Current Thinking About Nature and Nurture

  • David S. Moore
Part of the History, Philosophy and Theory of the Life Sciences book series (HPTL, volume 1)


Theories about the origins of people’s biological and psychological characteristics have focused for centuries on the contributions of Nature and Nurture to development. Modern psychologists often maintain that it is an error to ask if Nature or Nurture determines the form of a particular trait, because the two types of factors interact during development. Instead, some of them have argued, the question of importance is: how much does each factor contribute to this process? This is the approach adopted by quantitative behavioral geneticists engaged in twin and/or adoption studies—research designed to yield heritability estimates for a wide variety of traits. In contrast, molecular biologists have learned that the dichotomy at the heart of such questions does not stand up to either conceptual or empirical scrutiny. In fact, it makes little sense to attempt to quantify the extent to which Nature versus Nurture contributes to a trait, precisely because these two classes of factors are always essential to—and interactive during—the development of both biological and psychological characteristics. Therefore, the question of importance is: how are our traits built during development? That is, how is it that genetic factors, proteins, cells, organs, organisms, and populations of individuals co-act to produce phenotypes in development? There are a number of related insights at the center of this discussion, including that the environments and experiences we encounter as we develop get inside of us in ways that alter our biological/genetic functioning, and that biological factors collaborate with environmental factors to build all of our organs, including our brains and their associated behaviors, cognitions, and emotions. Although the conceptualization of Nature and Nurture as dichotomous has a long history, evidence from the biological sciences indicates that it has outlived its usefulness. Consequently, those wishing to teach students about genetics, human nature, inheritance, and development would be well advised to refrain from framing their discussions in terms of this obsolete dichotomy.


Heritability Estimate Twin Study Psychological Characteristic Molecular Biologist Royal Jelly 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



I am very grateful to both Kostas Kampourakis and Lisa Gannett for their helpful comments in response to earlier drafts of this chapter.


  1. Aleman, A., E. Bronk, R.P.C. Kessels, H.P.F. Koppeschaar, and J. van Honk. 2004. A single administration of testosterone improves visuospatial ability in young women. Psychoneuroendocrinology 29: 612–617.CrossRefGoogle Scholar
  2. Amara, S.G., V. Jonas, M.B. Rosenfeld, E.S. Ong, and R.M. Evans. 1982. Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide ­products. Nature 298: 240–244.CrossRefGoogle Scholar
  3. Archer, J. 2006. Testosterone and human aggression: An evaluation of the challenge hypothesis. Neuroscience and Biobehavioral Reviews 30: 319–345.CrossRefGoogle Scholar
  4. Bateson, P. 2002. The corpse of a wearisome debate: Review of Steven Pinker’s The blank slate: The modern denial of human nature. Science, 297: 2212–2213.Google Scholar
  5. Bateson, P., and P. Gluckman. 2011. Plasticity, robustness, development and evolution. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
  6. Beach, F. 1955. The descent of instinct. Psychological Review 62: 401–410.CrossRefGoogle Scholar
  7. Beach, S.R.H., G.H. Brody, A.A. Todorov, T.D. Gunter, and R.A. Philibert. 2010. Methylation at SLC6A4 is linked to family history of child abuse: An examination of the Iowa adoptee sample. American Journal of Medical Genetics Part B 153B: 710–713.Google Scholar
  8. Beutler, E., M. Yeh, and V.F. Fairbanks. 1962. The normal human female as a mosaic of X-chromosome activity: Studies using the gene for G-6-PD deficiency as a marker. Proceedings of the National Academy of Sciences of the United States of America 48: 9–16.CrossRefGoogle Scholar
  9. Block, N. 1995. How heritability misleads about race. Cognition 56: 99–128.CrossRefGoogle Scholar
  10. Blumberg, M.S. 2005. Basic instinct: The genesis of behavior. New York: Thunder’s Mouth Press.Google Scholar
  11. Borghol, N., M. Suderman, W. McArdle, A. Racine, M. Hallett, M. Pembrey, C. Hertzman, C. Power, and M. Szyf. 2012. Associations with early-life socio-economic position in adult DNA methylation. International Journal of Epidemiology 41: 1–13. doi: 10.1093/ije/dyr147.Google Scholar
