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Chromosomes Today

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Abstract

The analysis of chromosomes of mouse embryos permits detection of transmitted chromosome damage. The protocol involves the treatment of one parent (usually the male) with a clastogen, recovery of embryos and preparation of chromosomes for metaphase analysis.

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Author information

Authors and Affiliations

  1. Imperial Chemical Industries PLC, Pharmaceuticals Division, Mereside, Alderley Park, Macclesfield, SK10 4TG, UK

    R. Albanese

  2. Institut de Progenèse, 15, rue de l’Ecole de Médecine, 75270, Paris, Cédex 06, France

    J. L. Antoine & B. Dutrillaux

  3. Department of Zoology, University of Tennessee, Knoxville, TN, 37996, USA

    T. Ashley

  4. Sackler School of Medicine (Human Genetics), Tel-Aviv University, Ramat-Aviv, Israel

    L. Avivi & I. Kariv

  5. Dipartimento di Biologia, Sezione di Genetica, via Celoria 26, Milano, Italy

    C. Barigozzi, L. Baratelli & S. Profeta

  6. Dept. Cell Biology and Genetics, Erasmus University Rotterdam, The Netherlands

    C. R. Bartram, A. de Klein, A. Hagemeijer, G. Grosveld & D. Bootsma

  7. Plant Breeding Institute, Maris Lane, Trumpington, Cambridge, CB2 2LQ, UK

    Michael D. Bennett, J. B. Smith, J. P. Ward & J. S. Heslop-Harrison

  8. German Cancer Research Center, Heidelberg, Germany

    N. Blin & M. Kopun

  9. Department of Human Genetics, State University of Groningen, The Netherlands

    C. H. C. M. Buys & T. Koerts

  10. Departments of Human Genetics, State University of Groningen, The Netherlands

    C. H. C. M. Buys & A. Y. van der Veen

  11. Departments of Clinical Immunology, State University of Groningen, The Netherlands

    L. de Leij

  12. Institute of Comparative Anatomy, Rome University, Rome, Italy

    M. V. Civitelli & E. Capanna

  13. Institut de Progenèse, 15 rue de l’Ecole de Médecine, 75270, Paris cedex 06, France

    J. Couturier, B. Dutrillaux, U. Arnason & N. Mandahl

  14. U. 173 INSERM - ER.149 CNRS, Hôpital Necker-Enfants-Malades, 149 rue de Sévres, 75743, Paris Cedex 15, France

    N. Créau-Goldberg, C. Turleau, C. Cochet & J. de Grouchy

  15. Institute of Human Genetics, University of Amsterdam Sarphatistraat 217, 1018 BX, Amsterdam, The Netherlands

    A. J. J. Dietrich

  16. Galton Laboratory, Department Genetics & Biometry, University College London, Gower Street, London WC1, UK

    J. D. A. Delhanty, H. A. Mazzullo & H. M. G. Cooke

  17. Sackler School of Medicine (Human Genetics), Tel-Aviv University, Ramat-Aviv, Israel

    A. Dotan & L. Avivi

  18. Department of Anatomy, Duke University Medical Center, Durham, N. C., USA

    M. E. Dresser & M. J. Moses

  19. MRC External staff, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, 0X1 3RE, UK

    E. P. Evans

  20. MRC Mammalian Development Unit, Wolfson House (University College London), 4 Stephenson Way, London, NW1 2HE, UK

    P. B. Burgoyne

  21. Dipartimento di Genetica e Biologia Molecolare, Universitâ di Roma, Rome, 00185, Italy

    M. Ferraro & P. Lavia

  22. Institut für Humangenetik, Medizinische Hochschule Lübeck, Germany

    C. Fonatsch

  23. Abteilung Onkologie-Hämatologie, Medizinische Hochschule Hannover, Germany

    H. H. Kirchner, A. Pajunk, M. Schaadt, H. Burrichter & V. Diehl

  24. Cytogenetics Dept, The Queen Elizabeth Hospital, SouthAustralia, 5011

    J. H. Ford & C. G. Roberts

  25. Institut für Angewandte Genetik, Freie Universität Berlin, Albrecht-Thaer-Weg 6, 1000, Berlin 33, Germany

    B. Friebe & R. Vogel

  26. Department of Biology, Ben-Gurion University of the Negev, Beer Sheva, Israel

    M. Friedländer

  27. Institut für Medizinische Biologie und Humangenetik der Universität Graz, Harrachgasse 21/8, A-8010, Graz, Austria

    R. Gamperl

  28. lnstitut für Virologie, Deutsches Krebsforschungszentrum Heidelberg, Im Neuenheimer Feld 280, D-6900, Heidelberg, Germany

