Abstract
In plants, algae, cyanobacteria and some other bacterial species 5-aminolevulinate (ALA) is synthesized from glutamate (1–6). This reaction sequence involves ligation of glutamate to a tRNAGlu species and subsequent reduction to glutamate-1-semialdehyde (GSA) (7). The conversion of GSA to ALA is then catalysed by GSA-aminotransferase (E.C. 5.4.3.8.) (2,8). Dependent on the requirement of pyridoxamine-phosphate (PAMP) or pyridoxal-phosphate (PALP) for activity, either 4,5-diaminovalerate (8–10) or 4,5-dioxovalerate (DOVA) (5,11,12) are proposed as intermediates.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Castelfranco, P.A. and Beale, S.I. (1983) Annu. Rev. Plant Physiol 34, 241–278
Kannangara, C.G. and Gough, S.P. (1978) Carlsberg Res. Commun. 43, 185–194.
Kannangara, C.G., Gough, S.P., Bruyant, Ph., Hoober, J.K., Kahn, A. and v. Wettstein, D. (1988) TIBS 13, 139–143.
Smith and Rogers (1988) In: Proceedings of the Phytochemical Society of Europe. Biochemistry of the algae and cyanobacteria. (Rogers, L.J. and Gallon, J.R., eds.), Clarendon Press, Oxford, pp. 69–96.
Breu, V. and Dörnemann, D. (1988) Biochim. Biophys. Acta 967, 135–140.
Avissar, Y.J., Ormerod, J.G. and Beale, S.I. (1989) Arch. Microbiol. 151, 513–519.
Kannangara, C.G., Gough, S.P., Oliver, R.P. and Rasmussen, S.K. Carlsberg Res. Commun. 49, 417–437.
Grimm, B., Bull, A., Welinder, K.G., Gough, S.P. and Kannangara, C.G. (1989) Carlsberg Res. Commun. 54, 67–79.
Hoober, J.K., Kahn, A., Ash, D.E., Gough, S. and Kannangara, C.G. (1988) Carlsberg Res. Commun. 53, 11–25
Bull, A.D., Grimm, B., Breu, V. Kannangara, C.G., Rogers, L.J. and Smith, A.J. (in preparation)
Dörnemann, D. and Senger, H. (1980) Biochim. Biophys. Acta 628, 35–45.
Breu, V., Kah, A and Dörnemann, D. (1988) Biochim. Biophys. Acta 964, 61–68.
Gough, S.P. and Kannangara, C.G. (1989) Carlsberg Res. Commun. (in press)
Smith, A J., London, J. and Stanier, R.Y. (1967) J. Bacteriol. 94, 972–983.
Breu, V. (1988) In: Wissenschaftliche Forschungsbeiträge Biologie, Biochemie, Chemie (Ch. Intemann and A Intemann, eds.) Intemann Verlag, München.
Kannangara, C.G., Gough, S.P. and Girnth, C. (1981), In: Photosynthesis V. Chloroplast Development (G. Akoyunoglou, ed.), Balaban Int. Sc. S., Philadelphia.
Dörnemann, D., Kotzabasia, K., Richter, P., Breu, V. and Senger, H. (1989) Botanica Acta 102, 112–115.
O’Neill, G.P., Peterson, D.M., Schön, A., Chen, M.-W. and Söll, D. (1988) J. of Bact. 170, 3810–3816.
Friedmann, H.C., Thauer, R.K., Gough, S.P. and Kannangara, C.G. (1987) Carlsberg Res. Commun. 52, 363–371.
Bull, A.D., Pakes, J.F., Hoult, R.C. Rogers, L.J. and Smith, A.J. (1989) Biochem Soc Trans (in press)
Avissar, Y. J. and Beale, S.I. (1989) Plant Physiol. 89, 852–859.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer Science+Business Media New York
About this chapter
Cite this chapter
Bull, A.D., Breu, V., Smith, A.J., Kannangara, C.G. (1990). δ-Aminolevulinate (ALA) Synthesis in Synechococcus 6301: Requirement for tRNAGlu, and Pyridoxamine Phosphate. In: Baltscheffsky, M. (eds) Current Research in Photosynthesis. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0511-5_615
Download citation
DOI: https://doi.org/10.1007/978-94-009-0511-5_615
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6716-4
Online ISBN: 978-94-009-0511-5
eBook Packages: Springer Book Archive