana shrimp Fenneropenaeus merguiensis. Fish Shellfish Immunol 104:202–212

    Article  CAS  PubMed  Google Scholar 

  • Luan CY, Guo WP, Deng JQ, Zhao J, Quan CS (2017) Strain identification of a compound microecological liquid preparation for aquaculture. Light Industry Sci Technol 33:6–8

    Google Scholar 

  • Ma AM, Yan MC, Chang WS, Xie QL, Chen SB, Shan LZ (2009) Effects of Chinese herbs on the growth and immune function in Sciaenops ocellatus. Mar Sci 33:96–102

    Google Scholar 

  • Martínez JGS, Castro JLR, Sauceda MV, Castañeda RP, Martínez ZB, González FB (2017) Effect of β-glucan dietary levels on immune response and hematology of channel catfish Ictalurus punctatus juveniles. Lat Am J Aquat Res 45:690–698

    Google Scholar 

  • Midhun SJ, Arun D, Neethu S, Vysakh A, Radhakrishnan EK, Jyothis M (2019) Administration of probiotic Paenibacillus polymyxa HGA4C induces morphometric, enzymatic and gene expression changes in Oreochromis niloticus. Aquaculture 508:52–59

    Article  CAS  Google Scholar 

  • Miest JJ, Arndt C, Adamek M, Steinhagen D, Reusch TB (2016) Dietary beta-glucan (MacroGard(R)) enhances survival of first feeding turbot (Scophthalmus maximus) larvae by altering immunity, metabolism and microbiota. Fish Shellfish Immunol 48:94–104

    Article  CAS  PubMed  Google Scholar 

  • Pan CY, Huang TC, Wang YD, Yeh YC, Hui CF, Chen JY (2012) Oral administration of recombinant epinecidin-1 protected grouper (Epinephelus coioides) and zebrafish (Danio rerio) from Vibrio vulnificus infection and enhanced immune-related gene expressions. Fish Shellfish Immunol 32:947–957

    Article  CAS  PubMed  Google Scholar 

  • Peng XY, Shen MH (2010) Effects of aqueous extract of Taraxacum Mongol icum hand-maz z. on growth performance, muscle composition, digestive enzyme and immune system of Carassius Auratus Linn. China. Animal Husb Veter Med 37:13–17

    Google Scholar 

  • Qin ZB, Liang JZ, Long S, Niu ZW, He CJ, Huang J (2016) Effects of antibacterial peptides on growth performance and body composition of Penaeus vannamei. J Southern Agric 47:674–678

    CAS  Google Scholar 

  • Rattanachaikunsopon P, Phumkhachorn P (2010) Use of asiatic pennywort Centella asiatica aqueous extract as a bath treatment to control columnaris in Nile tilapia. J Aquat Anim Health 22:14–20

    Article  CAS  PubMed  Google Scholar 

  • Ringø E, Myklebust R, Mayhew TM, Olsen RE (2007) Bacterial translocation and pathogenesis in the digestive tract of larvae and fry. Aquaculture 268:251–264

    Article  Google Scholar 

  • Sanchez J, Rabago J, Vazquez M, Perez R, Blanco Z, Benavides F (2017) Effect of β glucan dietary levels on immune response and hematology of channel catfish Ictalurus punctatus juveniles. Lat Am J Aquat Res 45:690–698

    Article  Google Scholar 

  • Schmitt P, Wacyk J, Morales-Lange B, Rojas V, Guzman F, Dixon B, Mercado L (2015) Immunomodulatory effect of cathelicidins in response to a beta-glucan in intestinal epithelial cells from rainbow trout. Dev Comp Immunol 51:160–169

    Article  CAS  PubMed  Google Scholar 

  • Serra CR, Almeida EM, Guerreiro I, Santos R, Merrifield DL, Tavares F, Oliva-Teles A, Enes P (2019) Selection of carbohydrate-active probiotics from the gut of carnivorous fish fed plant-based diets. Sci Rep 9:6384

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Shalaby AM, Khattab YA, Rahman AMA (2006) Effects of garlic (Allium sativum) and chloramphenicol on growth performance, physiological parameters and survival of Nile Tilspia. J Venom Anim Toxins incl Trop Dis 12:172–201