  12. Carey, N. 2011. The epigenetics revolution. London: Icon Books.Google Scholar
  13. Castéra, J., M. Abrougui, O. Nisiforou, J. Turcinaviciene, T. Sarapuu, B. Agorram, F. Calado, and G. Carvalho. 2008. Genetic determinism in school textbooks: A comparative study conducted among sixteen countries. Science Education International 19: 163–184.Google Scholar
  14.  Crick, F.H.C. 1958. On protein synthesis. In Symposia of the Society for Experimental Biology, XII, The biological replication of macromolecules, 138–163. Cambridge: Cambridge University Press.Google Scholar
  15. Crick, F. 1970. Central dogma of molecular biology. Nature 227: 561–563.CrossRefGoogle Scholar
  16. Davenport, M.H., and M.R. Cabrero. 2009. Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet. The Journal of Physiology 587: 3423–3424.CrossRefGoogle Scholar
  17. Davis, S., B. Bozon, and S. Laroche. 2003. How necessary is the activation of the immediate early gene zif 268 in synaptic plasticity and learning? Behavioural Brain Research 142: 17–30.CrossRefGoogle Scholar
  18. Deater-Deckard, K., S.A. Petrill, L.A. Thompson, and L.S. DeThorne. 2006. A longitudinal behavioral genetic analysis of task persistence. Developmental Science 9: 498–504.CrossRefGoogle Scholar
  19. DeCasper, A.J., and M.J. Spence. 1986. Prenatal maternal speech influences newborns’ perception of speech sound. Infant Behavior & Development 9: 133–150.CrossRefGoogle Scholar
  20. Dobzhansky, T. 1955. Evolution, genetics, and man. New York: Wiley.Google Scholar
  21. dos Santos, V.C., L.M. Joaquim, and C.N. El-Hani. 2012. Hybrid deterministic views about genes in biology textbooks: A key problem in genetics teaching. Science & Education 21: 543–578. doi: 10.1007/s11191-011-9348-1.CrossRefGoogle Scholar
  22. Edwards, D.A., K. Wetzel, and D.R. Wyner. 2006. Intercollegiate soccer: Saliva cortisol and testosterone are elevated during competition, and testosterone is related to status and social connectedness with teammates. Physiology and Behavior 87: 135–143.CrossRefGoogle Scholar
  23. Eisenberg, L. 2004. Social psychiatry and the human genome: Contextualising heritability. The British Journal of Psychiatry 184: 101–103.CrossRefGoogle Scholar
  24. Galton, F. 1874. English men of science: Their nature and nurture. London: Macmillan.CrossRefGoogle Scholar
  25. Galton, F. 1907. Inquiries into human faculty and its development. London/New York: J. M. Dent/E. P. Dutton (Originally published in 1883).CrossRefGoogle Scholar
  26. Gericke, N.M., and M. Hagberg. 2010. Conceptual variation in the depiction of gene function in upper secondary school textbooks. Science & Education 19: 963–994.CrossRefGoogle Scholar
  27. Gilbert, S.F. 2003. The reactive genome. In Origination of organismal form: Beyond the gene in developmental and evolutionary biology, ed. G.B. Müller and S.A. Newman, 87–101. Cambridge, MA: MIT Press.Google Scholar
  28. Gottesman, I.I. 1963. Genetic aspects of intelligent behavior. In The handbook of mental deficiency, ed. N. Ellis, 253–296. New York: McGraw-Hill.Google Scholar
  29. Gottlieb, G. 1991a. Experiential canalization of behavioral development: Theory. Developmental Psychology 27: 4–13.CrossRefGoogle Scholar
  30. Gottlieb, G. 1991b. Experiential canalization of behavioral development: Results. Developmental Psychology 27: 35–39.CrossRefGoogle Scholar
  31. Gottlieb, G. 1992. Individual development and evolution: The genesis of novel behavior. New York: Oxford University Press.Google Scholar
  32. Gottlieb, G. 1997. Synthesizing nature-nurture: Prenatal roots of instinctive behavior. Mahwah: Lawrence Erlbaum Associates.Google Scholar
  33. Gottlieb, G. 2007. Probabilistic epigenesis. Developmental Science 10: 1–11.CrossRefGoogle Scholar
  34. Griffiths, P.E., and R.D. Gray. 1994. Developmental systems and evolutionary explanation. The Journal of Philosophy XCI: 277–304.CrossRefGoogle Scholar
  35. Griffiths, P.E., and J. Tabery. 2008. Behavioral genetics and development: Historical and conceptual causes of controversy. New Ideas in Psychology 26: 332–352.CrossRefGoogle Scholar
  36. Hall, B.K. 1988. The embryonic development of bone. American Scientist 76: 174–181.Google Scholar
  37. Hambrick, D.Z., and E.J. Meinz. 2011a. Limits on the predictive power of domain-specific experience and knowledge in skilled performance. Current Directions in Psychological Science 20: 275–279.CrossRefGoogle Scholar
  38. Hambrick, D.Z., and E.J. Meinz. 2011b. Sorry strivers: Talent matters. The New York Times. Retrieved from Accessed 24 Mar 2013.
