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Subclassification of Hyperactive Children on the Basis of Minor Physical Anomalies and Plasma Dopamine-Beta-Hydroxylase Activity: An Attempted Replication

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The Psychobiology of Childhood

Abstract

It is generally accepted that the hyperactive reaction of childhood (Attention Deficit Disorder with Hyperactivity in DSM-III) probably represents several discrete disorders which, though similar in manifest symptomatology, differ with regard to etiological antecedents. Attempts to subclassify hyperkinetic children have been few.

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References

  • Berg C, Hart D, Quinn P, Rapoport J: Newborn minor physical anomalies and prediction of infant behavior. J Aut Child Schizophr 8:427–439, 1978

    Article  Google Scholar 

  • Cantwell DP: Familial-genetic research with hyperactive children, in Cantwell DP (ed): The Hyperactive Child. New York, Spectrum Publications, 1975, pp. 93–105.

    Google Scholar 

  • Connors CK: A teacher rating scale for use in drug studies with children. Am J Psychiatry 126:884–888, 1969

    Google Scholar 

  • Freedman LS, Ohuchi T, Goldstein M, et al.: Changes in human serum dopamine-beta-hydroxylase activity with age. Nature 236:310–311, 1972

    Article  PubMed  CAS  Google Scholar 

  • Frewin DB, Downey JA, Levitt M: The effect of heat, cold and exercise on dopamine-beta-hydroxylase activity in man. Can J Physiol Pharmacol 51:986–989, 1973

    Article  PubMed  CAS  Google Scholar 

  • Fijita K, Maruta K, Teradaira R, et al.: Dopamine-beta-hydroxylase activity in human cerebrospinal fluid and serum. J Neurochem 29:1141–1142, 1977

    Article  Google Scholar 

  • Firestone P, Lewy F, Douglas V: Hyperactivity and physical anomalies. Can Psychiatr Assoc J 21: 23–26, 1976

    PubMed  CAS  Google Scholar 

  • aGerwirtz GP, Kopin IJ: Release of dopamine-beta-hydroxylase with norepinephrine during cat splenic stimulation. Nature 227:406–407, 1970

    Article  Google Scholar 

  • Gittelman-Klein R, Klein DF: Methylphenidate effects in learning disabilities. Arch Gen Psychiatry 3:655–664, 1976

    Article  Google Scholar 

  • Gittelman-Klein R, Klein DF, Abikoff H, et al.: Relative efficacy of methylphenidate and behavior modification in hyperkinetic children: An interim report. J Abnorm Child Psychol 4:361–379, 1976b

    Article  CAS  Google Scholar 

  • Goldstein M, Freedman LS, Ebstein RP, et al.: Human serum dopamine-beta-hydroxylase: Relationship to sympathetic activity in physiological and pathological states, in Usdin E (ed): Neuropsychopharmacology of Monoamines and Their Regulatory Enzymes. New York, Raven Press, 1974, pp 105–119

    Google Scholar 

  • Horwitz DR, Alexander RW, Lovenberg W, Keiser H: Human serum dopamine-beta-hydroxylase. Circ Res 32:594–599, 1973

    PubMed  CAS  Google Scholar 

  • Kaufman S, Friedman H: Dopamine-beta-hydroxylase. Pharmacol Rev 17:71–100, 1965

    PubMed  CAS  Google Scholar 

  • Knobloch R, Pasamanick B: The developmental behavioral approach to the neurologic examination in infancy. Child Dev 3:181–198, 1962

    Google Scholar 

  • Lerner P, Goodwin FK, van Kammen DP, et al.: Dopamine-beta-hydroxylase in the cerebrospinal fluid of psychiatric patients. Biol Psychiatry 13:685–693, 1978

    PubMed  CAS  Google Scholar 

  • Levitt M, Dunner DL, Mendlewicz J, et al.: Plasma dopamine-beta-hydroxylase activity in affective disorders. Psychopharmacologia (Berlin) 46:205–210, 1976

    Article  CAS  Google Scholar 

  • Levitt M, Mendlewicz J: A genetic study of plasma dopamine-beta-hydroxylase in affective disorder, in Mendlewicz J (ed): Genetics and Psychopharmacology. Basel, Brussels, S. Karger, 1975, pp 89–98

    Google Scholar 

  • Lovenberg W, Bruckwick EA, Alexander RW, et al.: Evaluation of serum dopamine-beta-hydroxylase activity as an index of sympathetic nervous activity in man, in Usdin E (ed): Neuropsychopharmacology of Monoamines and Their Regulatory Enzymes. New York, Raven Press, 1974, pp 121–128

    Google Scholar 

  • Mendlewicz J, Levitt M, Fleiss JL: A genetic study of plasma dopamine-beta-hydroxylase activity in man. Acta Genet Med Gemellol (Roma) 24:105–110, 1975

    CAS  Google Scholar 

  • Molinoff PB, Nelson DL, Orcutt JC: Dopamine-beta-hydroxylase and the regulation of the noradrenergic neuron, in Usdin E (ed): Neuropsychopharmacology of Monoamines and Their Regulatory Enzymes. New York, Raven Press, 1974, pp 95–104