    Article  Google Scholar 

  • Shang BJ, Zuo ZH, Dou CM, Li WY, Sun JS (2018) Analysis of the characteristics of Litopenaeus vannamei intestinal microflora after being fed with two probiotics using high-throughput sequencing method. J Fish China 42:1967–1976

    Google Scholar 

  • Shao L, Li J, Yue L, Wu KN, Du HM, Wang L (2018) Effects of Bacillus subtilis and Rhodopseudomonas palustris on the immune function of crucian carp and the antibacterial activity of their metabolites. Heilongjiang Anim Sci Veter Med 2018:176–178

    Google Scholar 

  • Song WH, Hu ZY, Fu LJ, Zhang T, Li H, Yao FX, Zhang J (2011) The effects of Hypercin, Chlorogenic acid and Scleroglucan on growth performance and immune function in juvenile grass carp Ctenopharyngodon idellus. Chin J Fisher 24:21–25

    CAS  Google Scholar 

  • Su YL, Chen G, Chen LS, Li JZ, Wang G, He JY, Zhan TY, Li YW, Yan MT, Huang YH, Qin QW, Dan XM, Sun HY (2019) Effects of antimicrobial peptides on serum biochemical parameters, antioxidant activity and non-specific immune responses in Epinephelus coioides. Fish Shellfish Immunol 86:1081–1087

    Article  CAS  PubMed  Google Scholar 

  • Sun Z, Tan X, Ye H, Zou C, Ye C, Wang A (2018) Effects of dietary Panax notoginseng extract on growth performance, fish composition, immune responses, intestinal histology and immune related genes expression of hybrid grouper (Epinephelus lanceolatus male symbol x Epinephelus fuscoguttatus female symbol) fed high lipid diets. Fish Shellfish Immunol 73:234–244

    Article  CAS  PubMed  Google Scholar 

  • Talib A, Onn KK, Chowdury MA, Din WMW, Yahya K (2016) The beneficial effects of multispecies bacillus as probiotics in enhancing culture performance for mud crab Scylla paramamosain larval culture. Aquac Int 25:849–866

    Article  Google Scholar 

  • Tan CG, Leng XJ, Li XQ, Su XG, Liu B, Chai SQ (2013) Effects of polysaccharides, oligosaccharides and protease on growth, digestive enzyme activities and serum nonspecific immunity of white shrimp (Litopenaeus vannamei). J Shanghai Ocean Univ 22:93–99

    CAS  Google Scholar 

  • Tan J, Deng FY, Cao YJ, Yao YZ, Ma C (2015) Effects of Chinese herbal compound in feed on growth, muscle composition and immune-related enzyme activities of juvenile grass carp (Ctenopharyngodon idellus). Guangdong Agric Sci 42:109–113

    Google Scholar 

  • Tan X, Sun Z, Chen S, Chen S, Huang Z, Zhou C, Zou C, Liu Q, Ye H, Lin H, Ye C, Wang A (2017) Effects of dietary dandelion extracts on growth performance, body composition, plasma biochemical parameters, immune responses and disease resistance of juvenile golden pompano Trachinotus ovatus. Fish Shellfish Immunol 66:198–206

    Article  CAS  PubMed  Google Scholar 

  • Tang J, Cai J, Liu R, Wang J, Lu Y, Wu Z, Jian J (2014) Immunostimulatory effects of artificial feed supplemented with a Chinese herbal mixture on Oreochromis niloticus against Aeromonas hydrophila. Fish Shellfish Immunol 39:401–406

    Article  CAS  PubMed  Google Scholar 

  • Ting CH, Chen YC, Chen JY (2018) Nile tilapia fry fed on antimicrobial peptide Epinecidin-1-expressing Artemia cyst exhibit enhanced immunity against acute bacterial infection. Fish Shellfish Immunol 81:37–48

    Article  CAS  PubMed  Google Scholar 

  • Ushakova NA, Nekrasov RV, Pravdin IV, Sverchkova NV, Kolomiyets EI, Pavlov DS (2015) Mechanisms of the effects of probiotics on symbiotic digestion. Biol Bull 42:394–400

    Article  Google Scholar 

  • Wang DD, Li B (2012) Effect of Cecropin antimicrobial peptide on the production performance of tilapia juvenile fish. Animal Agric 2012:57–58