  39. Harper, L.V. 2005. Epigenetic inheritance and the intergenerational transfer of experience. Psychological Bulletin 131: 340–360.CrossRefGoogle Scholar
  40. Harris, J.R. 2009. The nurture assumption: Why children turn out the way they do. New York: The Free Press.Google Scholar
  41. Herrnstein, R.J., and C. Murray. 1994. The Bell curve: Intelligence and class structure in American life. New York: The Free Press.Google Scholar
  42. Hoek, H.W., A.S. Brown, and E. Susser. 1998. The Dutch famine and schizophrenia spectrum disorders. Social Psychiatry and Psychiatric Epidemiology 33: 373–379.CrossRefGoogle Scholar
  43. Jablonka, E., and M.J. Lamb. 2005. Evolution in four dimensions: Genetic, epigenetic, behavioral, and symbolic variation in the history of life. Cambridge, MA: The MIT Press.Google Scholar
  44. Johannsen, W. 1911. The genotype conception of heredity. American Naturalist 45: 129–159.CrossRefGoogle Scholar
  45. Johnson, W., E. Turkheimer, I.I. Gottesman, and T.J. Bouchard. 2009. Beyond heritability: Twin studies in behavioral research. Current Directions in Psychological Science 18: 217–220.CrossRefGoogle Scholar
  46. Johnston, T.D. 1987. The persistence of dichotomies in the study of behavioral development. Developmental Review 7: 149–182.CrossRefGoogle Scholar
  47. Johnston, T.D. 2010. Developmental systems theory. In Oxford handbook of developmental behavioral neuroscience, ed. M.S. Blumberg, J.H. Freeman, and S.R. Robinson, 12–29. New York: Oxford University Press.Google Scholar
  48. Johnston, T.D., and L. Edwards. 2002. Genes, interactions, and the development of behavior. Psychological Review 109: 26–34.CrossRefGoogle Scholar
  49. Keller, E.F. 2010. The mirage of a space between nature and nurture. Durham: Duke University Press.Google Scholar
  50. Kevles, D.J. 1995. In the name of eugenics. Cambridge, MA: Harvard University Press.Google Scholar
  51. King, A.P., M.J. West, and M.H. Goldstein. 2005. Non-vocal shaping of avian song development: Parallels to human speech development. Ethology 111: 101–117.CrossRefGoogle Scholar
  52. Laland, K.N., J. Odling-Smee, and M.W. Feldman. 2001. Niche construction, ecological inheritance, and cycles of contingency in evolution. In Cycles of contingency: Developmental systems and evolution, ed. S. Oyama, P.E. Griffiths, and R.D. Gray, 117–126. Cambridge, MA: The MIT Press.Google Scholar
  53. Lehrman, D.S. 1953. A critique of Konrad Lorenz’s theory of instinctive behavior. The Quarterly Review of Biology 28: 337–363.CrossRefGoogle Scholar
  54. Lewkowicz, D.J. 2011. The biological implausibility of the nature–nurture dichotomy and what it means for the study of infancy. Infancy 16: 331–367.CrossRefGoogle Scholar
  55. Lewontin, R.C. 1974. Annotation: The analysis of variance and the analysis of causes. American Journal of Human Genetics 26: 400–411.Google Scholar
  56. Lewontin, R.C. 1983. Gene, organism and environment. In Evolution from molecules to men, ed. D.S. Bendall, 273–285. Cambridge: Cambridge University Press.Google Scholar
  57. Lewontin, R.C. 2000. The triple helix: Gene, organism, and environment. Cambridge, MA: Harvard University Press.Google Scholar
  58. Lewontin, R.C., S. Rose, and L.J. Kamin. 1984. Not in our genes. New York: Pantheon.Google Scholar
  59. Lickliter, R. 2000. An ecological approach to behavioral development: Insights from comparative psychology. Ecological Psychology 12: 319–334.CrossRefGoogle Scholar
  60. Lickliter, R. 2008. The growth of developmental thought: Implications for a new evolutionary psychology. New Ideas in Psychology 26: 353–369.CrossRefGoogle Scholar
  61. Lickliter, R., and T.D. Berry. 1990. The phylogeny fallacy: Developmental psychology’s misapplication of evolutionary theory. Developmental Review 10: 348–364.CrossRefGoogle Scholar
  62. Lickliter, R., and H. Honeycutt. 2010. Rethinking epigenesis and evolution in light of developmental science. In Oxford handbook of developmental behavioral neuroscience, ed. M.S. Blumberg, J.H. Freeman, and S.R. Robinson, 30–47. New York: Oxford University Press.Google Scholar
