Abstract
The present work evaluated the effects of LED light therapy at 640 nm on healing the navels of newborns by using animal model. Fifty-seven neonatal calves were divided into two study groups. The members of the control group had the umbilical stump immersed in a solution of 10% tincture of iodine for 60 s, which was repeated every 24 h for three consecutive days. The members of the treated group received light doses of 7.2 J that were applied to four points evenly distributed around the insertion site of umbilical stump every 24 h for three consecutive days before the umbilical stumps were immersed in the iodine solution. The time, in days from birth, at which the umbilical stump fell off for each calf was noted. After the umbilical stump fell off, the remnant wound area was measured at different times after birth. Digital photographs with a dimensional reference were used for area measurements. The results showed that phototherapy hastened the fall-off of the umbilical stump, accelerated navel healing and reduced the mortality rate in newborn calves. We can anticipate that light treatment, as an afterbirth care, could also bring benefits to human neonates.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Mester, E., Spiry, T., Szende, B., Tota, J.G.: Effect of laser rays on wound healing. Am. J. Surg. 122, 532–535 (1971)
Abergel, R.P., Lyons, R.F., Castel, J.C., Dwyer, R.M., Uitto, J.: Biostimulation of wound healing by lasers: experimental approaches in animal models and in fibroblast cultures. J. Dermatol. Surg. Oncol. 13, 127–133 (1987)
Karu, T.: Laser biostimulation: a photobiological phenomenon. J. Photochem. Photobiol. B: Biol. 3(4), 638–640 (1989)
Cury, V., Moretti, A.I.S., Assis, L., Bossini, P., Crusca, J.S., Neto, C.B., Fangel, R., Souza, H.P., Hamblin, M.R., Parizotto, N.A.: Low level laser therapy increases angiogenesis in a model of ischemic skin flap in rats mediated by VEGF, HIF-1α and MMP-2. J. Photochem. Photobiol. B: Biol. 125, 164–170 (2013)
Sousa, A.P., Paraguassú, G.M., Silveira, N.T., Souza, J., Cangussú, M.C., Santos, J.N., Pinheiro, A.L.: Laser and LED phototherapies on angiogenesis. Lasers Med. Sci. 28(3), 981–987 (2013)
Corazza, A.V., Jorge, J., Kurachi, C., Bagnato, V.S.: Photobiomodulation on the angiogenesis of skin wounds in rats using different light sources. Photomed. Laser Surg. 25(2), 102–106 (2007)
Schaffer, M., Bonel, H., Sroka, R., Schaffer, P.M., Busch, M., Reiser, M., Dühmke, E.: Effects of 780 nm diode laser irradiation on blood microcirculation: preliminary findings on time-dependent T1-weighted contrast-enhanced magnetic resonance imaging (MRI). J. Photochem. Photobiol. B: Biol. 54(1), 55–60 (2000)
G.M. Saied, R.M. Kamel, A.M. Labib, M.T. Said, A.Z. Mohamed, The diabetic foot and leg: combined He-Ne and infrared low-intensity lasers improve skin blood perfusion and prevent potential complications. A prospective study on 30 Egyptian patients. Lasers Med. Sci. 26(5), 627–632 (2011)
Souza, S.C., Munin, E., Alves, L.P., Salgado, M.A.C., Pacheco, M.T.T.: Low power laser radiation at 685 nm stimulates stem-cell proliferation rate in Dugesia tigrina during regeneration. J. Photochem. Photobiol. B: Biol. 80(3), 203–207 (2005)
Lipovsky, A., Oron, U., Gedanken, A., Lubart, R.: Low-level visible light (LLVL) irradiation promotes proliferation of mesenchymal stem cells. Lasers Med. Sci. 28(4), 1113–1117 (2013)