    Google Scholar 

  • Wang GX, Wang FJ, Yuan JL, Shen HY, Z. W. and L. Li. (2007) Activity of Sanguinarine from Macleaya cordata to Dact ylogyrus and six pathogenic bacteria in aquaculture. Acta Botan Boreali-Occiden Sin 2007:1650–1655

    Google Scholar 

  • Wang HL, Zhang DS, Du G, Sun WR, Zhao XL, Zhou QL, Xie J (2009) Study on the Bacteriostasis test of Eucommia leaf extract on crucian carp hemorrhagic pathogen. Feed Industry 30:28–30

    Google Scholar 

  • Wang JB, Wu TX (2007) Study on the effect of curcumin in the feed of large yellow croaker. Jf Hydroecol 27:105–106

    Google Scholar 

  • Wang QF, Yang Y, Zhou ZM, Zha CX (2016a) Effects of different probiotics on the production performance of grass carp. Animals Breed Feed 2016:44–46

    Google Scholar 

  • Wang QK, Zhao HY, Lv ZM, Chen CX, Xing KZ (2011a) Effects of dietary Angelica sinensis polysaccharide on nonspecific immunity of Epinephelus malabaricus. J Anhui Agric Sci 39:13857–13860

    CAS  Google Scholar 

  • Wang YD, Kung CW, Chen JY (2010) Antiviral activity by fish antimicrobial peptides of epinecidin-1 and hepcidin 1-5 against nervous necrosis virus in medaka. Peptides 31:1026–1033

    Article  PubMed  CAS  Google Scholar 

  • Wang YH, Wang YY, Mai KS, Xu W, Zhang YJ, Zhou HH, Gong Y, Ai QH (2016b) Effect of dietary curcumin on growth performance body, composition and serum antioxidant enzyme activity in juvenile turbot. J Fish China 40:1299–1308

    Google Scholar 

  • Wang YJ, He YJ, Xie J, Liu B, Ge XP, Zhou QL, Xu L, Pan LK, Chen RL (2011b) The effect of antibacterial peptides on the growth, immunity and antioxidant capacity of river crab. Jiangsu Agric Sci 39:340–343

    Google Scholar 

  • Wang ZR, Qiao SY, Li B, Ruan JM, Wei LL, Yang ZQ (2014) Cecropin: effects on growth performance, non-specific immunity and disease resistance of triploid Crucian Carp. Chin J Anim Nutri 26:1856–1863

    CAS  Google Scholar 

  • Wen AX, Shu H, Xiao Y (2010) Effects of Chlorogenic acid on performance and antioxidant capability of Trionyx sinensis. Chin J Anim Nutri 22:729–733

    CAS  Google Scholar 

  • Wen X, Gao FX (2013) Research Progress of antimicrobial Peptides' bactericidal mechanism. China Feed 24:8–11

    Google Scholar 

  • Wu ML, Chen BJ, Liu J, Chen HY, Peng H (2015) Effects of oral administration of antimicrobial peptide Scygonadin on immune and antioxidant indexes of black sea bream. Biotech World 2015:4–7

    Google Scholar 

  • Wu YS, Chen YY, Ueng PS, Nan FH (2016) Effects of medicinal herbs "Plantago asiatica", "Houttuynia cordata" and "Mentha haplocalyx" on non-specific immune responses of cobia (Rachycentron canadum). Fish Shellfish Immunol 58:406–414

    Article  PubMed  Google Scholar 

  • Xia Y, Yu DG, Yu EM, Xie J, Wang GJ, Wang HY, Gong WB (2012) Effects of dietary antimicrobial peptide and Bacillus subtilis on growth performance and non-specific immunity of Lateolabrax japonicus. Freshwater Fisheries 42:52–57

    Google Scholar 

  • Xue LG, Ma P, Shang H, He XY, Chen XM, Liu GX, Chen T, Zhang W (2017) Research advances on antimicrobial peptides of fish and amphibians. Biotechnol Bull 33:61–66

    Google Scholar 

  • Yang FG, Zhou HQ, Huang XH (2005) Effect of beta-glucans on growth and non-specific immune response of Litopenaeus vannamei. J Shanghai Ocean Univ 14:3263–3269

