Abstract
Daltroban reduced the progression of atherosclerotic lesions in diet-induced as well as genetically hypercholesterolemic rabbits, indicating the independency of the anti-atherosclerotic action of Daltroban from the nature of hypercholesterolemia.
Zusammenfassung
Daltroban verminderte die Atherosklerose bei Kaninchen mit sowohl einer futterinduzierten als auch einer genetischen Hypercholesterinämie. Dies zeigt, daß die antiatherosklerotische Wirkung von Daltroban unabhängig von der Art der Hypercholesterinämie ist. Unter beiden Versuchsbedingungen ist die Plättchenaggregation unter Daltroban deutlich gehemmt. Dies und die Reduktion der Cholesterylesterakkumulation auf zellulärer Ebene [11] könnten zum antiatherosklerotischen Effekt von Daltroban beitragen.
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© 1993 Springer Fachmedien Wiesbaden
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Pill, J., Wolff, S., Dörge, L., Stegmeier, K., Hartig, F., Metz, J. (1993). Pharmacological inhibition of atherosclerosis in diet-induced and genetically hypercholesterolemic rabbits. In: Heinle, H., Schulte, H., Schaefer, H.E. (eds) Diätetik und Arteriosklerose. Vieweg+Teubner Verlag, Wiesbaden. https://doi.org/10.1007/978-3-663-01942-8_65
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DOI: https://doi.org/10.1007/978-3-663-01942-8_65
Publisher Name: Vieweg+Teubner Verlag, Wiesbaden
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