    E. Amtmann

  29. lnstitut für Klinische Virologie der Universität Erlangen-Nürnberg, Loschgestrasse 7, D-8520, Erlangen, Germany

    H. Pfister

  30. Institut f. Humangenetik d. Universität, Bismarckstr. 10, D-8520, Erlangen, Germany

    E. Gebhart & H. Wagner

  31. Czechoslovakia MRC Clinical and Population Cytogenetic Unit, Department of Medical Genetics, Prague, Edinburgh, Scotland

    P. Goetz, A. C. Chandley & R. M. Speed

  32. Section of Genetics, Service of Pathology, Juan Canalejo Hospital, La Coruña, Spain

    V. J. Goyanes

  33. lnstituto de Biología Celular (CSIC), Velazquez 144, Madrid-6, Spain

    J. B. Schvartzman

  34. Department of Oncology and Haematology, University of Hamburg, Martini Str. 52, D-2000, Hamburg 20, Germany

    U. Graeven, H. J. Weh & D. K. Hossfeld

  35. Genetics and Cell Biology Section, Biological Science Group, University of Connecticut, Storrs, CT, 06268, USA

    I. M. Greenblatt

  36. Department of Genetics, University of Helsinki and Helsinki Zoo, Finland

    U. Gripenberg, V. Söderlund, C. Wahlberg & L. Blomqvist

  37. Department of Embryology and Cytogenetics, Marseilles, France

    M. R. Guichaoua & J. M. Luciani

  38. Center for Sterility, Department of Obstetrics and Gynecology, Hópital Boucicaut, Paris, France

    D. Delafontaine

  39. Department of Cytogenetics, Hopital Saint Antoine, Paris, France

    J. L. Taillemite

  40. lnstitut für Humangenetik, University of Würzburg Koellikerstr. 2, D-8700, Würzburg, Germany

    T. Naaf & M. Schmid

  41. lnstitut für Humangenetik, University of Göttingen Nikolausberger Weg 5a, D-3400, Göttingen, Germany

    D. Grunert

  42. Abteilung Klinische Genetik, Prittwitzstrasse 6, D-7900, Ulm, Germany

    H. Hameister

  43. lnstitut für Humangenetik, Heubnerweg 6, D-1000, Berlin 19, Germany

    K. Sperling

  44. Department of Genetics and Cellbiology, State University Limburg, P.O.Box 616, 6200 MD, Maastricht, The Netherlands

    A. Hamers & J. Geraedts

  45. lnstitute for mentally Retardates, Maria Roepaan, Siebengewaldseweg 15, 6595 NX, Ottersum, The Netherlands