  63. Masataka, N. 1993. Effects of experience with live insects on the development of fear of snakes in squirrel monkeys, Saimirisciureus. Animal Behaviour 46: 741–746.CrossRefGoogle Scholar
  64. McGowan, P.O., A. Sasaki, A.C. D’Alessio, S. Dymov, B. Labonté, M. Szyf, and M.J. Meaney. 2009. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nature Neuroscience 12: 342–348.Google Scholar
  65. McKenzie, C.A., K. Wakamatsu, N.A. Hanchard, T. Forrester, and S. Ito. 2007. Childhood malnutrition is associated with a reduction in the total melanin content of scalp hair. British Journal of Nutrition 98: 159–164.CrossRefGoogle Scholar
  66. Meaney, M.J. 2010. Epigenetics and the biological definition of gene X environment interactions. Child Development 81: 41–79.CrossRefGoogle Scholar
  67. Mehta, P.H., and J. Beer. 2010. Neural mechanisms of the testosterone–aggression relation: The role of orbitofrontal cortex. Journal of Cognitive Neuroscience 22: 2357–2368.CrossRefGoogle Scholar
  68. Mello, C.V., D.S. Vicario, and D.F. Clayton. 1992. Song presentation induces gene expression in the songbird forebrain. Proceedings of the National Academy of Sciences of the United States of America 89: 6818–6822.CrossRefGoogle Scholar
  69. Mennella, J.A., C.P. Jagnow, and G.K. Beauchamp. 2001. Prenatal and postnatal flavor learning by human infants. Pediatrics 107(6): e88.CrossRefGoogle Scholar
  70. Moore, D.S. 2002. The dependent gene: The fallacy of “nature vs. nurture.” New York: Times Books/Henry Holt & Co.Google Scholar
  71. Moore, D.S. 2006. A very little bit of knowledge: Re-evaluating the meaning of the heritability of IQ. Human Development 49: 347–353.CrossRefGoogle Scholar
  72. Moore, D.S. 2008a. Espousing interactions and fielding reactions: Addressing laypeople’s beliefs about genetic determinism. Philosophical Psychology 21: 331–348.CrossRefGoogle Scholar
  73. Moore, D.S. 2008b. Individuals and populations: How biology’s theory and data have interfered with the integration of development and evolution. New Ideas in Psychology 26: 370–386.CrossRefGoogle Scholar
  74. Moore, D.S. 2011. Evelyn, Fox, Keller. 2010. The mirage of a space between nature and nurture. Durham: Duke University Press. ISBN: 978-0-8223-4731-6, 107 pages, price: $18.95. Science & Education. doi:  10.1007/s11191-011-9374-z
  75. Moore, D.S. 2013. Behavioral genetics, genetics, & epigenetics. In Oxford handbook of developmental psychology, ed. P.D. Zelazo, 91–128. New York: Oxford University Press.Google Scholar
  76. Niv, S., C. Tuvblad, A. Raine, P. Wang, and L.A. Baker. 2012. Heritability and longitudinal stability of impulsivity in adolescence. Behavior Genetics 42(3): 378–392. doi: 10.1007/s10519-011-9518-6.CrossRefGoogle Scholar
  77. Noble, D. 2006. The music of life: Biology beyond genes. New York: Oxford University Press.Google Scholar
  78. Oberlander, T.F., J. Weinberg, M. Papsdorf, R. Grunau, S. Misri, and A.M. Devlin. 2008. Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 3: 97–106.CrossRefGoogle Scholar
  79. Okuno, H., and Y. Miyashita. 1996. Expression of the transcription factor zif268 in the temporal cortex of monkeys during visual paired associate learning. European Journal of Neuroscience 8: 2118–2128.CrossRefGoogle Scholar
  80. Oyama, S. 2000. The ontogeny of information. Durham: Duke University Press.Google Scholar
  81. Pan, Q., O. Shai, L.J. Lee, B.J. Frey, and B.J. Blencowe. 2008. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nature Genetics 40: 1413–1415.CrossRefGoogle Scholar
  82. Pinker, S. 2002. The blank slate: The modern denial of human nature. New York: Viking.Google Scholar
  83. Platt, S.A., and C.A. Sanislow. 1988. Norm-of-reaction: Definition and misinterpretation of animal research. Journal of Comparative Psychology 102: 254–261.CrossRefGoogle Scholar
  84. Plomin, R. 1990. Nature and nurture: An introduction to human behavioral genetics. Belmont: Brooks/Cole.Google Scholar