    Google Scholar 

  • Nagatsu T, Udenfriend S: Photometric assay of dopamine-beta-hydroxylase activity in human blood. Clin Chem 18:980–983, 1972

    PubMed  CAS  Google Scholar 

  • Okada T, Ohta T, Shinoda T, et al.: Dopamine-beta-hydroxylase activity in serum and cerebrospinal fluid in neuropsychiatric diseases. Neurop-sychobiology 2:139–144, 1976

    CAS  Google Scholar 

  • Pasamanick B, Knobloch H: Brain damage and reproductive casualty. Am J Orthopsychiatry 30:298–305, 1960

    Article  PubMed  CAS  Google Scholar 

  • Pasamanick B, Rogers M, Lilienfeld A: Pregnancy experience and the development of behavior disorders in children. Am J Psychiatry 112:613 (1956)

    PubMed  CAS  Google Scholar 

  • Rapoport J, Prandoni C, Renfield M, et al.: Newborn dopamine-beta-hydroxylase, minor physical anomalies, and infant temperament. Am J Psychiatry 134:676–678, 1977

    PubMed  CAS  Google Scholar 

  • Rapoport JL, Quinn PO, Lamprecht F: Minor physical anomalies and plasma dopamine-beta-hydroxylase activity in hyperactive boys. Am J Psychiatry 131:386–389, 1974

    PubMed  CAS  Google Scholar 

  • Rapoport JL, Quinn PO: Minor physical anomalies (stigmata) and early developmental deviation: A major biologic subgroup of “hyperactive children.” Int J Ment Health 4:29–44, 1975

    Google Scholar 

  • Ross SB, Wetterberg L, Myrked M: Genetic control of plasma dopamine-beta-hydroxylase. Life Sci 12:529–532, 1973

    Article  PubMed  CAS  Google Scholar 

  • Sandberg ST, Rutter M, Taylor E: Hyperkinetic disorder in psychiatric clinic attenders. Dev Med Child Neurol 20:279–299, 1978

    Article  PubMed  CAS  Google Scholar 

  • Smith D, Bostian K: Congenital anomalies associated with idiopathic mental retardation. J Pediatr 65:189–196, 1964

    Article  PubMed  CAS  Google Scholar 

  • Steg JP, Rapoport JC: Minor physical anomalies in normal, neurotic, learning disabled, and severely disturbed children. J Aut Child Schizophr 5:299–307, 1975

    Article  CAS  Google Scholar 

  • US Department of Health, Education, and Welfare: ECDEU Assessment Manual for Psychopharmacology. Washington, DC, US DHEW Publication ADM-76–338, 1976, pp 300–303

    Google Scholar 

  • Waldrop M, Bell R: Minor physical anomalies and inhibited behavior in elementary school girls. J Child Psychol Psychiatry 17:113–122, 1976

    Article  PubMed  CAS  Google Scholar 

  • Waldrop M, Bell R, McLaughlin B, Halverson C: Newborn minor physical anomalies predict short attention span, peer aggression, and impulsivity at age three. Science 199:563–565, 1978

    Article  PubMed  CAS  Google Scholar 

  • Waldrop M, Halverson CE: Minor physical anomalies and hyperactive behavior in young children, in Hellmuth J (ed): The Exceptional Infant. New York, Brunner/Mazel, 1971, pp 343–380

    Google Scholar 

  • Waldrop M, Pedersen F, Bell RQ: Minor physical anomalies and behavior in preschool children. Child Dev 39:391–400, 1968

    Article  PubMed  CAS  Google Scholar 

  • Weinshilboum RM, Raymond FA, Weidman WH: Serum dopamine-beta-hydroxylase activity: Sibling-sibling correlation. Science 181:943–945, 1973

    Article  PubMed  CAS  Google Scholar 

  • Wender J: Minimal Brain Dysfunction in Children. New York, Wiley-Interscience, John Wiley & Sons, 1971

    Google Scholar 

  • Werry J: Developmental hyperactivity. Pediatr Clin North Am 15:581–598, 1968

    PubMed  CAS  Google Scholar 

  • Werry JS: Organic factors in childhood psychopathology, in Quay HC, Werry JS (eds): Psychopathological Disorders of Childhood. New York, John Wiley & Sons, 1972, p 83

    Google Scholar 

  • Wetterberg L, Gustauson KH, Backstrom M, et al.: Low dopamine-beta-hydroxylase in Downs syndrome. Clin Genet 3:152–153, 1972

    Article  PubMed  CAS  Google Scholar 

  • Wolff S: The contribution of obstetric complications to the etiology of behavior disorders in childhood. J Child Psychol Psychiatry 8:57–66, 1967

    Article  PubMed  CAS  Google Scholar 

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© 1984 Spectrum Publications, Inc.

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Mattes, J.A., Gittelman, R., Levitt, M. (1984). Subclassification of Hyperactive Children on the Basis of Minor Physical Anomalies and Plasma Dopamine-Beta-Hydroxylase Activity: An Attempted Replication. In: Greenhill, L.L., Shopsin, B. (eds) The Psychobiology of Childhood. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6701-7_8

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  • DOI: https://doi.org/10.1007/978-94-011-6701-7_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6703-1

  • Online ISBN: 978-94-011-6701-7

  • eBook Packages: Springer Book Archive

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