    P. Jongbloet & G. Peeters

  46. Pharmacology Department, AB Leo, Box 941, S-251 09, Helsingborg, Sweden

    B. Hartley-Asp

  47. The Swedish University of Agricultural Sciences, Department of Crop Genetics and Breeding, S-268 00, Svalöv, Sweden

    W. K. Heneen

  48. Laboratorium voor Antropogenetika, VUB, Pleinlaan 2, 1050, Brussel, Belgium

    L. Hens, M. Kirsch-Volders & C. Susanne

  49. Laboratorium voor Medische Genetika, VUB, Laarbeeklaan 103, 1090, Brussel, Belgium

    L. Hens

  50. Institut für Pathologie der MHL, Lübeck, Fed. Rep. Germany

    E. W. Herbst, H. Winking, C. P. Claussen, B. Putz, D. Sellin, U. Kolbus & A. Gropp

  51. Plant Breeding Institute, Maris Lane, Trumpington, Cambridge CB2 2LQ, UK

    J. S. Heslop-Harrison & M. D. Bennett

  52. Institute of Human Genetics, Sarphatistraat 217, 1018 BX, Amsterdam, The Netherlands

    C. Heyting, A. J. J. Dietrich, F. Koperdraad & E. J. W. Redeker

  53. Dept. Medicine, Baylor, Houston, TX, 77030, USA

    G. Holmquist & M. Goldman

  54. Institute of Molecular Cytogenetics, University of Lund, Tornavägen 13, S1223 63, Lund, Sweden

    Halina Jaworska

  55. Institut für Pathologie, Medizinische Hochschule Lübeck, Ratzeburger Allee 160, 2400, Lübeck, Germany

    R. Johannisson, H. Winking & A. Gropp

  56. Departments of Genetics and Molecular Biology, The Hebrew University, Jerusalem, 91904, Israel

    B. Kerem, R. Goitein, C. Richier, M. Marcus & H. Cedar

  57. Department of Human Genetics, University of Würzburg, Germany

    H. Koch & H. Hoehn

  58. Department of Human Genetics, University of Würzburg, Germany

    Manfred Kubbies

  59. Department of Pathology, University of Washington, Seattle, USA

    Peter S. Rabinovitch

  60. Institut für Genetik, Universität Düsseldorf, D-4000, Düsseldorf 1, Germany

    W. Kunz & G. Franz

  61. Departamento de Genética, Facultad de Biología, Univ. Complutense, Madrid, Spain

    J. R. Lacadena, M. C. Cermeno, J. Orellana & J. L. Santos

  62. Lab. de Biologie et Génétique Evolutives - CNRS - F 91190 Gif Lab. de Cytologie et de Spectroscopie Biomoléculaire - U.E.R., Biomédicale, F 93000, Bobigny, France

    F. Lemeunier & C. Derbin

  63. Departments of Pediatrics and Medical Biochemistry, The University of Calgary, Calgary, Alberta, Canada, T2N 4N1

    C. C. Lin, D. I. Hoar & J. J. Hoo

  64. Department of Zoology, University of Leicester, Leicester, LE1 7RH, UK

    H. C. Macgregor, S. Sims, H. A. Horner & P. Pellatt

  65. Department of Genetics, University of Aberdeen, 2 Tillydrone Avenue, Aberdeen, AB9 2TN, Scotland

    J. M. Mackay & D. P. Fox

  66. Woodland Hospital, Aberdeen, AB9 2YS, Scotland

    P. W. Brunt & A. W. Johnston

  67. Oregon Health Sciences University, Portland, Oregon, USA

    R. E. Magenis, J. Chamberlin, L. Allen, D. Tomar, S. Olson & T. Donlon

  68. Departments of Genetics and Molecular Biology, University of Rome, Italy

    P. Marlekaj, A. Balcini & A. Fantoni

  69. Departments of Human Biopathology, University of Rome, Italy

    A. de Capoa

  70. Department of Genetics, University of Göteborg, Sweden

    T. Martinsson, B. Dahllöf & G. Levan

  71. Cancer Institute (Cell Biology), Toshima-ku, Tokyo 170, Japan

    S. Matsukuma & T. Utakoji

  72. lnstituto de Genética (C.S.I.C.), Velázquez, 144, Madrid-6, Spain

    J. del Mazo

  73. lnstituto de Virología y Genética Molecular (C.S.I.C.), Centro de Biología Molecular. U. Autónoma, Madrid-34, Spain