  85. Plomin, R. 1994. Genetics and experience: The interplay between nature and nurture. Thousand Oaks: Sage.Google Scholar
  86. Plomin, R., J.C. DeFries, G.E. McClearn, and P. McGuffin. 2008. Behavioral genetics, 5th ed. New York: Worth.Google Scholar
  87. Proctor, R. 1988. Racial hygiene: Medicine under the Nazis. Cambridge, MA: Harvard University Press.Google Scholar
  88. Robert, J.S. 2004. Embryology, epigenesis, and evolution: Taking development seriously. New York: Cambridge University Press.CrossRefGoogle Scholar
  89. Rosen, K.M., M.A. McCormack, L. Villa Komaroff, and G.D. Mower. 1992. Brief visual experience induces immediate early gene expression in the cat visual cortex. Proceedings of the National Academy of Sciences of the United States of America 89: 5437–5441.CrossRefGoogle Scholar
  90. Rusak, B., H.A. Robertson, W. Wisden, and S.P. Hunt. 1990. Light pulses that shift rhythms induce gene expression in the suprachiasmatic nucleus. Science 248: 1237–1240.CrossRefGoogle Scholar
  91. Sesardic, N. 2005. Making sense of heritability. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
  92. Shaw, K.R.M., K. Van Horne, H. Zhang, and J. Boughman. 2008. Essay contest reveals misconceptions of high school students in genetics contest. Genetics 178: 1157–1168.CrossRefGoogle Scholar
  93. Shuel, R.W., and S.E. Dixon. 1960. The early establishment of dimorphism in the female honeybee, Apis mellifera, L. Insectes Sociaux 7: 265–282.CrossRefGoogle Scholar
  94. Small, M.F. 2011. Kids: How biology and culture shape the way we raise young children [Kindle Edition]. New York: Anchor Books.Google Scholar
  95. Stotz, K. 2006. With ‘genes’ like that, who needs an environment? Postgenomics’s argument for the ‘ontogeny of information’. Philosophy of Science 73: 905–917.CrossRefGoogle Scholar
  96. Thornhill, R., and C.T. Palmer. 2000. A natural history of rape: Biological bases of sexual coercion. Cambridge, MA: The MIT Press.Google Scholar
  97. Trafton, A. 2008. Human genes sing different tunes in different tissues. MIT TechTalk 53(8): 6.Google Scholar
  98. Wallman, J. 1979. A minimal visual restriction experiment: Preventing chicks from seeing their feet affects later responses to mealworms. Developmental Psychobiology 12: 391–397.CrossRefGoogle Scholar
  99. Walton, K.D., S. Harding, D. Anschel, Y.T. Harris, and R. Llinás. 2005. The effects of microgravity on the development of surface righting in rats. The Journal of Physiology 565: 593–608.CrossRefGoogle Scholar
  100. Wang, E.T., R. Sandberg, S. Luo, I. Khrebtukova, L. Zhang, C. Mayr, and C.B. Burge. 2008. Alternative isoform regulation in human tissue transcriptomes. Nature 456: 470–476.Google Scholar
  101. Weaver, I.C.G. 2007. Epigenetic programming by maternal behavior and pharmacological intervention: Nature versus nurture: Let’s call the whole thing off. Epigenetics 2: 22–28.CrossRefGoogle Scholar
  102. Weaver, I.C.G., N. Cervoni, F.A. Champagne, A.C. D’Alessio, S. Sharma, J.R. Seckl, and M.J. Meaney. 2004. Epigenetic programming by maternal behavior. Nature Neuroscience 7: 847–854.Google Scholar
  103. Weismann, A. 1894. The effect of external influences upon development. London: Frowde.Google Scholar
  104. West-Eberhard, M.J. 2003. Developmental plasticity and evolution. New York: Oxford University Press.Google Scholar
  105. Wheeler, M. 2010. Obesity gene, carried by more than a third of the U.S. population, leads to brain tissue loss. UCLA Newsroom. Retrieved from­gene-carried-by-half-the-157028.aspx. Accessed 24 Mar 2013.
  106. Yamagata, S., A. Suzuki, J. Ando, Y. Ono, N. Kijima, K. Yoshimura, et al. 2006. Is the genetic structure of human personality universal? A cross-cultural twin study from North America, Europe, and Asia. Journal of Personality and Social Psychology 90: 987–998.CrossRefGoogle Scholar

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© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  1. 1.Pitzer CollegeClaremontUSA
  2. 2.Claremont Graduate UniversityClaremontUSA

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