    Google Scholar 

  • Yeh RY, Shiu YL, Shei SC, Cheng SC, Huang SY, Lin JC, Liu CH (2009) Evaluation of the antibacterial activity of leaf and twig extracts of stout camphor tree, Cinnamomum kanehirae, and the effects on immunity and disease resistance of white shrimp. Litopenaeus vannamei Fish Shellfish Immunol 27:26–32

    Article  PubMed  Google Scholar 

  • Yu PF, Zhao LJ, Dong LY, Fang M, Song YS, Wang JB (2016) Antimicrobial activities of the extracts from Curcuma longa on pathogenic bacteria in aquatic animals. J Anhui Agric Sci 44:148–150

    Google Scholar 

  • Zhai SW, Li J, Chen XP, Lu P, Guo QX (2015) Effect of surfactant in feed on physiological and biochemical indexes of tilapia liver and pancreas. Feed Res 46:48–54

    Google Scholar 

  • Zhang C, Wen AX (2012) Different of Chiorogenic acid doses on growth performance, non-specific immunity and antioxidant functions of Cyprinus carpio var. Jian J Sichuan Agric Univ 30:92–97

    CAS  Google Scholar 

  • Zhang LL, Zeng H, Zhang JM, Ai QH, Mai KS (2008) A study on feeding attraction activity of Chinese herbal medicine for Japanese sea bass Latoeolabrax japonicus C. Progress Fish Sci 2008:101–105

    Google Scholar 

  • Zhang XY, Peng SJ, Lv YJ, Shi P, Li YL, Sun RJ (2017) Antimicrobial peptides and its application progress in aquaculture. Feed. Research 1:5–9

    Google Scholar 

  • Zhao HX, Cao JM, Wang LA, Huang YH, Lan HB, Liu SH (2010) Effects of Long-term dietary supplementation of β-1, 3-glucan on growth performance, body composition and biochemical indices of Li topenaeus vannamei. Chin J Animal Nutri 22:1464–1470

    CAS  Google Scholar 

  • Zhao SW, Shi QC, Chen XH (2016) Effect of dietary antimicrobial peptides-surfactin supplementation on parameters of intestinal health indices of genetically improved farmed Tilaria (gift, Oreochromis NIiloticus). Acta Hydrobiol Sin 40:823–829

    Google Scholar 

  • Zhou C, Lin H, Ge X, Niu J, Wang J, Wang Y, Chen L, Huang Z, Yu W, Tan X (2015) The effects of dietary soybean isoflavones on growth, innate immune responses, hepatic antioxidant abilities and disease resistance of juvenile golden pompano Trachinotus ovatus. Fish Shellfish Immunol 43:158–166

    Article  PubMed  CAS  Google Scholar 

  • Zhou X, Peng Y, Li L, He K, Huang T, Mou S, Feng M, Han B, Ye X, Li X (2016) Effects of dietary supplementations with the fibrous root of Rhizoma Coptidis and its main alkaloids on non-specific immunity and disease resistance of common carp. Vet Immunol Immunopathol 173:34–38

    Article  CAS  PubMed  Google Scholar 

  • Zhu GX, Bai DQ, Li YH, Ma J, Wu X, Ning B (2010) Study on the feeding effect of 12 kinds of Chinese herbal medicine on juvenile turbot. J Anhui Agric Sci 38:18233–18234

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Animal Science, College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, P. R. China

    Yue Zhao & Wen-Chao Liu

Authors
  1. Yue Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wen-Chao Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Wen-Chao Liu .

Editor information

Editors and Affiliations

  1. Department of Food Science and Biotechnology, Sejong University, Seoul, Korea (Republic of)

    Balamuralikrishnan Balasubramanian

  2. Department of Animal Science, Guangdong Ocean University, Zhanjiang, China

    Wen-Chao Liu

  3. Department of Zoology, St.Joseph University, Dimapur, Nagaland, India

    Govindharajan Sattanathan

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Zhao, Y., Liu, WC. (2022). The Use of Immunopotentiators in Aquaculture. In: Balasubramanian, B., Liu, WC., Sattanathan, G. (eds) Aquaculture Science and Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-19-0817-0_10

Download citation

Publish with us

Policies and ethics

Search

Navigation