    J. Avila

  74. Dept. Human Genetics and Development, Columbia Univ, New York, NY, 10032, USA

    D. A. Miller, S. I. Feinstein & O. J. Miller

  75. Unité de Biologie Moléculaire du Gène, InstitutPasteur, 25 rue du Dr. Roux, 75724, Paris, France

    T. Morita, C. Delarbre, G. Gachelin & P. Kourilsky

  76. Zoologisches Institut, Luisenstr. 14, 8000, München, Germany

    K. Moritz

  77. Department of Cytogenetics, National Institute of Genetics, Mishima, Japan

    K. Moriwaki, N. Miyashita & H. T. Imai

  78. Lanzhou Institute of Biological Products, Lanzhou, China

    C. H. Wang

  79. Laboratoire de Génétique du Cerem, Faculté des Sciences, Montpellier, France

    F. Bonhomme

  80. McGill Centre for Human Genetics, McGill University, Montreal, Canada

    M. Murer-Orlando & A. C. Peterson

  81. Institute of Human Genetics, Berlin, Germany

    H. Neitzel & K. Sperling

  82. lnstitute of Physiological Chemistry, München, Germany

    J. Bogenberger & F. Fittler

  83. Institute of Human Genetics, Heubnerweg 6, 1000, Berlin 19, Germany

    H. Neitzel, M. Gaenge, C. Schulze & K. Sperling

  84. Institute of Human Genetics, Berlin, Germany

    H. Nietzel & K. Sperling

  85. Rudolf-Virchow-Hospital, Berlin, Germany

    F. Nürnberger

  86. lnstitute of Human Genetics, Würzburg, Germany

    H. Höhn

  87. Dept. of Human Genetics, University of Leiden, The Netherlands

    G. J. B. van Ommen

  88. Pediatrics Department AMC, University of Amsterdam, The Netherlands

    F. Baas

  89. Biochemical Laboratory, University of Groningen, The Netherlands

    A. C. Arnberg

  90. Netherlands

    P. L. Pearson & J. J. M. De Vijilder

  91. Dept. of Human Genetics, University of Leiden, Netherlands

    G. J. B. van Ommen, E. Bakker, M. Hofker, M. C. Wapenaar & P. L. Pearson

  92. MRC Human Biochemical Genetics Unit, 4 Stephenson Way, London, NW1 2HE, UK

    J. M. Parrington, L. F. West & S. Povey

  93. Istituto di Biologia Generale e Genetica Medica, Università di Pavia, C.P. 217, I-27100, Pavia, Italy

    F. Pasquali, R. Casalone & P. Bernasconi

  94. lnstitut für Humangenetik;Medizinische Hochschule Lübeck, Ratzeburger Allee 160, D-2400, Lübeck, Germany

    J. Paul, U. Froster-Iskenius & E. Schwinger

  95. Klinik für Psychiatrie, Medizinische Hochschule Lübeck, Ratzeburger Allee 160, D-2400, Lübeck, Germany

    W. Moje

  96. Dept. Human Genetics, Netherlands

    P. O. Pearson, G. C. Beverstock & H. Veenema

  97. University Hospital, Leiden, Netherlands

    J. J. v.d Kamp

  98. Departament de Genética, Fac. de Ciències, Palma de Mallorca, Spain

    E. Petitpierre

  99. Chromosome Laboratory, Section of Clinical Genetics, Department of Obstetrics and Gynaecology and Department of Paediatrics, Rigshospitalet, Copenhagen, Denmark

    J. Philip & C. Lundsteen

  100. Dept. Histochem. Cytochem, Univ. of Leiden, 72 Wassenaarseweg, 2333 AL, Leiden, Netherlands

    M. van der Ploeg, A. C. van Prooijen-Knegt, J. G. J. Bauman & P. van Duijn

  101. Departamento de Genética, Facultad de Biología, Universidad Complutense, Madrid-3, Spain

    M. J. Puertas, A. de la Pena, B. Estades & F. Merino

  102. Department of Zoology, University of Delhi, Delhi, 110 007, India

    S. R. V. Rao, B. K. Thelma & R. C. Juyal

  103. Malaria Research Centre, 22 Shamnath Marg, Delhi, 110 054, India

    K. Vasantha

  104. Laboratory of Genetics, Department of Pathology, Memorial Sloan Kettering Cancer Centre, 1275 York Avenue, NewYork, 10021, USA

    S. C. Jhanwar

  105. Faculté de Médecine, Institut d’Embryologie, 11 rue Humann, 67085, Strasbourg, France

    Ch Ratomponirina & Y. Rumpler

  106. Tulasne University, New Orleans, USA

    A. Hamilton

  107. Duke University, Durham, USA

    M. Moses

  108. Department of Biology, Ben Gurion University of the Negev, Beersheba and Department of Genetics, Weizmann Institute of Science, Rehovot, Israel