Hawkins, D.H., Abrahamse, H.: Time-dependent responses of wounded human skin fibroblasts following phototherapy. J. Photochem. Photobiol. B: Biol. 88(2–3), 147–155 (2007)
Albertini, R., Villaverde, A.B., Aimbire, F., Salgado, M.A.C., Bjordal, J.M., Alves, L.P., Munin, E., Costa, M.S.: Anti-inflammatory effects of low-level laser therapy (LLLT) with two different red wavelengths (660 nm and 684 nm) in carrageenan-induced rat paw edema. J. Photochem. Photobiol. B: Biol. 89(1), 50–55 (2007)
Lima, F.M., Villaverde, A.B., Albertini, R., Corrêa, J.C., Carvalho, R.L.P., Munin, E., Araújo, T., Silva, J.A., Aimbire, F.: Dual effect of low-level laser therapy (LLLT) on the acute lung inflammation induced by intestinal ischemia and reperfusion: action on anti- and pro-inflammatory cytokines. Lasers Surg. Med. 43(5), 410–420 (2011)
Lima, F.M., Villaverde, A.B., Salgado, M.A., Castro-Faria-Neto, H.C., Munin, E., Albertini, R., Aimbire, F.: Low intensity laser therapy (LILT) in vivo acts on the neutrophils recruitment and chemokines/cytokines levels in a model of acute pulmonary inflammation induced by aerosol of lipopolysaccharide from Escherichia coli in rat. J. Photochem. Photobiol. B: Biol. 101(3), 271–278 (2010)
Paraguassú, G.M., Xavier, F.C.A., Cangussu, M.C.T., Ramalho, M.J.P., Cury, P.R., Santos, J.N., Pinheiro, A.L.B., Ramalho, L.M.P.: Effect of laser phototherapy (λ660 nm) on Type I and III collagen expression during wound healing in hypothyroid rats: an immunohistochemical study in a rodent model. Photomed. Laser Surg. 32(5), 281–288 (2014)
Souza, R.C., Junqueira, J.C., Rossoni, R.D., Pereira, C.A., Munin, E., Jorge, A.O.C.: Comparison of the photodynamic fungicidal efficacy of methylene blue, toluidine blue, malachite green and low-power laser irradiation alone against Candida albicans. Lasers Med. Sci. 25(3), 385–389 (2010)
Lee, S.Y.C., Seong, I.-W., Kim, J.-S., Cheon, K.-A., Gu, S.H., Kim, H.H., Park, K.H.: Enhancement of cutaneous immune response to bacterial infection after low-level light therapy with 1072 nm infrared light: a preliminary study. J. Photochem. Photobiol. B: Biol. 105 3 (2), 175–182 (2011)
Hawkins, D., Houreld, N., Abrahamse, H.: Low level laser therapy (LLLT) as an effective therapeutic modality for delayed wound healing. Ann. N.Y. Acad. Sci. 1056, 486–493 (2005)
Dall Agnol, M.A., Nicolau, R.A., Lima, C.J., Munin, E.: Comparative analysis of coherent light action (laser) versus non-coherent light (light-emitting diode) for tissue repair in diabetic rats. Lasers Med. Sci. 24(6), 909–916 (2009)
Fiorio, F.B., Silveira Jr., L., Munin, E., de Lima, C.J., Fernandes, K.P., Mesquita-Ferrari, R.A., Carvalho, P.T.C., Lopes-Martins, R.A.B., Aimbire, F., Carvalho, R.A.: Effect of incoherent LED radiation on third-degree burning wounds in rats. J. Cosmet. Laser Therapy 13(6), 315–322 (2011)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
de Souza Faria, A.L.B., Conrado, L.A.L., Vanzela, L.S., Villaverde, A.B., Munin, E. (2019). Phototherapy Hastens the Umbilical Cord Stump Fall Off in Calves. In: Costa-Felix, R., Machado, J., Alvarenga, A. (eds) XXVI Brazilian Congress on Biomedical Engineering. IFMBE Proceedings, vol 70/2. Springer, Singapore. https://doi.org/10.1007/978-981-13-2517-5_133
Download citation
DOI: https://doi.org/10.1007/978-981-13-2517-5_133
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-13-2516-8
Online ISBN: 978-981-13-2517-5
eBook Packages: EngineeringEngineering (R0)