    D. Raveh & A. Ben-Zeoev

  109. Dipartimento di Biologia Animale, Università di Pavia and Centro di Studio per l’Istochimica del C.N.R., Italy

    C. A. Redi & S. Garagna

  110. III Zoologisches Institut, Universität Göttingen, Germany

    C. N. R. Italy, I. Streichhan, E. Möhr, R. Westermann & U. Grossbach

  111. Department of Genetics, Universities of Göteborg and Lund, Sweden

    M. Robert-Nicoud, P. Sandberg, T. Martinsson, B. Dahllöf, G. Levan & A. Levan

  112. Institut für Genetik, Universität Düsseldorf, Universitätsstrasse 1, D-4000, Düsseldorf 1, Germany

    Mireille Schäfer & W. Kunz

  113. Institut für Humangenetik, Albertstr. 11, D-7800, Freiburg i.Br, Germany

    W. Schempp

  114. Faculty of Medicine, University of Nijmegen, The Netherlands

    J. M. J. C. Scheres, T. W. J. Hustinx & R. S. G. Holdrinet

  115. Institute of Cell Biology (CSIC), Velazquez 144, Madrid-6, Spain

    J. B. Schvartzman

  116. Section of Genetics, Juan Canalejo Hospital, La Coruña, Spain

    V. J. Goyanes

  117. Brookhaven Nat. Lab, Medical Department, Upton, New York, USA

    R. R. Tice

  118. Plant Breeding Institute, Maris Lane, Trumpington, Cambridge, CB2 2LQ, UK

    R. A. Finch & M. D. Bennett

  119. Institute of Botany, University of Vienna, Rennweg 14, 1030, Wien, Austria

    T. Schwarzacher

  120. Department of Agricultural Science, Parks Road, Oxford, OX1 3PF, UK

    J. B. Searle

  121. Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, 221005, India

    T. Sharma, S. Sen & N. Cheong

  122. Inst. Hum. Genet., Univ of Erlangen, Bismarckstr. 10, D-8520, Erlangen, Germany

    E. Siebert & J. Loidl

  123. Institute of Human Genetics, Sarphatistraat 217, 1018 BX, Amsterdam, The Netherlands

    R. M. Slater, R. M. Slater, J. de Kraker, P. A. Voute & J. F. M. Delemarre

  124. Emma Kinderziekenhuis, Spinozastraat 52, 1018 HJ, Amsterdam, The Netherlands

    W. Schempp

  125. Faculty of Medicine, University of Nijmegen, the Netherlands

    D. F. C. M. Smeets, T. W. J. Hustinx, J. M. J. C. Scheres & A. P. T. Smits

  126. Institut für Humangenetik, University of Würzburg, Koellikerstr. 2, D-8700, Würzburg, Germany

    E. Solleder, B. Inglin, B. Geile & M. Schmid

  127. Institut für Humangenetik und Anthropologie, 7800, Freiburg, Germany

    I. Somssich

  128. lnstitut für Humangenetik und Anthropologie, D-7800, Freiburg, Germany

    I. Somssich & E. Schwarz

  129. Abteilung Klinische Genetik, Prittwitzstrasse 6, D-7900, Ulm, Germany

    H. Hameister

  130. MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK

    R. M. Speed

  131. Abteilung Klinische Genetik der Universität, D-7900, Ulm, Germany

    G. Speit, K. Mehnert & W. Vogel

  132. Laboratoire d’Histologie-Embryologie, Faculté de Médecine, Bd Jean-Moulin, 13385, Marseille Cedex 5, France

    A. Stahl, J. M. Luciani, M. Hartung, M. Devictor & M. Guichaoua

  133. Institut de Puériculture, C.H.U., 67000, Strasbourg, France

    C. Stoll, M.-P. Roth & B. Dott

  134. Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark

    A. Tabor & J. Philip

  135. Danish Institute of Clinical Epidemiology, Copenhagen, Denmark

    M. Madsen

  136. Department of Medical Genetics, The J.F. Kennedy Institute, 7 Gl. Landevej, DK-2600, Glostrup, Denmark

    N. Tommerup

  137. Institut für Biologie, Medizinische Hochschule Lübeck, D-2400, Lübeck, Germany

    W. Traut

  138. U.173 INSERM - ER.149 CNRS, Hôpital Necker-Enfants-, Malades 149, rue de Sèvres, 75743, Paris, France

    C. Turleau, F. Chavin-Colin, C. Junien & J. de Grouchy

  139. The Montreal Children’s Hospital, Department of Pathology, Montreal, Canada

    M. Vekemans

  140. Department of Hematology, McGill University, Montreal, Canada

    D. Esseltine

  141. Institut de Recherches Scientifiques sur le Cancer, L.R.A.C.C., BP No 08-94802, Villejuif Cédex, France

    W. Venegas, Cl Lasne & I. Chouroulinkov

  142. Institut de Biologia Fonamental “V. Villar Palasí” Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain

    F. Vidal, J. Navarro, C. Templado & J. Egozcue

  143. ER CNRS no 264, 15 rue de l’Ecole de Médecine, 75270, Paris Cedex, France

    E. Viegas-Péquignot & B. Dutrillaux

  144. U.E.R. Médecine-Biologie, Univ. Paris XIII, 74 rue Marcel Cachin, 93012, Bobigny Cedex, France

    C. Derbin & E. Taillandier

  145. Centre de Biophysique Moléculaire, CNRS, 1A Av. de la Recherche Scientifique, 45045, Orléans Cedex, France

    B. Malfoy & M. Leng

  146. Department of Biology, University of Turku, 20500, Turku 50, Finland

    Y. Viinikka

  147. Bundesgesundheitsamt, Max von Pettenkofer Institut, Abteilung für Chemikalienbewertung, Thielallee 88-92, 1000, Berlin (West) 33, Germany

    R. Vogel & H. Spielmann

  148. Abteilung Klinische Genetik der Universität, D-7900 Ulm, Oberer Eselsberg, Germany

    W. Vogel, S. Boldin & G. Speit

  149. Institut de Progénèse, 15 rue de l’Ecole de Médicine, 75006, Paris, France

    V. T. Volobouev

  150. Birth Defects Research Institute, Royal Children’s Hospital, Parkville, 3052, Australia

    G. C. Webb

  151. Pathology Department, Royal Women’s Hospital, Carlton, 3053, Australia

    E. Krumins

  152. Institute of Human Genetics, Heubnerweg 6, D-1000, Berlin 19, Germany

    R.-D. Wegner, E.-L. Lüdtke & K. Sperling

  153. Inst. f. Biologie, Medizinische Hochschule Lübeck, Germany

    A. Weith

  154. Department of Genetics and Human Variation, La Trobe University, Bundoora, 3083, Australia

    M. Westerman, R. Thomson & A. Sinclair

  155. Plant Genetics, The Weizmann Institute of Science, Rehovot, Israel

    Y. Z. Yacobi & M. Feldman

  156. Department of Biological Sciences, Bowling Green State University, Ohio, 43403, USA

    J. S. Yoon

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Editor information

Editors and Affiliations

  1. Plant Breeding Institute, Maris Lane, Trumpington, CB2 2LQ, Cambridge, UK

    M. D. Bennett

  2. Institut für Pathologie, Medizinische Hochschule Lübeck, Ratzeburger Allee 160, D-2400, Lübeck 1, West Germany

    A. Gropp

  3. Institut für Humangenetik und Anthropologie der Universität, Albertstrasse 11, D-7800, Freiburg/i. Br., West Germany

    U. Wolf

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© 1984 The Organising Committee of the VIII International Chromosome, Conference, Lübeck

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Albanese, R. et al. (1984). Abstracts of Selected Posters. In: Bennett, M.D., Gropp, A., Wolf, U. (eds) Chromosomes Today. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9163-3_26

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  • DOI: https://doi.org/10.1007/978-94-010-9163-3_26

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-9165-7

  • Online ISBN: 978-94-010-9163-3

  • eBook Packages: Springer Book Archive

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